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Journal Abstract Search

463 related items for PubMed ID: 16776542

  • 1. Convergent synthesis of the quinolone substructure of BILN 2061 via carbonylative Sonogashira coupling/cyclization.
    Haddad N, Tan J, Farina V.
    J Org Chem; 2006 Jun 23; 71(13):5031-4. PubMed ID: 16776542
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of BILN 2061, an HCV NS3 protease inhibitor with proven antiviral effect in humans.
    Faucher AM, Bailey MD, Beaulieu PL, Brochu C, Duceppe JS, Ferland JM, Ghiro E, Gorys V, Halmos T, Kawai SH, Poirier M, Simoneau B, Tsantrizos YS, Llinàs-Brunet M.
    Org Lett; 2004 Aug 19; 6(17):2901-4. PubMed ID: 15330643
    [Abstract] [Full Text] [Related]

  • 3. Efficient large-scale synthesis of BILN 2061, a potent HCV protease inhibitor, by a convergent approach based on ring-closing metathesis.
    Yee NK, Farina V, Houpis IN, Haddad N, Frutos RP, Gallou F, Wang XJ, Wei X, Simpson RD, Feng X, Fuchs V, Xu Y, Tan J, Zhang L, Xu J, Smith-Keenan LL, Vitous J, Ridges MD, Spinelli EM, Johnson M, Donsbach K, Nicola T, Brenner M, Winter E, Kreye P, Samstag W.
    J Org Chem; 2006 Sep 15; 71(19):7133-45. PubMed ID: 16958506
    [Abstract] [Full Text] [Related]

  • 4. Pd-catalyzed copper-free carbonylative Sonogashira reaction of aryl iodides with alkynes for the synthesis of alkynyl ketones and flavones by using water as a solvent.
    Liang B, Huang M, You Z, Xiong Z, Lu K, Fathi R, Chen J, Yang Z.
    J Org Chem; 2005 Jul 22; 70(15):6097-100. PubMed ID: 16018709
    [Abstract] [Full Text] [Related]

  • 5. Unexpected domino reaction via Pd-catalyzed Sonogashira coupling of benzimidoyl chlorides with 1,6-enynes and cyclization to synthesize quinoline derivatives.
    Gao GL, Niu YN, Yan ZY, Wang HL, Wang GW, Shaukat A, Liang YM.
    J Org Chem; 2010 Feb 19; 75(4):1305-8. PubMed ID: 20088585
    [Abstract] [Full Text] [Related]

  • 6. RCM macrocyclization made practical: an efficient synthesis of HCV protease inhibitor BILN 2061.
    Shu C, Zeng X, Hao MH, Wei X, Yee NK, Busacca CA, Han Z, Farina V, Senanayake CH.
    Org Lett; 2008 Mar 20; 10(6):1303-6. PubMed ID: 18293994
    [Abstract] [Full Text] [Related]

  • 7. Low pressure Pd-catalyzed carbonylation in an ionic liquid using a multiphase microflow system.
    Rahman MT, Fukuyama T, Kamata N, Sato M, Ryu I.
    Chem Commun (Camb); 2006 Jun 04; (21):2236-8. PubMed ID: 16718314
    [Abstract] [Full Text] [Related]

  • 8. Palladium-catalyzed Sonogashira-coupling conjoined C-H activation: a regioselective tandem strategy to access indolo- and pyrrolo[1,2-a]quinolines.
    Shukla SP, Tiwari RK, Verma AK.
    J Org Chem; 2012 Nov 16; 77(22):10382-92. PubMed ID: 23083404
    [Abstract] [Full Text] [Related]

  • 9. Highly enantioselective quinoline synthesis via ene-type cyclization of 1,7-enynes catalyzed by a cationic BINAP-palladium(II) complex.
    Hatano M, Mikami K.
    J Am Chem Soc; 2003 Apr 23; 125(16):4704-5. PubMed ID: 12696877
    [Abstract] [Full Text] [Related]

  • 10. Let the best ring win: selective macrocycle formation through Pd-catalyzed or Cu-mediated alkyne homocoupling.
    Marsden JA, Miller JJ, Haley MM.
    Angew Chem Int Ed Engl; 2004 Mar 19; 43(13):1694-7. PubMed ID: 15038040
    [No Abstract] [Full Text] [Related]

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  • 12. Fused ring construction around pyrrole, indole, and related compounds via palladium-catalyzed oxidative coupling with alkynes.
    Yamashita M, Horiguchi H, Hirano K, Satoh T, Miura M.
    J Org Chem; 2009 Oct 02; 74(19):7481-8. PubMed ID: 19719122
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  • 16. Electrophile-driven regioselective synthesis of functionalized quinolines.
    Ali S, Zhu HT, Xia XF, Ji KG, Yang YF, Song XR, Liang YM.
    Org Lett; 2011 May 20; 13(10):2598-601. PubMed ID: 21491872
    [Abstract] [Full Text] [Related]

  • 17. Bismacrocyclic inhibitors of hepatitis C NS3/4a protease.
    McCauley JA, Rudd MT, Nguyen KT, McIntyre CJ, Romano JJ, Bush KJ, Varga SL, Ross CW, Carroll SS, DiMuzio J, Stahlhut MW, Olsen DB, Lyle TA, Vacca JP, Liverton NJ.
    Angew Chem Int Ed Engl; 2008 May 20; 47(47):9104-7. PubMed ID: 18925594
    [No Abstract] [Full Text] [Related]

  • 18. Pd(II)-catalyzed one-step construction of cycloalkane-fused indoles and its application in formal synthesis of (±)-aspidospermidine.
    Xia G, Han X, Lu X.
    Org Lett; 2014 Apr 04; 16(7):2058-61. PubMed ID: 24650163
    [Abstract] [Full Text] [Related]

  • 19. Macrocycloadditions leading to conformationally restricted small molecules.
    Looper RE, Pizzirani D, Schreiber SL.
    Org Lett; 2006 May 11; 8(10):2063-6. PubMed ID: 16671782
    [Abstract] [Full Text] [Related]

  • 20. Synthesis of multiply substituted alkylidene silacyclohexadiene derivatives via palladium-catalyzed insertion of alkynes into alkylidene silacyclobutenes.
    Liu J, Sun X, Miyazaki M, Liu L, Wang C, Xi Z.
    J Org Chem; 2007 Apr 13; 72(8):3137-40. PubMed ID: 17371073
    [Abstract] [Full Text] [Related]

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