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222 related items for PubMed ID: 16804563

  • 1. Downregulation of uPA, uPAR and MMP-9 using small, interfering, hairpin RNA (siRNA) inhibits glioma cell invasion, angiogenesis and tumor growth.
    Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Neuron Glia Biol; 2004 May; 1(2):165-76. PubMed ID: 16804563
    [Abstract] [Full Text] [Related]

  • 2. Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas.
    Lakka SS, Gondi CS, Dinh DH, Olivero WC, Gujrati M, Rao VH, Sioka C, Rao JS.
    J Biol Chem; 2005 Jun 10; 280(23):21882-92. PubMed ID: 15824107
    [Abstract] [Full Text] [Related]

  • 3. Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.
    Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Clin Cancer Res; 2007 Jul 15; 13(14):4051-60. PubMed ID: 17634529
    [Abstract] [Full Text] [Related]

  • 4. Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth.
    Lakka SS, Gondi CS, Yanamandra N, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Cancer Res; 2003 May 15; 63(10):2454-61. PubMed ID: 12750266
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis.
    Lakka SS, Gondi CS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Rao JS.
    Oncogene; 2004 Jun 10; 23(27):4681-9. PubMed ID: 15122332
    [Abstract] [Full Text] [Related]

  • 6. RNAi-mediated inhibition of cathepsin B and uPAR leads to decreased cell invasion, angiogenesis and tumor growth in gliomas.
    Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Oncogene; 2004 Nov 04; 23(52):8486-96. PubMed ID: 15378018
    [Abstract] [Full Text] [Related]

  • 7. Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.
    Gondi CS, Lakka SS, Yanamandra N, Siddique K, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Oncogene; 2003 Sep 04; 22(38):5967-75. PubMed ID: 12955075
    [Abstract] [Full Text] [Related]

  • 8. Simultaneous downregulation of uPAR and MMP-9 induces overexpression of the FADD-associated protein RIP and activates caspase 9-mediated apoptosis in gliomas.
    Gondi CS, Dinh DH, Gujrati M, Rao JS.
    Int J Oncol; 2008 Oct 04; 33(4):783-90. PubMed ID: 18813792
    [Abstract] [Full Text] [Related]

  • 9. RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth.
    Kondraganti S, Gondi CS, McCutcheon I, Dinh DH, Gujrati M, Rao JS, Olivero WC.
    Int J Oncol; 2006 Jun 04; 28(6):1353-60. PubMed ID: 16685436
    [Abstract] [Full Text] [Related]

  • 10. siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells.
    Subramanian R, Gondi CS, Lakka SS, Jutla A, Rao JS.
    Int J Oncol; 2006 Apr 04; 28(4):831-9. PubMed ID: 16525631
    [Abstract] [Full Text] [Related]

  • 11. In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor.
    Mohanam S, Chintala SK, Go Y, Bhattacharya A, Venkaiah B, Boyd D, Gokaslan ZL, Sawaya R, Rao JS.
    Oncogene; 1997 Mar 20; 14(11):1351-9. PubMed ID: 9178895
    [Abstract] [Full Text] [Related]

  • 12. RNA interference-mediated targeting of urokinase plasminogen activator receptor and matrix metalloproteinase-9 gene expression in the IOMM-lee malignant meningioma cell line inhibits tumor growth, tumor cell invasion and angiogenesis.
    Tummalapalli P, Gondi CS, Dinh DH, Gujrati M, Rao JS.
    Int J Oncol; 2007 Jul 20; 31(1):5-17. PubMed ID: 17549400
    [Abstract] [Full Text] [Related]

  • 13. Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells.
    Mohanam S, Jasti SL, Kondraganti SR, Chandrasekar N, Kin Y, Fuller GN, Lakka SS, Kyritsis AP, Dinh DH, Olivero WC, Gujrati M, Yung WK, Rao JS.
    Clin Cancer Res; 2001 Aug 20; 7(8):2519-26. PubMed ID: 11489835
    [Abstract] [Full Text] [Related]

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  • 16. Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells.
    Rao JS, Gondi C, Chetty C, Chittivelu S, Joseph PA, Lakka SS.
    Mol Cancer Ther; 2005 Sep 20; 4(9):1399-408. PubMed ID: 16170032
    [Abstract] [Full Text] [Related]

  • 17. [Mechanism of tumor cell-induced extracellular matrix degradation--inhibition of cell-surface proteolytic activity might have a therapeutic effect on tumor cell invasion and metastasis].
    Kobayashi H.
    Nihon Sanka Fujinka Gakkai Zasshi; 1996 Aug 20; 48(8):623-32. PubMed ID: 8808830
    [Abstract] [Full Text] [Related]

  • 18. Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas.
    Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Tung CH, Weissleder R, Rao JS.
    Cancer Res; 2004 Jun 15; 64(12):4069-77. PubMed ID: 15205313
    [Abstract] [Full Text] [Related]

  • 19. uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo.
    Kargiotis O, Chetty C, Gogineni V, Gondi CS, Pulukuri SM, Kyritsis AP, Gujrati M, Klopfenstein JD, Dinh DH, Rao JS.
    Int J Oncol; 2008 Nov 15; 33(5):937-47. PubMed ID: 18949356
    [Abstract] [Full Text] [Related]

  • 20. MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice.
    Veeravalli KK, Chetty C, Ponnala S, Gondi CS, Lakka SS, Fassett D, Klopfenstein JD, Dinh DH, Gujrati M, Rao JS.
    PLoS One; 2010 Jul 15; 5(7):e11583. PubMed ID: 20657647
    [Abstract] [Full Text] [Related]


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