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344 related items for PubMed ID: 16784226

  • 1. Influencing cellular transformation by modulating the rates of GTP hydrolysis by Cdc42.
    Fidyk N, Wang JB, Cerione RA.
    Biochemistry; 2006 Jun 27; 45(25):7750-62. PubMed ID: 16784226
    [Abstract] [Full Text] [Related]

  • 2. The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation.
    Wu WJ, Erickson JW, Lin R, Cerione RA.
    Nature; 2000 Jun 15; 405(6788):800-4. PubMed ID: 10866202
    [Abstract] [Full Text] [Related]

  • 3. Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth.
    Murphy GA, Solski PA, Jillian SA, Pérez de la Ossa P, D'Eustachio P, Der CJ, Rush MG.
    Oncogene; 1999 Jul 01; 18(26):3831-45. PubMed ID: 10445846
    [Abstract] [Full Text] [Related]

  • 4. Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42.
    Kintscher C, Groemping Y.
    J Mol Biol; 2009 Mar 27; 387(2):270-83. PubMed ID: 19356586
    [Abstract] [Full Text] [Related]

  • 5. Vav transformation requires activation of multiple GTPases and regulation of gene expression.
    Palmby TR, Abe K, Karnoub AE, Der CJ.
    Mol Cancer Res; 2004 Dec 27; 2(12):702-11. PubMed ID: 15634759
    [Abstract] [Full Text] [Related]

  • 6. The CDC42-specific inhibitor derived from ACK-1 blocks v-Ha-Ras-induced transformation.
    Nur-E-Kamal MS, Kamal JM, Qureshi MM, Maruta H.
    Oncogene; 1999 Dec 16; 18(54):7787-93. PubMed ID: 10618719
    [Abstract] [Full Text] [Related]

  • 7. A Cdc42 mutant specifically activated by intersectin.
    Smith WJ, Hamel B, Yohe ME, Sondek J, Cerione RA, Snyder JT.
    Biochemistry; 2005 Oct 11; 44(40):13282-90. PubMed ID: 16201754
    [Abstract] [Full Text] [Related]

  • 8. Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells.
    Shen Y, Li N, Wu S, Zhou Y, Shan Y, Zhang Q, Ding C, Yuan Q, Zhao F, Zeng R, Zhu X.
    Dev Cell; 2008 Mar 11; 14(3):342-53. PubMed ID: 18331715
    [Abstract] [Full Text] [Related]

  • 9. Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains.
    Wang L, Zhu K, Zheng Y.
    Biochemistry; 2004 Nov 23; 43(46):14584-93. PubMed ID: 15544329
    [Abstract] [Full Text] [Related]

  • 10. Antiapoptotic Cdc42 mutants are potent activators of cellular transformation.
    Tu SS, Wu WJ, Yang W, Nolbant P, Hahn K, Cerione RA.
    Biochemistry; 2002 Oct 15; 41(41):12350-8. PubMed ID: 12369824
    [Abstract] [Full Text] [Related]

  • 11. An activating mutant of Cdc42 that fails to interact with Rho GDP-dissociation inhibitor localizes to the plasma membrane and mediates actin reorganization.
    Gibson RM, Gandhi PN, Tong X, Miyoshi J, Takai Y, Konieczkowski M, Sedor JR, Wilson-Delfosse AL.
    Exp Cell Res; 2004 Dec 10; 301(2):211-22. PubMed ID: 15530857
    [Abstract] [Full Text] [Related]

  • 12. Distinct involvement of cdc42 and RhoA GTPases in actin organization and cell shape in untransformed and Dbl oncogene transformed NIH3T3 cells.
    Olivo C, Vanni C, Mancini P, Silengo L, Torrisi MR, Tarone G, Defilippi P, Eva A.
    Oncogene; 2000 Mar 09; 19(11):1428-36. PubMed ID: 10723134
    [Abstract] [Full Text] [Related]

  • 13. BNIP-2 induces cell elongation and membrane protrusions by interacting with Cdc42 via a unique Cdc42-binding motif within its BNIP-2 and Cdc42GAP homology domain.
    Zhou YT, Guy GR, Low BC.
    Exp Cell Res; 2005 Feb 15; 303(2):263-74. PubMed ID: 15652341
    [Abstract] [Full Text] [Related]

  • 14. Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L.
    Wang JB, Wu WJ, Cerione RA.
    J Biol Chem; 2005 Jun 17; 280(24):22883-91. PubMed ID: 15824104
    [Abstract] [Full Text] [Related]

  • 15. Requirement for Akt-mediated survival in cell transformation by the dbl oncogene.
    Morley S, Wagner J, Kauppinen K, Sherman M, Manor D.
    Cell Signal; 2007 Jan 17; 19(1):211-8. PubMed ID: 16916597
    [Abstract] [Full Text] [Related]

  • 16. Understanding the catalytic mechanism of GTPase-activating proteins: demonstration of the importance of switch domain stabilization in the stimulation of GTP hydrolysis.
    Fidyk NJ, Cerione RA.
    Biochemistry; 2002 Dec 31; 41(52):15644-53. PubMed ID: 12501193
    [Abstract] [Full Text] [Related]

  • 17. Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
    Nassar N, Hoffman GR, Manor D, Clardy JC, Cerione RA.
    Nat Struct Biol; 1998 Dec 31; 5(12):1047-52. PubMed ID: 9846874
    [Abstract] [Full Text] [Related]

  • 18. Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth.
    Miyamoto Y, Yamauchi J, Sanbe A, Tanoue A.
    Exp Cell Res; 2007 Feb 15; 313(4):791-804. PubMed ID: 17196961
    [Abstract] [Full Text] [Related]

  • 19. MEGAP impedes cell migration via regulating actin and microtubule dynamics and focal complex formation.
    Yang Y, Marcello M, Endris V, Saffrich R, Fischer R, Trendelenburg MF, Sprengel R, Rappold G.
    Exp Cell Res; 2006 Jul 15; 312(12):2379-93. PubMed ID: 16730001
    [Abstract] [Full Text] [Related]

  • 20. [Inhibition of ras-dependent transformation by using dominant negative ras mutant N116Y].
    Yokoyama T.
    Hokkaido Igaku Zasshi; 1995 May 15; 70(3):459-71. PubMed ID: 7590597
    [Abstract] [Full Text] [Related]


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