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Journal Abstract Search

511 related items for PubMed ID: 16763014

  • 1. Prominent but reverse stereoselectivity in propranolol glucuronidation by human UDP-glucuronosyltransferases 1A9 and 1A10.
    Sten T, Qvisen S, Uutela P, Luukkanen L, Kostiainen R, Finel M.
    Drug Metab Dispos; 2006 Sep; 34(9):1488-94. PubMed ID: 16763014
    [Abstract] [Full Text] [Related]

  • 2. Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7.
    Hanioka N, Hayashi K, Shimizudani T, Nagaoka K, Koeda A, Naito S, Narimatsu S.
    Pharmacology; 2008 Sep; 82(4):293-303. PubMed ID: 18936551
    [Abstract] [Full Text] [Related]

  • 3. How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?
    Itäaho K, Laakkonen L, Finel M.
    Drug Metab Dispos; 2010 Apr; 38(4):687-96. PubMed ID: 20089735
    [Abstract] [Full Text] [Related]

  • 4. The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.
    Itäaho K, Mackenzie PI, Ikushiro S, Miners JO, Finel M.
    Drug Metab Dispos; 2008 Nov; 36(11):2307-15. PubMed ID: 18719240
    [Abstract] [Full Text] [Related]

  • 5. The glucuronidation of Delta4-3-Keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective substrates for UGT2B7.
    Bowalgaha K, Elliot DJ, Mackenzie PI, Knights KM, Miners JO.
    Drug Metab Dispos; 2007 Mar; 35(3):363-70. PubMed ID: 17151189
    [Abstract] [Full Text] [Related]

  • 6. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H, Kume T.
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [Abstract] [Full Text] [Related]

  • 7. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
    Shiraga T, Yajima K, Suzuki K, Suzuki K, Hashimoto T, Iwatsubo T, Miyashita A, Usui T.
    Drug Metab Dispos; 2012 Feb; 40(2):276-82. PubMed ID: 22031623
    [Abstract] [Full Text] [Related]

  • 8. Stereoselective metabolism of propranolol glucuronidation by human UDP-glucuronosyltransferases 2B7 and 1A9.
    Yu L, Qian M, Liu Y, Yao T, Zeng S.
    Chirality; 2010 May 05; 22(4):456-61. PubMed ID: 19644937
    [Abstract] [Full Text] [Related]

  • 9. Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases.
    Kuuranne T, Kurkela M, Thevis M, Schänzer W, Finel M, Kostiainen R.
    Drug Metab Dispos; 2003 Sep 05; 31(9):1117-24. PubMed ID: 12920167
    [Abstract] [Full Text] [Related]

  • 10. Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.
    Li T, Zheng Y, Fu F, Ji H, Chen X, Zhao Y, Zhao D, Li N, Zhang L.
    Xenobiotica; 2011 Jul 05; 41(7):530-7. PubMed ID: 21524190
    [Abstract] [Full Text] [Related]

  • 11. Characterization of hepatic and intestinal glucuronidation of magnolol: application of the relative activity factor approach to decipher the contributions of multiple UDP-glucuronosyltransferase isoforms.
    Zhu L, Ge G, Zhang H, Liu H, He G, Liang S, Zhang Y, Fang Z, Dong P, Finel M, Yang L.
    Drug Metab Dispos; 2012 Mar 05; 40(3):529-38. PubMed ID: 22180045
    [Abstract] [Full Text] [Related]

  • 12. Stereoselectivity and interaction between the glucuronidation of S-(-)- and R-(+)-propranolol in rat hepatic microsomes pretreated with different inducers.
    Luan LJ, Shao Q, Zeng S.
    Pharmazie; 2005 Mar 05; 60(3):221-4. PubMed ID: 15801678
    [Abstract] [Full Text] [Related]

  • 13. Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.
    Hanioka N, Naito T, Narimatsu S.
    Chemosphere; 2008 Dec 05; 74(1):33-6. PubMed ID: 18990428
    [Abstract] [Full Text] [Related]

  • 14. Glucuronidation of mono(2-ethylhexyl) phthalate in humans: roles of hepatic and intestinal UDP-glucuronosyltransferases.
    Hanioka N, Kinashi Y, Tanaka-Kagawa T, Isobe T, Jinno H.
    Arch Toxicol; 2017 Feb 05; 91(2):689-698. PubMed ID: 27071666
    [Abstract] [Full Text] [Related]

  • 15. The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan.
    Alonen A, Finel M, Kostiainen R.
    Biochem Pharmacol; 2008 Sep 15; 76(6):763-72. PubMed ID: 18674515
    [Abstract] [Full Text] [Related]

  • 16. Sulfinpyrazone C-glucuronidation is catalyzed selectively by human UDP-glucuronosyltransferase 1A9.
    Kerdpin O, Elliot DJ, Mackenzie PI, Miners JO.
    Drug Metab Dispos; 2006 Dec 15; 34(12):1950-3. PubMed ID: 16985098
    [Abstract] [Full Text] [Related]

  • 17. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
    Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T.
    Drug Metab Dispos; 2005 Jan 15; 33(1):23-30. PubMed ID: 15470160
    [Abstract] [Full Text] [Related]

  • 18. Stereoselective glucuronidation of carvedilol in human liver and intestinal microsomes.
    Hanioka N, Tanaka S, Moriguchi Y, Narimatsu S.
    Pharmacology; 2012 Jan 15; 90(3-4):117-24. PubMed ID: 22814440
    [Abstract] [Full Text] [Related]

  • 19. Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: a study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10.
    Mizuma T.
    Int J Pharm; 2009 Aug 13; 378(1-2):140-1. PubMed ID: 19486934
    [Abstract] [Full Text] [Related]

  • 20. Glucuronidation of racemic O-desmethyltramadol, the active metabolite of tramadol.
    Lehtonen P, Sten T, Aitio O, Kurkela M, Vuorensola K, Finel M, Kostiainen R.
    Eur J Pharm Sci; 2010 Nov 20; 41(3-4):523-30. PubMed ID: 20797434
    [Abstract] [Full Text] [Related]

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