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Journal Abstract Search

57 related items for PubMed ID: 16847427

  • 1. Identification of potential pharmacological and toxicological targets differentiating structural analogs by a combination of transcriptional profiling and promoter analysis in LS-180 and Caco-2 adenocarcinoma cell lines.
    Hartley DP, Dai X, Yabut J, Chu X, Cheng O, Zhang T, He YD, Roberts C, Ulrich R, Evers R, Evans DC.
    Pharmacogenet Genomics; 2006 Aug; 16(8):579-99. PubMed ID: 16847427
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  • 2. Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression.
    Hartley DP, Dai X, He YD, Carlini EJ, Wang B, Huskey SE, Ulrich RG, Rushmore TH, Evers R, Evans DC.
    Mol Pharmacol; 2004 May; 65(5):1159-71. PubMed ID: 15102944
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  • 7. Identification of amino acids in rat pregnane X receptor that determine species-specific activation.
    Tirona RG, Leake BF, Podust LM, Kim RB.
    Mol Pharmacol; 2004 Jan; 65(1):36-44. PubMed ID: 14722235
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  • 8. Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer.
    Gupta D, Venkatesh M, Wang H, Kim S, Sinz M, Goldberg GL, Whitney K, Longley C, Mani S.
    Clin Cancer Res; 2008 Sep 01; 14(17):5332-40. PubMed ID: 18765524
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  • 10. Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia.
    Lum PY, He YD, Slatter JG, Waring JF, Zelinsky N, Cavet G, Dai X, Fong O, Gum R, Jin L, Adamson GE, Roberts CJ, Olsen DB, Hazuda DJ, Ulrich RG.
    Genomics; 2007 Oct 01; 90(4):464-73. PubMed ID: 17719200
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  • 12. Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes.
    Dvorák Z, Maurel P, Vilarem MJ, Ulrichová J, Modrianský M.
    Cell Biol Toxicol; 2007 Mar 01; 23(2):63-73. PubMed ID: 16964586
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  • 15. Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes.
    Hariparsad N, Chu X, Yabut J, Labhart P, Hartley DP, Dai X, Evers R.
    Nucleic Acids Res; 2009 Mar 01; 37(4):1160-73. PubMed ID: 19129222
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  • 16. Involvement of ESE-3, epithelial-specific ETS factor family member 3, in transactivation of the ABCB1 gene via pregnane X receptor in intestine-derived LS180 cells but not in liver-derived HepG2 cells.
    Kameyama N, Kobayashi K, Shimizu S, Yamasaki Y, Endo M, Hashimoto M, Furihata T, Chiba K.
    Drug Metab Pharmacokinet; 2016 Oct 01; 31(5):340-348. PubMed ID: 27567379
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  • 17. Down-regulation of pregnane X receptor contributes to cell growth inhibition and apoptosis by anticancer agents in endometrial cancer cells.
    Masuyama H, Nakatsukasa H, Takamoto N, Hiramatsu Y.
    Mol Pharmacol; 2007 Oct 01; 72(4):1045-53. PubMed ID: 17636047
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  • 18. Development of in silico filters to predict activation of the pregnane X receptor (PXR) by structurally diverse drug-like molecules.
    Matter H, Anger LT, Giegerich C, Güssregen S, Hessler G, Baringhaus KH.
    Bioorg Med Chem; 2012 Sep 15; 20(18):5352-65. PubMed ID: 22560839
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