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396 related items for PubMed ID: 1681900

  • 1. Identification of the ATP binding sites of the carbamyl phosphate synthetase domain of the Syrian hamster multifunctional protein CAD by affinity labeling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
    Kim HS, Lee L, Evans DR.
    Biochemistry; 1991 Oct 22; 30(42):10322-9. PubMed ID: 1681900
    [Abstract] [Full Text] [Related]

  • 2. Identification of the regulatory domain of the mammalian multifunctional protein CAD by the construction of an Escherichia coli hamster hybrid carbamyl-phosphate synthetase.
    Liu X, Guy HI, Evans DR.
    J Biol Chem; 1994 Nov 04; 269(44):27747-55. PubMed ID: 7525561
    [Abstract] [Full Text] [Related]

  • 3. Trapping an activated conformation of mammalian carbamyl-phosphate synthetase.
    Guy HI, Evans DR.
    J Biol Chem; 1997 Aug 08; 272(32):19906-12. PubMed ID: 9242656
    [Abstract] [Full Text] [Related]

  • 4. Functional linkage between the glutaminase and synthetase domains of carbamoyl-phosphate synthetase. Role of serine 44 in carbamoyl-phosphate synthetase-aspartate carbamoyltransferase-dihydroorotase (cad).
    Hewagama A, Guy HI, Vickrey JF, Evans DR.
    J Biol Chem; 1999 Oct 01; 274(40):28240-5. PubMed ID: 10497179
    [Abstract] [Full Text] [Related]

  • 5. Autophosphorylation of the mammalian multifunctional protein that initiates de novo pyrimidine biosynthesis.
    Sigoillot FD, Evans DR, Guy HI.
    J Biol Chem; 2002 Jul 05; 277(27):24809-17. PubMed ID: 11986331
    [Abstract] [Full Text] [Related]

  • 6. Immunochemical analysis of the domain structure of CAD, the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells.
    Grayson DR, Lee L, Evans DR.
    J Biol Chem; 1985 Dec 15; 260(29):15840-9. PubMed ID: 2866187
    [Abstract] [Full Text] [Related]

  • 7. Allosteric regulation and substrate channeling in multifunctional pyrimidine biosynthetic complexes: analysis of isolated domains and yeast-mammalian chimeric proteins.
    Serre V, Guy H, Liu X, Penverne B, Hervé G, Evans D.
    J Mol Biol; 1998 Aug 14; 281(2):363-77. PubMed ID: 9698553
    [Abstract] [Full Text] [Related]

  • 8. The catalytic mechanism of the amidotransferase domain of the Syrian hamster multifunctional protein CAD. Evidence for a CAD-glutamyl covalent intermediate in the formation of carbamyl phosphate.
    Chaparian MG, Evans DR.
    J Biol Chem; 1991 Feb 25; 266(6):3387-95. PubMed ID: 1671673
    [Abstract] [Full Text] [Related]

  • 9. Mammalian carbamyl phosphate synthetase (CPS). DNA sequence and evolution of the CPS domain of the Syrian hamster multifunctional protein CAD.
    Simmer JP, Kelly RE, Rinker AG, Scully JL, Evans DR.
    J Biol Chem; 1990 Jun 25; 265(18):10395-402. PubMed ID: 1972379
    [Abstract] [Full Text] [Related]

  • 10. Regulation of carbamoyl phosphate synthetase by MAP kinase.
    Graves LM, Guy HI, Kozlowski P, Huang M, Lazarowski E, Pope RM, Collins MA, Dahlstrand EN, Earp HS, Evans DR.
    Nature; 2000 Jan 20; 403(6767):328-32. PubMed ID: 10659854
    [Abstract] [Full Text] [Related]

  • 11. Proteolytic cleavage of the multienzyme polypeptide CAD to release the mammalian aspartate transcarbamoylase. Biochemical comparison with the homologous Escherichia coli catalytic subunit.
    Hemmens B, Carrey EA.
    Eur J Biochem; 1994 Nov 01; 225(3):845-53. PubMed ID: 7957221
    [Abstract] [Full Text] [Related]

  • 12. Phosphorylation and activation of hamster carbamyl phosphate synthetase II by cAMP-dependent protein kinase. A novel mechanism for regulation of pyrimidine nucleotide biosynthesis.
    Carrey EA, Campbell DG, Hardie DG.
    EMBO J; 1985 Dec 30; 4(13B):3735-42. PubMed ID: 4092695
    [Abstract] [Full Text] [Related]

  • 13. The dihydroorotase domain of the multifunctional protein CAD. Subunit structure, zinc content, and kinetics.
    Kelly RE, Mally MI, Evans DR.
    J Biol Chem; 1986 May 05; 261(13):6073-83. PubMed ID: 2871022
    [Abstract] [Full Text] [Related]

  • 14. Mapping of catalytic domains and phosphorylation sites in the multifunctional pyrimidine-biosynthetic protein CAD.
    Carrey EA, Hardie DG.
    Eur J Biochem; 1988 Feb 01; 171(3):583-8. PubMed ID: 3345746
    [Abstract] [Full Text] [Related]

  • 15. Affinity labeling of rat liver carbamyl phosphate synthetase I by 5'-p-fluorosulfonylbenzoyladenosine.
    Powers SG, Muller GW, Kafka N.
    J Biol Chem; 1983 Jun 25; 258(12):7545-9. PubMed ID: 6863253
    [Abstract] [Full Text] [Related]

  • 16. The overall synthesis of L-5,6-dihydroorotate by multienzymatic protein pyr1-3 from hamster cells. Kinetic studies, substrate channeling, and the effects of inhibitors.
    Christopherson RI, Jones ME.
    J Biol Chem; 1980 Dec 10; 255(23):11381-95. PubMed ID: 6108323
    [Abstract] [Full Text] [Related]

  • 17. Identification of the junction between the glutamine amidotransferase and carbamyl phosphate synthetase domains of the mammalian CAD protein.
    Maley JA, Davidson JN.
    Biochem Biophys Res Commun; 1988 Aug 15; 154(3):1047-53. PubMed ID: 2900634
    [Abstract] [Full Text] [Related]

  • 18. Cloning, expression, and functional interactions of the amidotransferase domain of mammalian CAD carbamyl phosphate synthetase.
    Guy HI, Evans DR.
    J Biol Chem; 1994 Mar 11; 269(10):7702-8. PubMed ID: 7907330
    [Abstract] [Full Text] [Related]

  • 19. The structural organization of the hamster multifunctional protein CAD. Controlled proteolysis, domains, and linkers.
    Kim H, Kelly RE, Evans DR.
    J Biol Chem; 1992 Apr 05; 267(10):7177-84. PubMed ID: 1348059
    [Abstract] [Full Text] [Related]

  • 20. Location of the ATP gamma-phosphate-binding sites on rat liver carbamoyl-phosphate synthetase I. Studies with the ATP analog 5'-p-fluorosulfonylbenzoyladenosine.
    Potter MD, Powers-Lee SG.
    J Biol Chem; 1992 Jan 25; 267(3):2023-31. PubMed ID: 1730733
    [Abstract] [Full Text] [Related]

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