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2082 related items for PubMed ID: 16818631

  • 1. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
    Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ.
    Cancer Res; 2006 Jul 01; 66(13):6589-97. PubMed ID: 16818631
    [Abstract] [Full Text] [Related]

  • 2. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.
    Oncogene; 2007 Aug 16; 26(38):5606-14. PubMed ID: 17353907
    [Abstract] [Full Text] [Related]

  • 3. Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma.
    Peponi E, Drakos E, Reyes G, Leventaki V, Rassidakis GZ, Medeiros LJ.
    Am J Pathol; 2006 Dec 16; 169(6):2171-80. PubMed ID: 17148679
    [Abstract] [Full Text] [Related]

  • 4. Prognostic significance and therapeutic potential of the activation of anaplastic lymphoma kinase/protein kinase B/mammalian target of rapamycin signaling pathway in anaplastic large cell lymphoma.
    Gao J, Yin M, Zhu Y, Gu L, Zhang Y, Li Q, Jia C, Ma Z.
    BMC Cancer; 2013 Oct 10; 13():471. PubMed ID: 24112608
    [Abstract] [Full Text] [Related]

  • 5. Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway.
    Bai RY, Ouyang T, Miething C, Morris SW, Peschel C, Duyster J.
    Blood; 2000 Dec 15; 96(13):4319-27. PubMed ID: 11110708
    [Abstract] [Full Text] [Related]

  • 6. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T, Nishioka C, Bandobashi K, Yang Y, Kuwayama Y, Adachi Y, Takeuchi T, Koeffler HP, Taguchi H.
    Leuk Res; 2007 May 15; 31(5):673-82. PubMed ID: 17007924
    [Abstract] [Full Text] [Related]

  • 7. [Study on activation of AKT/mTOR pathway in anaplastic large cell lymphoma].
    Li JF, Li GD, Gu L, Liu WP, Li FY, Liao DY, Ma ZG.
    Zhonghua Xue Ye Xue Za Zhi; 2008 Oct 15; 29(10):649-53. PubMed ID: 19176054
    [Abstract] [Full Text] [Related]

  • 8. Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
    Bishop JD, Nien WL, Dauphinee SM, Too CK.
    J Endocrinol; 2006 Aug 15; 190(2):307-12. PubMed ID: 16899564
    [Abstract] [Full Text] [Related]

  • 9. Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.
    Singh RR, Cho-Vega JH, Davuluri Y, Ma S, Kasbidi F, Milito C, Lennon PA, Drakos E, Medeiros LJ, Luthra R, Vega F.
    Cancer Res; 2009 Mar 15; 69(6):2550-8. PubMed ID: 19244133
    [Abstract] [Full Text] [Related]

  • 10. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
    Han S, Khuri FR, Roman J.
    Cancer Res; 2006 Jan 01; 66(1):315-23. PubMed ID: 16397245
    [Abstract] [Full Text] [Related]

  • 11. NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma.
    Leventaki V, Drakos E, Medeiros LJ, Lim MS, Elenitoba-Johnson KS, Claret FX, Rassidakis GZ.
    Blood; 2007 Sep 01; 110(5):1621-30. PubMed ID: 17416736
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
    Tsurutani J, West KA, Sayyah J, Gills JJ, Dennis PA.
    Cancer Res; 2005 Sep 15; 65(18):8423-32. PubMed ID: 16166321
    [Abstract] [Full Text] [Related]

  • 13. The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration.
    Voena C, Conte C, Ambrogio C, Boeri Erba E, Boccalatte F, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R.
    Cancer Res; 2007 May 01; 67(9):4278-86. PubMed ID: 17483340
    [Abstract] [Full Text] [Related]

  • 14. NPM/ALK downregulates p27Kip1 in a PI-3K-dependent manner.
    Slupianek A, Skorski T.
    Exp Hematol; 2004 Dec 01; 32(12):1265-71. PubMed ID: 15588951
    [Abstract] [Full Text] [Related]

  • 15. Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis.
    Gu L, Gao J, Li Q, Zhu YP, Jia CS, Fu RY, Chen Y, Liao QK, Ma Z.
    Leukemia; 2008 Nov 01; 22(11):2091-6. PubMed ID: 18685609
    [Abstract] [Full Text] [Related]

  • 16. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
    Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH.
    Am J Physiol Cell Physiol; 2004 Aug 01; 287(2):C281-91. PubMed ID: 15028555
    [Abstract] [Full Text] [Related]

  • 17. Concurrent inhibition of PI3-kinase and mTOR induces cell death in diffuse large B cell lymphomas, a mechanism involving down regulation of Mcl-1.
    Zang C, Eucker J, Liu H, Müller A, Possinger K, Scholz CW.
    Cancer Lett; 2013 Oct 10; 339(2):288-97. PubMed ID: 23200668
    [Abstract] [Full Text] [Related]

  • 18. Biochemical differences between SUDHL-1 and KARPAS 299 cells derived from t(2;5)-positive anaplastic large cell lymphoma are responsible for the different sensitivity to the antiproliferative effect of p27(Kip1).
    Turturro F, Frist AY, Arnold MD, Seth P, Pulford K.
    Oncogene; 2001 Jul 27; 20(33):4466-75. PubMed ID: 11494142
    [Abstract] [Full Text] [Related]

  • 19. Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR.
    Dutton A, Reynolds GM, Dawson CW, Young LS, Murray PG.
    J Pathol; 2005 Mar 27; 205(4):498-506. PubMed ID: 15714459
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma.
    Rassidakis GZ, Feretzaki M, Atwell C, Grammatikakis I, Lin Q, Lai R, Claret FX, Medeiros LJ, Amin HM.
    Blood; 2005 Jan 15; 105(2):827-9. PubMed ID: 15374880
    [Abstract] [Full Text] [Related]

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