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Journal Abstract Search

168 related items for PubMed ID: 1676635

  • 61. Role of hepatic microsomal and purified cytochrome P-450 in one-electron reduction of two quinone imines and concomitant reduction of molecular oxygen.
    van de Straat R, de Vries J, Vermeulen NP.
    Biochem Pharmacol; 1987 Mar 01; 36(5):613-9. PubMed ID: 3030331
    [Abstract] [Full Text] [Related]

  • 62. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice.
    Zaher H, Buters JT, Ward JM, Bruno MK, Lucas AM, Stern ST, Cohen SD, Gonzalez FJ.
    Toxicol Appl Pharmacol; 1998 Sep 01; 152(1):193-9. PubMed ID: 9772215
    [Abstract] [Full Text] [Related]

  • 63. Enolate-Forming Phloretin Pharmacophores: Hepatoprotection in an Experimental Model of Drug-Induced Toxicity.
    Geohagen BC, Vydyanathan A, Kosharskyy B, Shaparin N, Gavin T, LoPachin RM.
    J Pharmacol Exp Ther; 2016 Jun 01; 357(3):476-86. PubMed ID: 27029584
    [Abstract] [Full Text] [Related]

  • 64. Effect of fasting on metabolite-mediated hepatotoxicity in the rat.
    Pessayre D, Dolder A, Artigou JY, Wandscheer JC, Descatoire V, Degott C, Benhamou JP.
    Gastroenterology; 1979 Aug 01; 77(2):264-71. PubMed ID: 109346
    [Abstract] [Full Text] [Related]

  • 65. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C, Gelboin HV, Park SS, Pearce R, Parkinson A, Kupfer D.
    Drug Metab Dispos; 1993 Aug 01; 21(4):645-56. PubMed ID: 8104124
    [Abstract] [Full Text] [Related]

  • 66. Cataract formation by a semiquinone metabolite of acetaminophen in mice: possible involvement of Ca(2+)and calpain activation.
    Qian W, Shichi H.
    Exp Eye Res; 2000 Dec 01; 71(6):567-74. PubMed ID: 11095908
    [Abstract] [Full Text] [Related]

  • 67. Cytochrome P-450-mediated oxidation of substrates by electron-transfer; role of oxygen radicals and of 1- and 2-electron oxidation of paracetamol.
    van de Straat R, Vromans RM, Bosman P, de Vries J, Vermeulen NP.
    Chem Biol Interact; 1988 Dec 01; 64(3):267-80. PubMed ID: 3342453
    [Abstract] [Full Text] [Related]

  • 68. Direct protection against acetaminophen hepatotoxicity by propylthiouracil. In vivo and in vitro studies in rats and mice.
    Yamada T, Ludwig S, Kuhlenkamp J, Kaplowitz N.
    J Clin Invest; 1981 Mar 01; 67(3):688-95. PubMed ID: 7204554
    [Abstract] [Full Text] [Related]

  • 69. Transiently altered acetaminophen metabolism after liver transplantation.
    Park JM, Lin YS, Calamia JC, Thummel KE, Slattery JT, Kalhorn TF, Carithers RL, Levy AE, Marsh CL, Hebert MF.
    Clin Pharmacol Ther; 2003 Jun 01; 73(6):545-53. PubMed ID: 12811364
    [Abstract] [Full Text] [Related]

  • 70. Sex-related differences in mouse renal metabolism and toxicity of acetaminophen.
    Hu JJ, Lee MJ, Vapiwala M, Reuhl K, Thomas PE, Yang CS.
    Toxicol Appl Pharmacol; 1993 Sep 01; 122(1):16-26. PubMed ID: 8378930
    [Abstract] [Full Text] [Related]

  • 71. Acetaminophen binds to mouse hepatic and renal DNA at human therapeutic doses.
    Rogers LK, Moorthy B, Smith CV.
    Chem Res Toxicol; 1997 Apr 01; 10(4):470-6. PubMed ID: 9114986
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  • 74. Mitochondrial versus microsomal bioactivation of paracetamol by human liver and kidney tissues.
    Arzuk E, Tokdemir M, Orhan H.
    Toxicol Lett; 2022 Jun 15; 363():36-44. PubMed ID: 35595037
    [Abstract] [Full Text] [Related]

  • 75. Use of a systems model of drug-induced liver injury (DILIsym(®)) to elucidate the mechanistic differences between acetaminophen and its less-toxic isomer, AMAP, in mice.
    Howell BA, Siler SQ, Watkins PB.
    Toxicol Lett; 2014 Apr 21; 226(2):163-72. PubMed ID: 24560604
    [Abstract] [Full Text] [Related]

  • 76. Comparative Toxicity and Metabolism of N-Acyl Homologues of Acetaminophen and Its Isomer 3'-Hydroxyacetanilide.
    Koen YM, Liu K, Shinogle H, Williams TD, Hanzlik RP.
    Chem Res Toxicol; 2016 Nov 21; 29(11):1857-1864. PubMed ID: 27680534
    [Abstract] [Full Text] [Related]

  • 77. Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
    Potter WZ, Davis DC, Mitchell JR, Jollow DJ, Gillette JR, Brodie BB.
    J Pharmacol Exp Ther; 1973 Oct 21; 187(1):203-10. PubMed ID: 4147720
    [No Abstract] [Full Text] [Related]

  • 78. Rat liver ADP-ribose pyrophosphatase-I as an in vitro target of the acetaminophen metabolite N-acetyl-p-benzoquinoneimine.
    Ribeiro JM, Agudo A, Costas MJ, Cameselle JC.
    Biochim Biophys Acta; 1997 Oct 20; 1336(3):403-8. PubMed ID: 9367167
    [Abstract] [Full Text] [Related]

  • 79. Metabolic Competency of Larval Zebrafish in Drug-Induced Liver Injury: A Case Study of Acetaminophen Poisoning.
    Chen Y, Song W, Ge W, Yan R.
    Toxicol Sci; 2022 Sep 24; 189(2):175-185. PubMed ID: 35944217
    [Abstract] [Full Text] [Related]

  • 80. N-acetyl-p-benzoquinone imine-induced changes in the energy metabolism in hepatocytes.
    Andersson BS, Rundgren M, Nelson SD, Harder S.
    Chem Biol Interact; 1990 Sep 24; 75(2):201-11. PubMed ID: 2369786
    [Abstract] [Full Text] [Related]

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