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432 related items for PubMed ID: 16785233

  • 1. Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.
    He X, Chen MG, Lin GX, Ma Q.
    J Biol Chem; 2006 Aug 18; 281(33):23620-31. PubMed ID: 16785233
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  • 2. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
    Kaspar JW, Niture SK, Jaiswal AK.
    J Cell Sci; 2012 Feb 15; 125(Pt 4):1027-38. PubMed ID: 22448038
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  • 4. Activation of Nrf2 in defense against cadmium-induced oxidative stress.
    He X, Chen MG, Ma Q.
    Chem Res Toxicol; 2008 Jul 15; 21(7):1375-83. PubMed ID: 18512965
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  • 8. NAD(P)H:quinone oxidoreductase 1 activity reduces hypertrophy in 3T3-L1 adipocytes.
    Vomhof-DeKrey EE, Picklo MJ.
    Free Radic Biol Med; 2012 Aug 15; 53(4):690-700. PubMed ID: 22683604
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  • 9. Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap 'n' collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2): cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduction.
    Ma Q, Kinneer K, Bi Y, Chan JY, Kan YW.
    Biochem J; 2004 Jan 01; 377(Pt 1):205-13. PubMed ID: 14510636
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  • 10. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.
    Zhang DD, Lo SC, Sun Z, Habib GM, Lieberman MW, Hannink M.
    J Biol Chem; 2005 Aug 26; 280(34):30091-9. PubMed ID: 15983046
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  • 11. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
    Furukawa M, Xiong Y.
    Mol Cell Biol; 2005 Jan 26; 25(1):162-71. PubMed ID: 15601839
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  • 16. Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.
    Katsuoka F, Motohashi H, Ishii T, Aburatani H, Engel JD, Yamamoto M.
    Mol Cell Biol; 2005 Sep 26; 25(18):8044-51. PubMed ID: 16135796
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  • 17. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
    Kobayashi A, Kang MI, Okawa H, Ohtsuji M, Zenke Y, Chiba T, Igarashi K, Yamamoto M.
    Mol Cell Biol; 2004 Aug 26; 24(16):7130-9. PubMed ID: 15282312
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  • 18. KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.
    Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD.
    Mol Cell Biol; 2011 May 26; 31(9):1800-11. PubMed ID: 21383067
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  • 19. Activation of NRF2 pathway in spleen, thymus as well as peripheral blood mononuclear cells by acute arsenic exposure in mice.
    Duan X, Li J, Zhang Y, Li W, Zhao L, Nie H, Sun G, Li B.
    Int Immunopharmacol; 2015 Oct 26; 28(2):1059-67. PubMed ID: 26371860
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  • 20. NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation.
    He X, Ma Q.
    Mol Pharmacol; 2009 Dec 26; 76(6):1265-78. PubMed ID: 19786557
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