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Journal Abstract Search

313 related items for PubMed ID: 16782767

  • 1. Use of cryopreserved human hepatocytes in sandwich culture to measure hepatobiliary transport.
    Bi YA, Kazolias D, Duignan DB.
    Drug Metab Dispos; 2006 Sep; 34(9):1658-65. PubMed ID: 16782767
    [Abstract] [Full Text] [Related]

  • 2. Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.
    De Bruyn T, Ye ZW, Peeters A, Sahi J, Baes M, Augustijns PF, Annaert PP.
    Eur J Pharm Sci; 2011 Jul 17; 43(4):297-307. PubMed ID: 21605667
    [Abstract] [Full Text] [Related]

  • 3. Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes.
    Kotani N, Maeda K, Watanabe T, Hiramatsu M, Gong LK, Bi YA, Takezawa T, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2011 Sep 17; 39(9):1503-10. PubMed ID: 21673128
    [Abstract] [Full Text] [Related]

  • 4. Hepatobiliary disposition in primary cultures of dog and monkey hepatocytes.
    Rose KA, Kostrubsky V, Sahi J.
    Mol Pharm; 2006 Sep 17; 3(3):266-74. PubMed ID: 16749858
    [Abstract] [Full Text] [Related]

  • 5. Characterization of digoxin uptake in sandwich-cultured human hepatocytes.
    Kimoto E, Chupka J, Xiao Y, Bi YA, Duignan DB.
    Drug Metab Dispos; 2011 Jan 17; 39(1):47-53. PubMed ID: 20926619
    [Abstract] [Full Text] [Related]

  • 6. Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.
    Hartman JC, Brouwer K, Mandagere A, Melvin L, Gorczynski R.
    Can J Physiol Pharmacol; 2010 Jun 17; 88(6):682-91. PubMed ID: 20628435
    [Abstract] [Full Text] [Related]

  • 7. The impact of solute carrier (SLC) drug uptake transporter loss in human and rat cryopreserved hepatocytes on clearance predictions.
    Lundquist P, Lööf J, Sohlenius-Sternbeck AK, Floby E, Johansson J, Bylund J, Hoogstraate J, Afzelius L, Andersson TB.
    Drug Metab Dispos; 2014 Mar 17; 42(3):469-80. PubMed ID: 24396146
    [Abstract] [Full Text] [Related]

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  • 9. Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition.
    Deharde D, Schneider C, Hiller T, Fischer N, Kegel V, Lübberstedt M, Freyer N, Hengstler JG, Andersson TB, Seehofer D, Pratschke J, Zeilinger K, Damm G.
    Arch Toxicol; 2016 Oct 17; 90(10):2497-511. PubMed ID: 27325308
    [Abstract] [Full Text] [Related]

  • 10. Xenobiotics inhibit hepatic uptake and biliary excretion of taurocholate in rat hepatocytes.
    Kemp DC, Zamek-Gliszczynski MJ, Brouwer KL.
    Toxicol Sci; 2005 Feb 17; 83(2):207-14. PubMed ID: 15509663
    [Abstract] [Full Text] [Related]

  • 11. Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes.
    Jørgensen L, Van Beek J, Lund S, Schousboe A, Badolo L.
    Eur J Pharm Sci; 2007 Feb 17; 30(2):181-9. PubMed ID: 17174077
    [Abstract] [Full Text] [Related]

  • 12. Differential regulation of drug transporter expression by hepatocyte growth factor in primary human hepatocytes.
    Le Vee M, Lecureur V, Moreau A, Stieger B, Fardel O.
    Drug Metab Dispos; 2009 Nov 17; 37(11):2228-35. PubMed ID: 19661216
    [Abstract] [Full Text] [Related]

  • 13. Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta.
    Le Vee M, Gripon P, Stieger B, Fardel O.
    Drug Metab Dispos; 2008 Feb 17; 36(2):217-22. PubMed ID: 17991769
    [Abstract] [Full Text] [Related]

  • 14. Identification of interspecies difference in efflux transporters of hepatocytes from dog, rat, monkey and human.
    Li M, Yuan H, Li N, Song G, Zheng Y, Baratta M, Hua F, Thurston A, Wang J, Lai Y.
    Eur J Pharm Sci; 2008 Sep 02; 35(1-2):114-26. PubMed ID: 18639632
    [Abstract] [Full Text] [Related]

  • 15. Uptake and efflux transporters for conjugates in human hepatocytes.
    Keppler D.
    Methods Enzymol; 2005 Sep 02; 400():531-42. PubMed ID: 16399368
    [Abstract] [Full Text] [Related]

  • 16. Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes.
    Fukuda H, Ohashi R, Tsuda-Tsukimoto M, Tamai I.
    Drug Metab Dispos; 2008 Jul 02; 36(7):1275-82. PubMed ID: 18388177
    [Abstract] [Full Text] [Related]

  • 17. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.
    Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB.
    Gastroenterology; 2006 May 02; 130(6):1793-806. PubMed ID: 16697742
    [Abstract] [Full Text] [Related]

  • 18. Quantification of Drug-Induced Inhibition of Canalicular Cholyl-l-Lysyl-Fluorescein Excretion From Hepatocytes by High Content Cell Imaging.
    Barber JA, Stahl SH, Summers C, Barrett G, Park BK, Foster JR, Kenna JG.
    Toxicol Sci; 2015 Nov 02; 148(1):48-59. PubMed ID: 26220638
    [Abstract] [Full Text] [Related]

  • 19. Comparison of intrinsic metabolic clearance in fresh and cryopreserved human hepatocytes.
    Floby E, Johansson J, Hoogstraate J, Hewitt NJ, Hill J, Sohlenius-Sternbeck AK.
    Xenobiotica; 2009 Sep 02; 39(9):656-62. PubMed ID: 19622023
    [Abstract] [Full Text] [Related]

  • 20. Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury.
    Yang K, Pfeifer ND, Köck K, Brouwer KL.
    J Pharmacol Exp Ther; 2015 May 02; 353(2):415-23. PubMed ID: 25711339
    [Abstract] [Full Text] [Related]

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