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555 related items for PubMed ID: 16765624
1. Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate. Simpson NE, Han Z, Berendzen KM, Sweeney CA, Oca-Cossio JA, Constantinidis I, Stacpoole PW. Mol Genet Metab; 2006; 89(1-2):97-105. PubMed ID: 16765624 [Abstract] [Full Text] [Related]
2. Therapeutic potential of dichloroacetate for pyruvate dehydrogenase complex deficiency. Berendzen K, Theriaque DW, Shuster J, Stacpoole PW. Mitochondrion; 2006 Jun; 6(3):126-35. PubMed ID: 16725381 [Abstract] [Full Text] [Related]
3. Differential effect of DCA treatment on the pyruvate dehydrogenase complex in patients with severe PDHC deficiency. Fouque F, Brivet M, Boutron A, Vequaud C, Marsac C, Zabot MT, Benelli C. Pediatr Res; 2003 May; 53(5):793-9. PubMed ID: 12621116 [Abstract] [Full Text] [Related]
4. Detection of pyruvate metabolism disorders by culture of skin fibroblasts with dichloroacetate. Naito E, Kuroda Y, Takeda E, Yokota I, Kobashi H, Miyao M. Pediatr Res; 1988 Jun; 23(6):561-4. PubMed ID: 2839811 [Abstract] [Full Text] [Related]
5. In vitro effects of dichloroacetate and CO2 on hypoxic HeLa cells. Anderson KM, Jajeh J, Guinan P, Rubenstein M. Anticancer Res; 2009 Nov; 29(11):4579-88. PubMed ID: 20032407 [Abstract] [Full Text] [Related]
6. Isotopic evaluation of the metabolism of pyruvate and related substrates in normal adult volunteers and severely burned children: effect of dichloroacetate and glucose infusion. Wolfe RR, Jahoor F, Herndon DN, Miyoshi H. Surgery; 1991 Jul; 110(1):54-67. PubMed ID: 1866694 [Abstract] [Full Text] [Related]
7. MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy. Alexander JJ, Zwingmann C, Quigg R. Neurochem Int; 2005 Jul; 47(1-2):143-51. PubMed ID: 15893408 [Abstract] [Full Text] [Related]
8. Deficiency of pyruvate dehydrogenase complex in tissues of an eight month old infant. Hansikova H, Zeman J, Klement P, Technikova-Dobrova Z, Houstkova H, Houstek J, Papa S. Biochem Mol Biol Int; 1993 Dec; 31(6):1157-66. PubMed ID: 8193600 [Abstract] [Full Text] [Related]
9. Energy metabolism in astrocytes and neurons treated with manganese: relation among cell-specific energy failure, glucose metabolism, and intercellular trafficking using multinuclear NMR-spectroscopic analysis. Zwingmann C, Leibfritz D, Hazell AS. J Cereb Blood Flow Metab; 2003 Jun; 23(6):756-71. PubMed ID: 12796724 [Abstract] [Full Text] [Related]
10. Therapeutic potential of the mammalian pyruvate dehydrogenase kinases in the prevention of hyperglycaemia. Sugden MC, Holness MJ. Curr Drug Targets Immune Endocr Metabol Disord; 2002 Jul; 2(2):151-65. PubMed ID: 12476789 [Abstract] [Full Text] [Related]
11. Effects of dichloroacetate and ubiquinone infusions on glycolysis activity and thermal sensitivity during sepsis. L'Her E, Sebert P. J Lab Clin Med; 2004 Jun; 143(6):352-7. PubMed ID: 15192651 [Abstract] [Full Text] [Related]
12. Combining metabolic flux analysis tools and 13C NMR to estimate intracellular fluxes of cultured astrocytes. Teixeira AP, Santos SS, Carinhas N, Oliveira R, Alves PM. Neurochem Int; 2008 Feb; 52(3):478-86. PubMed ID: 17904693 [Abstract] [Full Text] [Related]
13. Brain energy metabolism in a sub-acute rat model of manganese neurotoxicity: an ex vivo nuclear magnetic resonance study using [1-13C]glucose. Zwingmann C, Leibfritz D, Hazell AS. Neurotoxicology; 2004 Jun; 25(4):573-87. PubMed ID: 15183011 [Abstract] [Full Text] [Related]
14. Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children. Stacpoole PW, Kerr DS, Barnes C, Bunch ST, Carney PR, Fennell EM, Felitsyn NM, Gilmore RL, Greer M, Henderson GN, Hutson AD, Neiberger RE, O'Brien RG, Perkins LA, Quisling RG, Shroads AL, Shuster JJ, Silverstein JH, Theriaque DW, Valenstein E. Pediatrics; 2006 May; 117(5):1519-31. PubMed ID: 16651305 [Abstract] [Full Text] [Related]
15. Metabolic profiling by 13C-NMR spectroscopy: [1,2-13C2]glucose reveals a heterogeneous metabolism in human leukemia T cells. Miccheli A, Tomassini A, Puccetti C, Valerio M, Peluso G, Tuccillo F, Calvani M, Manetti C, Conti F. Biochimie; 2006 May; 88(5):437-48. PubMed ID: 16359766 [Abstract] [Full Text] [Related]
16. Effects of homocysteine on metabolic pathways in cultured astrocytes. Jin Y, Brennan L. Neurochem Int; 2008 Jun; 52(8):1410-5. PubMed ID: 18417255 [Abstract] [Full Text] [Related]
17. Systemic deficiency of the first component of the pyruvate dehydrogenase complex. Kerr DS, Ho L, Berlin CM, Lanoue KF, Towfighi J, Hoppel CL, Lusk MM, Gondek CM, Patel MS. Pediatr Res; 1987 Sep; 22(3):312-8. PubMed ID: 3116495 [Abstract] [Full Text] [Related]
18. A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency. Odièvre MH, Chretien D, Munnich A, Robinson BH, Dumoulin R, Masmoudi S, Kadhom N, Rötig A, Rustin P, Bonnefont JP. Hum Mutat; 2005 Mar; 25(3):323-4. PubMed ID: 15712224 [Abstract] [Full Text] [Related]
19. Pyruvate dehydrogenase activity and malonyl CoA levels in normal and ischemic swine myocardium: effects of dichloroacetate. Stanley WC, Hernandez LA, Spires D, Bringas J, Wallace S, McCormack JG. J Mol Cell Cardiol; 1996 May; 28(5):905-14. PubMed ID: 8762030 [Abstract] [Full Text] [Related]