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192 related items for PubMed ID: 16831299

  • 1. Role of FK778 alone or in combination with tacrolimus or mTOR inhibitors as an immunomodulator of immunofunctions: in vitro evaluation of T cell proliferation and the expression of lymphocyte surface antigens.
    Millán O, Jiménez O, Fortuna V, Barceló JJ, Brunet M.
    Int J Immunopathol Pharmacol; 2006; 19(2):317-30. PubMed ID: 16831299
    [Abstract] [Full Text] [Related]

  • 2. Combination therapy of malononitrilamide FK778 with tacrolimus on cell proliferation assays and in rats receiving renal allografts.
    Vu MD, Qi S, Wang X, Jiang W, Ma A, Xu D, Bekersky I, Fitzsimmons WE, Wu J, Chen H.
    Transplantation; 2003 May 15; 75(9):1455-9. PubMed ID: 12792496
    [Abstract] [Full Text] [Related]

  • 3. FK778 in experimental xenotransplantation: a detailed analysis of drug efficacy.
    Schrepfer S, Deuse T, Koch-Nolte F, Krieger T, Haddad M, Schäfer H, Pelletier MP, Robbins RC, Reichenspurner H.
    J Heart Lung Transplant; 2007 Jan 15; 26(1):70-7. PubMed ID: 17234520
    [Abstract] [Full Text] [Related]

  • 4. FK778: new cellular and molecular mechanisms of action.
    Schrepfer S, Deuse T, Koch-Nolte F, Detter C, Reichenspurner H.
    Transplant Proc; 2006 Apr 15; 38(3):757-61. PubMed ID: 16647464
    [Abstract] [Full Text] [Related]

  • 5. In vivo pharmacokinetic and pharmacodynamic evaluation of the malononitrilamide FK778 in non-human primates.
    Bîrsan T, Dambrin C, Klupp J, Stalder M, Larson MJ, Fitzsimmons WE, Morris RE.
    Transpl Int; 2003 May 15; 16(5):354-60. PubMed ID: 12712238
    [Abstract] [Full Text] [Related]

  • 6. FK778 and tacrolimus prevent the development of obliterative airway disease after heterotopic rat tracheal transplantation.
    Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schwedhelm E, Böger R, Schäfer H, Detter C, Reichenspurner H.
    J Heart Lung Transplant; 2005 Nov 15; 24(11):1844-54. PubMed ID: 16297791
    [Abstract] [Full Text] [Related]

  • 7. FK778 ameliorates post-transplant expression of fibrogenic growth factors and development of chronic rejection changes in rat kidney allografts.
    Rintala JM, Savikko J, Rintala SE, von Willebrand E.
    Nephrol Dial Transplant; 2008 Nov 15; 23(11):3446-55. PubMed ID: 18558624
    [Abstract] [Full Text] [Related]

  • 8. The influence of immunosuppressive drugs on T- and B-cell apoptosis via p53-mediated pathway in vitro and in vivo.
    Boldt A, Barten MJ, Sagner A, Mohr FW, Adams V, Dhein S, Gummert JF.
    Transplantation; 2006 Aug 15; 82(3):422-7. PubMed ID: 16906043
    [Abstract] [Full Text] [Related]

  • 9. Assessment of immunosuppressive drug interactions: inhibition of lymphocyte function in peripheral human blood.
    Barten MJ, Dhein S, Chang H, Bittner HB, Tarnok A, Rahmel A, Mohr FW, Gummert JF.
    J Immunol Methods; 2003 Dec 15; 283(1-2):99-114. PubMed ID: 14659903
    [Abstract] [Full Text] [Related]

  • 10. The novel immunosuppressant FK778 inhibits formation of the immunologic Synapse.
    Zeyda M, Geyeregger R, Poglitsch M, Watschinger B, Hörl WH, Stulnig TM, Säemann MD.
    Transplant Proc; 2005 May 15; 37(4):1970-1. PubMed ID: 15919521
    [Abstract] [Full Text] [Related]

