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218 related items for PubMed ID: 16837456

  • 1. PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation.
    Holinstat M, Voss B, Bilodeau ML, McLaughlin JN, Cleator J, Hamm HE.
    J Biol Chem; 2006 Sep 08; 281(36):26665-74. PubMed ID: 16837456
    [Abstract] [Full Text] [Related]

  • 2. Protease-activated receptor-induced Akt activation--regulation and possible function.
    Reséndiz JC, Kroll MH, Lassila R.
    J Thromb Haemost; 2007 Dec 08; 5(12):2484-93. PubMed ID: 17883592
    [Abstract] [Full Text] [Related]

  • 3. The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine.
    Grenegård M, Vretenbrant-Oberg K, Nylander M, Désilets S, Lindström EG, Larsson A, Ramström I, Ramström S, Lindahl TL.
    J Biol Chem; 2008 Jul 04; 283(27):18493-504. PubMed ID: 18480058
    [Abstract] [Full Text] [Related]

  • 4. Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling.
    Kim S, Foster C, Lecchi A, Quinton TM, Prosser DM, Jin J, Cattaneo M, Kunapuli SP.
    Blood; 2002 May 15; 99(10):3629-36. PubMed ID: 11986217
    [Abstract] [Full Text] [Related]

  • 5. Protease-activating receptor-4 induces full platelet spreading on a fibrinogen matrix: involvement of ERK2 and p38 and Ca2+ mobilization.
    Mazharian A, Roger S, Berrou E, Adam F, Kauskot A, Nurden P, Jandrot-Perrus M, Bryckaert M.
    J Biol Chem; 2007 Feb 23; 282(8):5478-87. PubMed ID: 17200114
    [Abstract] [Full Text] [Related]

  • 6. The roles and mechanisms of PAR4 and P2Y12/phosphatidylinositol 3-kinase pathway in maintaining thrombin-induced platelet aggregation.
    Wu CC, Wu SY, Liao CY, Teng CM, Wu YC, Kuo SC.
    Br J Pharmacol; 2010 Oct 23; 161(3):643-58. PubMed ID: 20880402
    [Abstract] [Full Text] [Related]

  • 7. Protease-activated receptor-4 (PAR4) variant influences on platelet reactivity induced by PAR4-activating peptide through altered Ca2+ mobilization and ERK phosphorylation in healthy Japanese subjects.
    Morikawa Y, Kato H, Kashiwagi H, Nishiura N, Akuta K, Honda S, Kanakura Y, Tomiyama Y.
    Thromb Res; 2018 Feb 23; 162():44-52. PubMed ID: 29289806
    [Abstract] [Full Text] [Related]

  • 8. Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets.
    Covic L, Gresser AL, Kuliopulos A.
    Biochemistry; 2000 May 09; 39(18):5458-67. PubMed ID: 10820018
    [Abstract] [Full Text] [Related]

  • 9. The protease-activated receptor 4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor 4 desensitization, and is blocked by non-competitive P2Y12 inhibition.
    Whitley MJ, Henke DM, Ghazi A, Nieman M, Stoller M, Simon LM, Chen E, Vesci J, Holinstat M, McKenzie SE, Shaw CA, Edelstein LC, Bray PF.
    J Thromb Haemost; 2018 Dec 09; 16(12):2501-2514. PubMed ID: 30347494
    [Abstract] [Full Text] [Related]

  • 10. Antithrombotic effects of PAR1 and PAR4 antagonists evaluated under flow and static conditions.
    Hosokawa K, Ohnishi T, Miura N, Sameshima H, Koide T, Tanaka KA, Maruyama I.
    Thromb Res; 2014 Jan 09; 133(1):66-72. PubMed ID: 24268424
    [Abstract] [Full Text] [Related]

  • 11. PAR1 antagonists inhibit thrombin-induced platelet activation whilst leaving the PAR4-mediated response intact.
    Judge HM, Jennings LK, Moliterno DJ, Hord E, Ecob R, Tricoci P, Rorick T, Kotha J, Storey RF.
    Platelets; 2015 Jan 09; 26(3):236-42. PubMed ID: 24750101
    [Abstract] [Full Text] [Related]

  • 12. Thrombin-induced platelet PAR4 activation: role of glycoprotein Ib and ADP.
    Adam F, Verbeuren TJ, Fauchère JL, Guillin MC, Jandrot-Perrus M.
    J Thromb Haemost; 2003 Apr 09; 1(4):798-804. PubMed ID: 12871418
    [Abstract] [Full Text] [Related]

  • 13. Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway.
    Holinstat M, Voss B, Bilodeau ML, Hamm HE.
    Mol Pharmacol; 2007 Mar 09; 71(3):686-94. PubMed ID: 17151288
    [Abstract] [Full Text] [Related]

  • 14. Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis.
    Leger AJ, Jacques SL, Badar J, Kaneider NC, Derian CK, Andrade-Gordon P, Covic L, Kuliopulos A.
    Circulation; 2006 Mar 07; 113(9):1244-54. PubMed ID: 16505172
    [Abstract] [Full Text] [Related]

  • 15. Contributions of Protease-Activated Receptors PAR1 and PAR4 to Thrombin-Induced GPIIbIIIa Activation in Human Platelets.
    Duvernay MT, Temple KJ, Maeng JG, Blobaum AL, Stauffer SR, Lindsley CW, Hamm HE.
    Mol Pharmacol; 2017 Jan 07; 91(1):39-47. PubMed ID: 27784794
    [Abstract] [Full Text] [Related]

  • 16. Glycoprotein IIb/IIIa and P2Y12 receptor antagonists yield additive inhibition of platelet aggregation, granule secretion, soluble CD40L release and procoagulant responses.
    Judge HM, Buckland RJ, Holgate CE, Storey RF.
    Platelets; 2005 Nov 07; 16(7):398-407. PubMed ID: 16236601
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of protease-activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood.
    French SL, Arthur JF, Lee H, Nesbitt WS, Andrews RK, Gardiner EE, Hamilton JR.
    J Thromb Haemost; 2016 Aug 07; 14(8):1642-54. PubMed ID: 26878340
    [Abstract] [Full Text] [Related]

  • 18. Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis.
    Tourdot BE, Conaway S, Niisuke K, Edelstein LC, Bray PF, Holinstat M.
    Arterioscler Thromb Vasc Biol; 2014 Dec 07; 34(12):2644-50. PubMed ID: 25278289
    [Abstract] [Full Text] [Related]

  • 19. [Role of adenosine diphosphate in the course of thrombin signal transmission].
    Han Y, Lu XX, Wang ZY, Dai L, Shen WH, Wu DP, Ruan CG.
    Zhonghua Yi Xue Za Zhi; 2006 Dec 12; 86(46):3299-301. PubMed ID: 17313817
    [Abstract] [Full Text] [Related]

  • 20. Q94 is not a selective modulator of proteinase-activated receptor 1 (PAR1) in platelets.
    Francis LRA, Millington-Burgess SL, Rahman T, Harper MT.
    Platelets; 2022 Oct 03; 33(7):1090-1095. PubMed ID: 35417662
    [Abstract] [Full Text] [Related]

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