These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

159 related items for PubMed ID: 16750362

  • 1. Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).
    Owen CP, Dhanani S, Patel CH, Shahid I, Ahmed S.
    Bioorg Med Chem Lett; 2006 Aug 01; 16(15):4011-5. PubMed ID: 16750362
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of phenyl alkyl imidazole-based compounds as potent inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).
    Owen CP, Shahid I, Olusanjo MS, Patel CH, Dhanani S, Ahmed S.
    J Steroid Biochem Mol Biol; 2008 Jul 01; 111(1-2):117-27. PubMed ID: 18620055
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, biochemical evaluation of a range of potent 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-Hydroxylase/17,20-Lyase (P45017alpha).
    Shahid I, Patel CH, Dhanani S, Owen CP, Ahmed S.
    J Steroid Biochem Mol Biol; 2008 May 01; 110(1-2):18-29. PubMed ID: 18407491
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biochemical evaluation of a range of sulfonated derivatives of 4-hydroxybenzyl imidazole as highly potent inhibitors of rat testicular 17alpha-hydroxylase/17,20-lyase (P-450(17alpha)).
    Ahmed S, Shahid I, Dhanani S, Owen CP.
    Bioorg Med Chem Lett; 2009 Aug 15; 19(16):4698-701. PubMed ID: 19608417
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).
    Patel CH, Dhanani S, Owen CP, Ahmed S.
    Bioorg Med Chem Lett; 2006 Sep 15; 16(18):4752-6. PubMed ID: 16870430
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17alpha-hydroxylase/17,20-lyase (P45017alpha) derived from rat testicular microsomes.
    Owen CP, Shahid I, Lee WY, Ahmed S.
    Bioorg Med Chem Lett; 2010 Sep 01; 20(17):5345-8. PubMed ID: 20675132
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological evaluation of imidazole based compounds as cytochrome P-450 inhibitors.
    Ahmed S, Smith JH, Nicholls PJ, Whomsley R, Cariuk P.
    Drug Des Discov; 1995 Aug 01; 13(1):27-41. PubMed ID: 8882899
    [Abstract] [Full Text] [Related]

  • 8. A novel molecular modelling study of inhibitors of the 17alpha-hydroxylase component of the enzyme system 17alpha-hydroxylase/17,20-lyase (P-450(17alpha)).
    Ahmed S.
    Bioorg Med Chem; 1999 Aug 01; 7(8):1487-96. PubMed ID: 10482440
    [Abstract] [Full Text] [Related]

  • 9. Imidazole substituted biphenyls: a new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer.
    Wachall BG, Hector M, Zhuang Y, Hartmann RW.
    Bioorg Med Chem; 1999 Sep 01; 7(9):1913-24. PubMed ID: 10530940
    [Abstract] [Full Text] [Related]

  • 10. Novel imidazolyl and triazolyl substituted biphenyl compounds: synthesis and evaluation as nonsteroidal inhibitors of human 17alpha-hydroxylase-C17, 20-lyase (P450 17).
    Zhuang Y, Wachall BG, Hartmann RW.
    Bioorg Med Chem; 2000 Jun 01; 8(6):1245-52. PubMed ID: 10896104
    [Abstract] [Full Text] [Related]

  • 11. Some 1-[(benzofuran-2-yl)methyl]imidazoles as inhibitors of 17 alpha-hydroxylase: 17, 20-lyase (P450 17) and their specificity patterns.
    Bahshwan SA, Owen CP, Nicholls PJ, Smith HJ, Ahmadi M.
    J Pharm Pharmacol; 1998 Oct 01; 50(10):1109-16. PubMed ID: 9821656
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge.
    Hu Q, Negri M, Jahn-Hoffmann K, Zhuang Y, Olgen S, Bartels M, Müller-Vieira U, Lauterbach T, Hartmann RW.
    Bioorg Med Chem; 2008 Aug 15; 16(16):7715-27. PubMed ID: 18674917
    [Abstract] [Full Text] [Related]

  • 13. Modeling study of some inhibitors of 17,20-lyase, a component of the enzyme 17 alpha-hydroxylase/17,20-lyase: a novel approach.
    Ahmed S, Keane J.
    Biochem Biophys Res Commun; 1998 Dec 18; 253(2):273-6. PubMed ID: 9878527
    [Abstract] [Full Text] [Related]

  • 14. Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer.
    Njar VC, Kato K, Nnane IP, Grigoryev DN, Long BJ, Brodie AM.
    J Med Chem; 1998 Mar 12; 41(6):902-12. PubMed ID: 9526564
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure.
    Jagusch C, Negri M, Hille UE, Hu Q, Bartels M, Jahn-Hoffmann K, Pinto-Bazurco Mendieta MA, Rodenwaldt B, Müller-Vieira U, Schmidt D, Lauterbach T, Recanatini M, Cavalli A, Hartmann RW.
    Bioorg Med Chem; 2008 Feb 15; 16(4):1992-2010. PubMed ID: 18061460
    [Abstract] [Full Text] [Related]

  • 16. 17-Imidazolyl, pyrazolyl, and isoxazolyl androstene derivatives. Novel steroidal inhibitors of human cytochrome C17,20-lyase (P450(17 alpha).
    Ling YZ, Li JS, Liu Y, Kato K, Klus GT, Brodie A.
    J Med Chem; 1997 Sep 26; 40(20):3297-304. PubMed ID: 9379450
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, 17α-hydroxylase-C17,20-lyase Inhibitory and 5AR Reductase Activity of Novel Pregnenolone Derivatives.
    Banday AH, Shameem SA, Banday JA, Ganaie BA.
    Anticancer Agents Med Chem; 2018 Sep 26; 18(13):1919-1926. PubMed ID: 29697032
    [Abstract] [Full Text] [Related]

  • 18. 17,20-Lyase inhibitors. Part 3: Design, synthesis, and structure-activity relationships of biphenylylmethylimidazole derivatives as novel 17,20-lyase inhibitors.
    Kaku T, Tsujimoto S, Matsunaga N, Tanaka T, Hara T, Yamaoka M, Kusaka M, Tasaka A.
    Bioorg Med Chem; 2011 Apr 01; 19(7):2428-42. PubMed ID: 21429754
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and evaluation of 17-aliphatic heterocycle-substituted steroidal inhibitors of 17alpha-hydroxylase/C17-20-lyase (P450 17).
    Hartmann RW, Hector M, Wachall BG, Palusczak A, Palzer M, Huch V, Veith M.
    J Med Chem; 2000 Nov 16; 43(23):4437-45. PubMed ID: 11087568
    [Abstract] [Full Text] [Related]

  • 20. YM116, 2-(1H-imidazol-4-ylmethyl)-9H-carbazole, decreases adrenal androgen synthesis by inhibiting C17-20 lyase activity in NCI-H295 human adrenocortical carcinoma cells.
    Ideyama Y, Kudoh M, Tanimoto K, Susaki Y, Nanya T, Nakahara T, Ishikawa H, Fujikura T, Akaza H, Shikama H.
    Jpn J Pharmacol; 1999 Feb 16; 79(2):213-20. PubMed ID: 10202857
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 8.