  • 11. Susceptibility of human mesenchymal stem cells to tacrolimus, mycophenolic acid, and rapamycin.
    Hoogduijn MJ, Crop MJ, Korevaar SS, Peeters AM, Eijken M, Maat LP, Balk AH, Weimar W, Baan CC.
    Transplantation; 2008 Nov 15; 86(9):1283-91. PubMed ID: 19005411
    [Abstract] [Full Text] [Related]

  • 12. The effect of FK778 on acute rat renal allograft rejection and expression of platelet-derived growth factor and transforming growth factor-beta.
    Rintala JM, Savikko J, Rintala SE, von Willebrand E.
    Transplant Proc; 2006 Oct 15; 38(8):2719-21. PubMed ID: 17098049
    [Abstract] [Full Text] [Related]

  • 13. Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer.
    Boulay A, Rudloff J, Ye J, Zumstein-Mecker S, O'Reilly T, Evans DB, Chen S, Lane HA.
    Clin Cancer Res; 2005 Jul 15; 11(14):5319-28. PubMed ID: 16033851
    [Abstract] [Full Text] [Related]

  • 14. Pharmacodynamics of immunosuppression by mycophenolic acid: inhibition of both lymphocyte proliferation and activation correlates with pharmacokinetics.
    Gummert JF, Barten MJ, Sherwood SW, van Gelder T, Morris RE.
    J Pharmacol Exp Ther; 1999 Dec 15; 291(3):1100-12. PubMed ID: 10565830
    [Abstract] [Full Text] [Related]

  • 15. Effects of the malononitrilamide FK778 on immune functions in vitro in whole blood from non-human primates and healthy human volunteers.
    Bîrsan T, Dambrin C, Klupp J, Stalder M, Fitzsimmons WE, Morris RE.
    Transpl Immunol; 2003 Dec 15; 11(2):163-7. PubMed ID: 12799199
    [Abstract] [Full Text] [Related]

  • 16. Pharmacodynamic effects of everolimus on anti-CD3 antibody-stimulated T-lymphocyte proliferation and interleukin-10 synthesis in stable kidney-transplant patients.
    Böhler T, Waiser J, Lichter S, Schumann B, Neumayer HH, Kamar N, Budde K.
    Cytokine; 2008 Jun 15; 42(3):306-11. PubMed ID: 18440821
    [Abstract] [Full Text] [Related]

  • 17. The effect of leflunomide analogue FK778 on development of chronic rat renal allograft rejection and transforming growth factor-BETA expression.
    Rintala JM, Savikko J, Rintala SE, von Willebrand E.
    Transplant Proc; 2006 Dec 15; 38(10):3239-40. PubMed ID: 17175234
    [Abstract] [Full Text] [Related]

  • 18. Novel apoptosis assay to analyze immunosuppression.
    Boldt A, Barten MJ, Weiss C, Sagner A, Mohr FW, Gummert JF.
    Cytometry A; 2006 Mar 15; 69(3):158-60. PubMed ID: 16479615
    [Abstract] [Full Text] [Related]

  • 19. Evaluation for synergistic suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and a rapamycin derivative, SDZ-RAD.
    Hsiao CC, Su WN, Forooghian F, Bader S, Rempel J, HayGlass KT, Gilman A, Schultz KR.
    Bone Marrow Transplant; 2002 Dec 15; 30(12):905-13. PubMed ID: 12476284
    [Abstract] [Full Text] [Related]

  • 20. The new immunosuppressive agent FK778 attenuates neointima formation in an experimental venous bypass graft model.
    de Graaf R, Kloppenburg G, Tintu A, Rouwet E, Kitslaar P, van Hooff J, Bruggeman C, Stassen F.
    Vascul Pharmacol; 2009 Dec 15; 50(3-4):83-8. PubMed ID: 19010449
    [Abstract] [Full Text] [Related]

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