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172 related items for PubMed ID: 16769157

  • 1. Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.
    Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM.
    Neurobiol Aging; 2007 Jun; 28(6):824-30. PubMed ID: 16769157
    [Abstract] [Full Text] [Related]

  • 2. Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders.
    Caccamo A, Oddo S, Sugarman MC, Akbari Y, LaFerla FM.
    Neurobiol Aging; 2005 May; 26(5):645-54. PubMed ID: 15708439
    [Abstract] [Full Text] [Related]

  • 3. Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.
    Farris W, Leissring MA, Hemming ML, Chang AY, Selkoe DJ.
    Biochemistry; 2005 May 03; 44(17):6513-25. PubMed ID: 15850385
    [Abstract] [Full Text] [Related]

  • 4. [Cerebral proteolysis of amiloid-b peptide: relevance of insulin-degrading enzyme in Alzheimer's disease].
    Leal MC, Fernandez Gamba A, Morelli L, Castaño EM.
    Medicina (B Aires); 2009 May 03; 69(4):466-72. PubMed ID: 19770104
    [Abstract] [Full Text] [Related]

  • 5. Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.
    Blomqvist ME, Chalmers K, Andreasen N, Bogdanovic N, Wilcock GK, Cairns NJ, Feuk L, Brookes AJ, Love S, Blennow K, Kehoe PG, Prince JA.
    Neurobiol Aging; 2005 Jun 03; 26(6):795-802. PubMed ID: 15718037
    [Abstract] [Full Text] [Related]

  • 6. Elucidation of interactions of Alzheimer amyloid beta peptides (Abeta40 and Abeta42) with insulin degrading enzyme: a molecular dynamics study.
    Bora RP, Prabhakar R.
    Biochemistry; 2010 May 11; 49(18):3947-56. PubMed ID: 20380468
    [Abstract] [Full Text] [Related]

  • 7. Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment.
    Mufson EJ, Chen EY, Cochran EJ, Beckett LA, Bennett DA, Kordower JH.
    Exp Neurol; 1999 Aug 11; 158(2):469-90. PubMed ID: 10415154
    [Abstract] [Full Text] [Related]

  • 8. Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.
    Vepsäläinen S, Hiltunen M, Helisalmi S, Wang J, van Groen T, Tanila H, Soininen H.
    Neurosci Lett; 2008 Jun 20; 438(2):216-20. PubMed ID: 18455870
    [Abstract] [Full Text] [Related]

  • 9. Discriminating accuracy of medial temporal lobe volumetry and fMRI in mild cognitive impairment.
    Jauhiainen AM, Pihlajamäki M, Tervo S, Niskanen E, Tanila H, Hänninen T, Vanninen RL, Soininen H.
    Hippocampus; 2009 Feb 20; 19(2):166-75. PubMed ID: 18777563
    [Abstract] [Full Text] [Related]

  • 10. Nitric oxide inhibits insulin-degrading enzyme activity and function through S-nitrosylation.
    Cordes CM, Bennett RG, Siford GL, Hamel FG.
    Biochem Pharmacol; 2009 Mar 15; 77(6):1064-73. PubMed ID: 19154729
    [Abstract] [Full Text] [Related]

  • 11. Insulin degrading enzyme is localized predominantly at the cell surface of polarized and unpolarized human cerebrovascular endothelial cell cultures.
    Lynch JA, George AM, Eisenhauer PB, Conn K, Gao W, Carreras I, Wells JM, McKee A, Ullman MD, Fine RE.
    J Neurosci Res; 2006 May 15; 83(7):1262-70. PubMed ID: 16511862
    [Abstract] [Full Text] [Related]

  • 12. Down-regulation of insulin-degrading enzyme by presenilin 1 V97L mutant potentially underlies increased levels of amyloid beta 42.
    Qin W, Jia J.
    Eur J Neurosci; 2008 May 15; 27(9):2425-32. PubMed ID: 18445230
    [Abstract] [Full Text] [Related]

  • 13. Copper(I) and copper(II) inhibit Aβ peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease.
    Grasso G, Pietropaolo A, Spoto G, Pappalardo G, Tundo GR, Ciaccio C, Coletta M, Rizzarelli E.
    Chemistry; 2011 Feb 25; 17(9):2752-62. PubMed ID: 21274957
    [Abstract] [Full Text] [Related]

  • 14. ApoE 4 reduces the expression of Abeta degrading enzyme IDE by activating the NMDA receptor in hippocampal neurons.
    Du J, Chang J, Guo S, Zhang Q, Wang Z.
    Neurosci Lett; 2009 Oct 23; 464(2):140-5. PubMed ID: 19616072
    [Abstract] [Full Text] [Related]

  • 15. Insulin-degrading enzyme antagonizes insulin-dependent tissue growth and Abeta-induced neurotoxicity in Drosophila.
    Tsuda M, Kobayashi T, Matsuo T, Aigaki T.
    FEBS Lett; 2010 Jul 02; 584(13):2916-20. PubMed ID: 20493190
    [Abstract] [Full Text] [Related]

  • 16. Beta-amyloid pathology in the entorhinal cortex of rats induces memory deficits: implications for Alzheimer's disease.
    Sipos E, Kurunczi A, Kasza A, Horváth J, Felszeghy K, Laroche S, Toldi J, Párducz A, Penke B, Penke Z.
    Neuroscience; 2007 Jun 15; 147(1):28-36. PubMed ID: 17499931
    [Abstract] [Full Text] [Related]

  • 17. Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity.
    Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M.
    J Mol Biol; 2009 Feb 06; 385(5):1556-67. PubMed ID: 19073193
    [Abstract] [Full Text] [Related]

  • 18. Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid beta 42, medial temporal lobe atrophy and homocysteine.
    Blasko I, Jellinger K, Kemmler G, Krampla W, Jungwirth S, Wichart I, Tragl KH, Fischer P.
    Neurobiol Aging; 2008 Jan 06; 29(1):1-11. PubMed ID: 17055615
    [Abstract] [Full Text] [Related]

  • 19. Accumulation of BRI2-BRICHOS ectodomain correlates with a decreased clearance of Aβ by insulin degrading enzyme (IDE) in Alzheimer's disease.
    Del Campo M, Stargardt A, Veerhuis R, Reits E, Teunissen CE.
    Neurosci Lett; 2015 Mar 04; 589():47-51. PubMed ID: 25597881
    [Abstract] [Full Text] [Related]

  • 20. Hippocampal volume and cortical sources of EEG alpha rhythms in mild cognitive impairment and Alzheimer disease.
    Babiloni C, Frisoni GB, Pievani M, Vecchio F, Lizio R, Buttiglione M, Geroldi C, Fracassi C, Eusebi F, Ferri R, Rossini PM.
    Neuroimage; 2009 Jan 01; 44(1):123-35. PubMed ID: 18805495
    [Abstract] [Full Text] [Related]

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