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Journal Abstract Search

271 related items for PubMed ID: 16788980

  • 21. Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents.
    Lai MJ, Kuo CC, Yeh TK, Hsieh HP, Chen LT, Pan WY, Hsu KY, Chang JY, Liou JP.
    ChemMedChem; 2009 Apr; 4(4):588-93. PubMed ID: 19266513
    [Abstract] [Full Text] [Related]

  • 22. Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents.
    Kamal A, Suresh P, Mallareddy A, Kumar BA, Reddy PV, Raju P, Tamboli JR, Shaik TB, Jain N, Kalivendi SV.
    Bioorg Med Chem; 2011 Apr 01; 19(7):2349-58. PubMed ID: 21402478
    [Abstract] [Full Text] [Related]

  • 23. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
    Ouyang X, Chen X, Piatnitski EL, Kiselyov AS, He HY, Mao Y, Pattaropong V, Yu Y, Kim KH, Kincaid J, Smith L, Wong WC, Lee SP, Milligan DL, Malikzay A, Fleming J, Gerlak J, Deevi D, Doody JF, Chiang HH, Patel SN, Wang Y, Rolser RL, Kussie P, Labelle M, Tuma MC.
    Bioorg Med Chem Lett; 2005 Dec 01; 15(23):5154-9. PubMed ID: 16198562
    [Abstract] [Full Text] [Related]

  • 24. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
    Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1191-6. PubMed ID: 16377187
    [Abstract] [Full Text] [Related]

  • 25. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
    Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E.
    Bioorg Med Chem; 2008 May 15; 16(10):5367-76. PubMed ID: 18440234
    [Abstract] [Full Text] [Related]

  • 26. Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors.
    Liou JP, Wu ZY, Kuo CC, Chang CY, Lu PY, Chen CM, Hsieh HP, Chang JY.
    J Med Chem; 2008 Jul 24; 51(14):4351-5. PubMed ID: 18588280
    [Abstract] [Full Text] [Related]

  • 27. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
    Chiang YK, Kuo CC, Wu YS, Chen CT, Coumar MS, Wu JS, Hsieh HP, Chang CY, Jseng HY, Wu MH, Leou JS, Song JS, Chang JY, Lyu PC, Chao YS, Wu SY.
    J Med Chem; 2009 Jul 23; 52(14):4221-33. PubMed ID: 19507860
    [Abstract] [Full Text] [Related]

  • 28. Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-alpha]isoquinoline derivatives.
    Goldbrunner M, Loidl G, Polossek T, Mannschreck A, von Angerer E.
    J Med Chem; 1997 Oct 24; 40(22):3524-33. PubMed ID: 9357519
    [Abstract] [Full Text] [Related]

  • 29. [Progress in the study of tubulin inhibitors].
    Shang H, Pan L, Yang S, Chen H, Cheng MS.
    Yao Xue Xue Bao; 2010 Sep 24; 45(9):1078-88. PubMed ID: 21351562
    [Abstract] [Full Text] [Related]

  • 30. Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines.
    Mahboobi S, Sellmer A, Eichhorn E, Beckers T, Fiebig HH, Kelter G.
    Eur J Med Chem; 2005 Jan 24; 40(1):85-92. PubMed ID: 15642413
    [Abstract] [Full Text] [Related]

  • 31. 7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents.
    Chang JY, Hsieh HP, Chang CY, Hsu KS, Chiang YF, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Nov 16; 49(23):6656-9. PubMed ID: 17154496
    [Abstract] [Full Text] [Related]

  • 32. Synthesis and biological evaluation of new disubstituted analogues of 6-methoxy-3-(3',4',5'-trimethoxybenzoyl)-1H-indole (BPR0L075), as potential antivascular agents.
    Ty N, Dupeyre G, Chabot GG, Seguin J, Tillequin F, Scherman D, Michel S, Cachet X.
    Bioorg Med Chem; 2008 Aug 01; 16(15):7494-503. PubMed ID: 18583138
    [Abstract] [Full Text] [Related]

  • 33. Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin.
    Bhattacharyya B, Panda D, Gupta S, Banerjee M.
    Med Res Rev; 2008 Jan 01; 28(1):155-83. PubMed ID: 17464966
    [Abstract] [Full Text] [Related]

  • 34. Antimitotic activity of lobaric acid and a new benzofuran, sakisacaulon A from Stereocaulon sasakii.
    Morita H, Tsuchiya T, Kishibe K, Noya S, Shiro M, Hirasawa Y.
    Bioorg Med Chem Lett; 2009 Jul 01; 19(13):3679-81. PubMed ID: 19481447
    [Abstract] [Full Text] [Related]

  • 35. Histone deacetylase and microtubules as targets for the synthesis of releasable conjugate compounds.
    Passarella D, Comi D, Vanossi A, Paganini G, Colombo F, Ferrante L, Zuco V, Danieli B, Zunino F.
    Bioorg Med Chem Lett; 2009 Nov 15; 19(22):6358-63. PubMed ID: 19833515
    [Abstract] [Full Text] [Related]

  • 36. A thalidomide analogue with in vitro antiproliferative, antimitotic, and microtubule-stabilizing activities.
    Li PK, Pandit B, Sackett DL, Hu Z, Zink J, Zhi J, Freeman D, Robey RW, Werbovetz K, Lewis A, Li C.
    Mol Cancer Ther; 2006 Feb 15; 5(2):450-6. PubMed ID: 16505120
    [Abstract] [Full Text] [Related]

  • 37. Structure-activity relationships of indole compounds derived from combretastatin A4: synthesis and biological screening of 5-phenylpyrrolo[3,4-a]carbazole-1,3-diones as potential antivascular agents.
    Ty N, Dupeyre G, Chabot GG, Seguin J, Quentin L, Chiaroni A, Tillequin F, Scherman D, Michel S, Cachet X.
    Eur J Med Chem; 2010 Sep 15; 45(9):3726-39. PubMed ID: 20538383
    [Abstract] [Full Text] [Related]

  • 38. Novel benzopyridothiadiazepines as potential active antitumor agents.
    Lebegue N, Gallet S, Flouquet N, Carato P, Pfeiffer B, Renard P, Léonce S, Pierré A, Chavatte P, Berthelot P.
    J Med Chem; 2005 Nov 17; 48(23):7363-73. PubMed ID: 16279796
    [Abstract] [Full Text] [Related]

  • 39. Interactions of antimitotic peptides and depsipeptides with tubulin.
    Hamel E.
    Biopolymers; 2002 Nov 17; 66(3):142-60. PubMed ID: 12385035
    [Abstract] [Full Text] [Related]

  • 40. Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment.
    Yamashita A, Norton EB, Kaplan JA, Niu C, Loganzo F, Hernandez R, Beyer CF, Annable T, Musto S, Discafani C, Zask A, Ayral-Kaloustian S.
    Bioorg Med Chem Lett; 2004 Nov 01; 14(21):5317-22. PubMed ID: 15454219
    [Abstract] [Full Text] [Related]

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