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278 related items for PubMed ID: 16835749

  • 1. The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells.
    Arredondo J, Chernyavsky AI, Grando SA.
    J Cancer Res Clin Oncol; 2006 Oct; 132(10):653-63. PubMed ID: 16835749
    [Abstract] [Full Text] [Related]

  • 2. Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells.
    Arredondo J, Chernyavsky AI, Grando SA.
    Cancer Biol Ther; 2006 May; 5(5):511-7. PubMed ID: 16582591
    [Abstract] [Full Text] [Related]

  • 3. The nicotinic acetylcholine receptor-mediated reciprocal effects of the tobacco nitrosamine NNK and SLURP-1 on human mammary epithelial cells.
    Kalantari-Dehaghi M, Parnell EA, Armand T, Bernard HU, Grando SA.
    Int Immunopharmacol; 2015 Nov; 29(1):99-104. PubMed ID: 25986726
    [Abstract] [Full Text] [Related]

  • 4. Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells.
    Schuller HM, Orloff M.
    Biochem Pharmacol; 1998 May 01; 55(9):1377-84. PubMed ID: 10076528
    [Abstract] [Full Text] [Related]

  • 5. The modulating role of nuclear factor-kappaB in the action of alpha7-nicotinic acetylcholine receptor and cross-talk between 5-lipoxygenase and cyclooxygenase-2 in colon cancer growth induced by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.
    Ye YN, Liu ES, Shin VY, Wu WK, Cho CH.
    J Pharmacol Exp Ther; 2004 Oct 01; 311(1):123-30. PubMed ID: 15161935
    [Abstract] [Full Text] [Related]

  • 6. Nicotinic receptor-mediated activation by the tobacco-specific nitrosamine NNK of a Raf-1/MAP kinase pathway, resulting in phosphorylation of c-myc in human small cell lung carcinoma cells and pulmonary neuroendocrine cells.
    Jull BA, Plummer HK, Schuller HM.
    J Cancer Res Clin Oncol; 2001 Dec 01; 127(12):707-17. PubMed ID: 11768610
    [Abstract] [Full Text] [Related]

  • 7. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the alpha7 nicotinic acetylcholine receptor/ERK signaling pathway.
    Hung YH, Hung WC.
    Chem Biol Interact; 2009 May 15; 179(2-3):154-9. PubMed ID: 19027725
    [Abstract] [Full Text] [Related]

  • 8. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways.
    Shin VY, Jin HC, Ng EK, Yu J, Leung WK, Cho CH, Sung JJ.
    Toxicol Appl Pharmacol; 2008 Dec 01; 233(2):254-61. PubMed ID: 18805435
    [Abstract] [Full Text] [Related]

  • 9. Comparative carcinogenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine in Syrian golden hamsters.
    Hoffmann D, Castonguay A, Rivenson A, Hecht SS.
    Cancer Res; 1981 Jun 01; 41(6):2386-93. PubMed ID: 7237437
    [Abstract] [Full Text] [Related]

  • 10. Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes.
    Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA.
    FASEB J; 2006 Oct 01; 20(12):2093-101. PubMed ID: 17012261
    [Abstract] [Full Text] [Related]

  • 11. Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke.
    Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA.
    FASEB J; 2008 May 01; 22(5):1356-68. PubMed ID: 18450646
    [Abstract] [Full Text] [Related]

  • 12. Basic and clinical aspects of non-neuronal acetylcholine: biological and clinical significance of non-canonical ligands of epithelial nicotinic acetylcholine receptors.
    Grando SA.
    J Pharmacol Sci; 2008 Feb 01; 106(2):174-9. PubMed ID: 18285656
    [Abstract] [Full Text] [Related]

  • 13. Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.
    Ho YS, Chen CH, Wang YJ, Pestell RG, Albanese C, Chen RJ, Chang MC, Jeng JH, Lin SY, Liang YC, Tseng H, Lee WS, Lin JK, Chu JS, Chen LC, Lee CH, Tso WL, Lai YC, Wu CH.
    Toxicol Appl Pharmacol; 2005 Jun 01; 205(2):133-48. PubMed ID: 15893541
    [Abstract] [Full Text] [Related]

  • 14. Long-term exposure to extremely low-dose of nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induce non-malignant breast epithelial cell transformation through activation of the a9-nicotinic acetylcholine receptor-mediated signaling pathway.
    Fararjeh AS, Tu SH, Chen LC, Cheng TC, Liu YR, Chang HL, Chang HW, Huang CC, Wang HR, Hwang-Verslues WW, Wu CH, Ho YS.
    Environ Toxicol; 2019 Jan 01; 34(1):73-82. PubMed ID: 30259641
    [Abstract] [Full Text] [Related]

  • 15. Agonist and antagonist effects of tobacco-related nitrosamines on human α4β2 nicotinic acetylcholine receptors.
    Brusco S, Ambrosi P, Meneghini S, Becchetti A.
    Front Pharmacol; 2015 Jan 01; 6():201. PubMed ID: 26441658
    [Abstract] [Full Text] [Related]

  • 16. SLURP-1 and -2 in normal, immortalized and malignant oral keratinocytes.
    Arredondo J, Chernyavsky AI, Grando SA.
    Life Sci; 2007 May 30; 80(24-25):2243-7. PubMed ID: 17280689
    [Abstract] [Full Text] [Related]

  • 17. A study of tobacco carcinogenesis, LIII: carcinogenicity of N'-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mink (Mustela vison).
    Koppang N, Rivenson A, Dahle HK, Hoffmann D.
    Cancer Lett; 1997 Jan 01; 111(1-2):167-71. PubMed ID: 9022142
    [Abstract] [Full Text] [Related]

  • 18. Stereoselective metabolism of nicotine and tobacco-specific N-nitrosamines to 4-hydroxy-4-(3-pyridyl)butanoic acid in rats.
    Trushin N, Hecht SS.
    Chem Res Toxicol; 1999 Feb 01; 12(2):164-71. PubMed ID: 10027794
    [Abstract] [Full Text] [Related]

  • 19. Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells.
    Tsurutani J, Castillo SS, Brognard J, Granville CA, Zhang C, Gills JJ, Sayyah J, Dennis PA.
    Carcinogenesis; 2005 Jul 01; 26(7):1182-95. PubMed ID: 15790591
    [Abstract] [Full Text] [Related]

  • 20. Formation of hemoglobin adducts upon treatment of F344 rats with the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine.
    Carmella SG, Hecht SS.
    Cancer Res; 1987 May 15; 47(10):2626-30. PubMed ID: 3567895
    [Abstract] [Full Text] [Related]

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