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Journal Abstract Search

341 related items for PubMed ID: 16820225

  • 1. Rational design of polymerase inhibitors as antiviral drugs.
    Oberg B.
    Antiviral Res; 2006 Sep; 71(2-3):90-5. PubMed ID: 16820225
    [Abstract] [Full Text] [Related]

  • 2. The antiviral activity and mechanism of action of (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] (HPMP) nucleosides.
    Magee WC, Evans DH.
    Antiviral Res; 2012 Nov; 96(2):169-80. PubMed ID: 22960154
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  • 7. All-atom models for the non-nucleoside binding site of HIV-1 reverse transcriptase complexed with inhibitors: a 3D QSAR approach.
    Gussio R, Pattabiraman N, Zaharevitz DW, Kellogg GE, Topol IA, Rice WG, Schaeffer CA, Erickson JW, Burt SK.
    J Med Chem; 1996 Apr 12; 39(8):1645-50. PubMed ID: 8648604
    [Abstract] [Full Text] [Related]

  • 8. Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase.
    Menéndez-Arias L.
    Virus Res; 2008 Jun 12; 134(1-2):124-46. PubMed ID: 18272247
    [Abstract] [Full Text] [Related]

  • 9. Alpha-carboxynucleoside phosphonates: direct-acting inhibitors of viral DNA polymerases.
    Balzarini J, Ford A, Maguire NM, John J, Das K, Arnold E, Dehaen W, Maguire A.
    Future Med Chem; 2019 Jan 12; 11(2):137-154. PubMed ID: 30648904
    [Abstract] [Full Text] [Related]

  • 10. Ring-expanded ("fat") nucleoside and nucleotide analogues exhibit potent in vitro activity against flaviviridae NTPases/helicases, including those of the West Nile virus, hepatitis C virus, and Japanese encephalitis virus.
    Zhang N, Chen HM, Koch V, Schmitz H, Liao CL, Bretner M, Bhadti VS, Fattom AI, Naso RB, Hosmane RS, Borowski P.
    J Med Chem; 2003 Sep 11; 46(19):4149-64. PubMed ID: 12954067
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  • 11. Mechanism of inhibition of HIV-1 reverse transcriptase by the novel broad-range DNA polymerase inhibitor N-{2-[4-(aminosulfonyl)phenyl]ethyl}-2-(2-thienyl)acetamide.
    Herschhorn A, Oz-Gleenberg I, Hizi A.
    Biochemistry; 2008 Jan 08; 47(1):490-502. PubMed ID: 18052256
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  • 12. Differential inhibitory effects of several pyrimidine 2',3'-dideoxynucleoside 5'-triphosphates on the activities of reverse transcriptase and various cellular DNA polymerases.
    Ono K, Nakane H, Herdewijn P, Balzarini J, De Clercq E.
    Mol Pharmacol; 1989 May 08; 35(5):578-83. PubMed ID: 2471054
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  • 13. Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
    O'Meara JA, Jakalian A, LaPlante S, Bonneau PR, Coulombe R, Faucher AM, Guse I, Landry S, Racine J, Simoneau B, Thavonekham B, Yoakim C.
    Bioorg Med Chem Lett; 2007 Jun 15; 17(12):3362-6. PubMed ID: 17451954
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  • 14. Antiviral drug discovery and development: where chemistry meets with biomedicine.
    De Clercq E.
    Antiviral Res; 2005 Aug 15; 67(2):56-75. PubMed ID: 16046240
    [Abstract] [Full Text] [Related]

  • 15. Non-nucleoside inhibitors of herpesviruses.
    Wathen MW.
    Rev Med Virol; 2002 Aug 15; 12(3):167-78. PubMed ID: 11987142
    [Abstract] [Full Text] [Related]

  • 16. Substrate/inhibition studies of bacteriophage T7 RNA polymerase with the 5'-triphosphate derivative of a ring-expanded ('fat') nucleoside possessing potent antiviral and anticancer activities.
    Bretner M, Beckett TD, Sood RK, Baldisseri DM, Hosmane RS.
    Bioorg Med Chem; 1999 Dec 15; 7(12):2931-6. PubMed ID: 10658598
    [Abstract] [Full Text] [Related]

  • 17. Strategies for antiviral drug discovery.
    Jones PS.
    Antivir Chem Chemother; 1998 Jul 15; 9(4):283-302. PubMed ID: 9875408
    [Abstract] [Full Text] [Related]

  • 18. Different inhibitory potencies of acyclic phosphonomethoxyalkyl nucleotide analogs toward DNA polymerases alpha, delta and epsilon.
    Kramata P, Votruba I, Otová B, Holý A.
    Mol Pharmacol; 1996 Jun 15; 49(6):1005-11. PubMed ID: 8649338
    [Abstract] [Full Text] [Related]

  • 19. [Interaction of HIV-1 reverse transcriptase and bacteriophage T7 RNA polymerase with NTP phosphonate analogs and inorganic pyrophosphate].
    Andreeva OI, Efimtseva EV, Padiukova NSh, Kochetkov SN, Mikhaĭlov SN, Dixon GB, Karpeĭskiĭ MIa.
    Mol Biol (Mosk); 2001 Jun 15; 35(5):844-56. PubMed ID: 11605538
    [Abstract] [Full Text] [Related]

  • 20. Design of nucleoside, oligonucleotide and polynucleotide analogues as antiviral agents.
    De Clercq E.
    Nucleic Acids Symp Ser; 1982 Jun 15; (11):203-6. PubMed ID: 6191285
    [Abstract] [Full Text] [Related]

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