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Journal Abstract Search

140 related items for PubMed ID: 16786270

  • 1. A novel dual peroxisome proliferator-activated receptors alpha and gamma agonist with beneficial effects on insulin resistance and lipid metabolism.
    Xu C, Wang LL, Liu HY, Ruan CM, Zhou XB, Cao YL, Li S.
    Biotechnol Lett; 2006 Jun; 28(12):863-8. PubMed ID: 16786270
    [Abstract] [Full Text] [Related]

  • 2. C333H, a novel PPARalpha/gamma dual agonist, has beneficial effects on insulin resistance and lipid metabolism.
    Xu C, Wang LL, Liu HY, Zhou XB, Cao YL, Li S.
    Acta Pharmacol Sin; 2006 Feb; 27(2):223-8. PubMed ID: 16412273
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  • 3. A nonthiazolidinedione peroxisome proliferator-activated receptor α/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice.
    Jeong HW, Lee JW, Kim WS, Choe SS, Shin HJ, Lee GY, Shin D, Lee JH, Choi EB, Lee HK, Yon GH, Cho B, Kim HR, Choi SH, Chung YS, Park SB, Chung H, Ro S, Kim JB.
    Mol Pharmacol; 2010 Nov; 78(5):877-85. PubMed ID: 20724462
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  • 4. PAR-5359, a well-balanced PPARalpha/gamma dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo.
    Kim MK, Chae YN, Son MH, Kim SH, Kim JK, Moon HS, Park CS, Bae MH, Kim E, Han T, Choi HH, Shin YA, Ahn BN, Lee CH, Lim JI, Shin CY.
    Eur J Pharmacol; 2008 Oct 24; 595(1-3):119-25. PubMed ID: 18727927
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  • 5. Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARgamma activation.
    Takahashi N, Goto T, Taimatsu A, Egawa K, Katoh S, Kusudo T, Sakamoto T, Ohyane C, Lee JY, Kim YI, Uemura T, Hirai S, Kawada T.
    Biochem Biophys Res Commun; 2009 Dec 25; 390(4):1372-6. PubMed ID: 19891958
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  • 6. Design and synthesis of N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a novel peroxisome proliferator-activated receptor alpha/gamma dual agonist with efficacious glucose and lipid-lowering activities.
    Devasthale PV, Chen S, Jeon Y, Qu F, Shao C, Wang W, Zhang H, Cap M, Farrelly D, Golla R, Grover G, Harrity T, Ma Z, Moore L, Ren J, Seethala R, Cheng L, Sleph P, Sun W, Tieman A, Wetterau JR, Doweyko A, Chandrasena G, Chang SY, Humphreys WG, Sasseville VG, Biller SA, Ryono DE, Selan F, Hariharan N, Cheng PT.
    J Med Chem; 2005 Mar 24; 48(6):2248-50. PubMed ID: 15771468
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  • 8. Peroxisome proliferator-activated receptor-alpha,gamma-agonist improves insulin sensitivity and prevents loss of left ventricular function in obese dyslipidemic mice.
    Verreth W, Ganame J, Mertens A, Bernar H, Herregods MC, Holvoet P.
    Arterioscler Thromb Vasc Biol; 2006 Apr 24; 26(4):922-8. PubMed ID: 16456093
    [Abstract] [Full Text] [Related]

  • 9. Biochemical mechanism of insulin sensitization, lipid modulation and anti-atherogenic potential of PPAR alpha/gamma dual agonist: Ragaglitazar.
    Sharma S, Sowjanya A, Kumari M, Suryaprakash R, Cynthia G, Suresh J, Chakrabarti R.
    Life Sci; 2006 Dec 23; 80(3):235-44. PubMed ID: 17014868
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  • 10. PPARalpha and PPARgamma dual agonists for the treatment of type 2 diabetes and the metabolic syndrome.
    Fiévet C, Fruchart JC, Staels B.
    Curr Opin Pharmacol; 2006 Dec 23; 6(6):606-14. PubMed ID: 16973418
    [Abstract] [Full Text] [Related]

  • 11. PAR-1622 is a selective peroxisome proliferator-activated receptor gamma partial activator with preserved antidiabetic efficacy and broader safety profile for fluid retention.
    Kim MK, Chae YN, Kim HS, Choi SH, Son MH, Kim SH, Kim JK, Moon HS, Park SK, Shin YA, Kim JG, Lee CH, Lim JI, Shin CY.
    Arch Pharm Res; 2009 May 23; 32(5):721-7. PubMed ID: 19471887
    [Abstract] [Full Text] [Related]

  • 12. Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice.
    Cha DR, Zhang X, Zhang Y, Wu J, Su D, Han JY, Fang X, Yu B, Breyer MD, Guan Y.
    Diabetes; 2007 Aug 23; 56(8):2036-45. PubMed ID: 17536062
    [Abstract] [Full Text] [Related]

  • 13. Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.
    Han KL, Choi JS, Lee JY, Song J, Joe MK, Jung MH, Hwang JK.
    Diabetes; 2008 Mar 23; 57(3):737-45. PubMed ID: 18065517
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  • 16. A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis.
    Leisewitz AV, Urrutia CR, Martinez GR, Loyola G, Bronfman M.
    J Cell Physiol; 2008 Nov 23; 217(2):367-76. PubMed ID: 18543250
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  • 17. 18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice.
    Anandharajan R, Sayyed SG, Doshi LS, Dixit P, Chandak PG, Dixit AV, Brahma MK, Deshmukh NJ, Gupte R, Damre A, Suthar J, Padigaru M, Sharma SD, Nemmani KV.
    Metabolism; 2009 Oct 23; 58(10):1503-16. PubMed ID: 19608207
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  • 19. Peroxisome proliferator-activated receptor gamma and the regulation of adipocyte function: lessons from human genetic studies.
    Gurnell M.
    Best Pract Res Clin Endocrinol Metab; 2005 Dec 23; 19(4):501-23. PubMed ID: 16311214
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  • 20. Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity.
    Pinelli A, Godio C, Laghezza A, Mitro N, Fracchiolla G, Tortorella V, Lavecchia A, Novellino E, Fruchart JC, Staels B, Crestani M, Loiodice F.
    J Med Chem; 2005 Aug 25; 48(17):5509-19. PubMed ID: 16107150
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