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Journal Abstract Search

952 related items for PubMed ID: 16855053

  • 1. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC, Wallace AD, Hodgson E, Rose RL.
    Drug Metab Dispos; 2006 Oct; 34(10):1779-85. PubMed ID: 16855053
    [Abstract] [Full Text] [Related]

  • 2. Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms.
    Lee HK, Moon JK, Chang CH, Choi H, Park HW, Park BS, Lee HS, Hwang EC, Lee YD, Liu KH, Kim JH.
    Drug Metab Dispos; 2006 Jul; 34(7):1090-5. PubMed ID: 16581944
    [Abstract] [Full Text] [Related]

  • 3. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H, White RB, Stevens JC.
    Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
    [Abstract] [Full Text] [Related]

  • 4. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
    Ramírez J, Innocenti F, Schuetz EG, Flockhart DA, Relling MV, Santucci R, Ratain MJ.
    Drug Metab Dispos; 2004 Sep; 32(9):930-6. PubMed ID: 15319333
    [Abstract] [Full Text] [Related]

  • 5. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.
    Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, Ikeda T, Kurihara A.
    Drug Metab Dispos; 2010 Jan; 38(1):92-9. PubMed ID: 19812348
    [Abstract] [Full Text] [Related]

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  • 7. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [Abstract] [Full Text] [Related]

  • 8. Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
    Hamaoka N, Oda Y, Hase I, Asada A.
    Br J Anaesth; 2001 Apr; 86(4):540-4. PubMed ID: 11573629
    [Abstract] [Full Text] [Related]

  • 9. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A, Satoh H, Thomas PE, Bush E, Moore D.
    Drug Metab Dispos; 1996 Sep; 24(9):940-7. PubMed ID: 8886602
    [Abstract] [Full Text] [Related]

  • 10. Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450.
    Rehmel JL, Eckstein JA, Farid NA, Heim JB, Kasper SC, Kurihara A, Wrighton SA, Ring BJ.
    Drug Metab Dispos; 2006 Apr; 34(4):600-7. PubMed ID: 16415119
    [Abstract] [Full Text] [Related]

  • 11. Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes.
    Zhang WV, D'Esposito F, Edwards RJ, Ramzan I, Murray M.
    Drug Metab Dispos; 2008 Dec; 36(12):2547-55. PubMed ID: 18809730
    [Abstract] [Full Text] [Related]

  • 12. Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.
    Jacobson PA, Green K, Birnbaum A, Remmel RP.
    Cancer Chemother Pharmacol; 2002 Jun; 49(6):461-7. PubMed ID: 12107550
    [Abstract] [Full Text] [Related]

  • 13. Stereo-selective metabolism of methadone by human liver microsomes and cDNA-expressed cytochrome P450s: a reconciliation.
    Chang Y, Fang WB, Lin SN, Moody DE.
    Basic Clin Pharmacol Toxicol; 2011 Jan; 108(1):55-62. PubMed ID: 20825389
    [Abstract] [Full Text] [Related]

  • 14. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
    Lalovic B, Phillips B, Risler LL, Howald W, Shen DD.
    Drug Metab Dispos; 2004 Apr; 32(4):447-54. PubMed ID: 15039299
    [Abstract] [Full Text] [Related]

  • 15. Involvement of CYP2B6 in n-demethylation of ketamine in human liver microsomes.
    Yanagihara Y, Kariya S, Ohtani M, Uchino K, Aoyama T, Yamamura Y, Iga T.
    Drug Metab Dispos; 2001 Jun; 29(6):887-90. PubMed ID: 11353758
    [Abstract] [Full Text] [Related]

  • 16. Examination of purported probes of human CYP2B6.
    Ekins S, VandenBranden M, Ring BJ, Wrighton SA.
    Pharmacogenetics; 1997 Jun; 7(3):165-79. PubMed ID: 9241656
    [Abstract] [Full Text] [Related]

  • 17. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.
    Hyland R, Roe EG, Jones BC, Smith DA.
    Br J Clin Pharmacol; 2001 Mar; 51(3):239-48. PubMed ID: 11298070
    [Abstract] [Full Text] [Related]

  • 18. Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.
    Faucette SR, Hawke RL, Lecluyse EL, Shord SS, Yan B, Laethem RM, Lindley CM.
    Drug Metab Dispos; 2000 Oct; 28(10):1222-30. PubMed ID: 10997944
    [Abstract] [Full Text] [Related]

  • 19. Investigation of the major human hepatic cytochrome P450 involved in 4-hydroxylation and N-dechloroethylation of trofosfamide.
    May-Manke A, Kroemer H, Hempel G, Bohnenstengel F, Hohenlöchter B, Blaschke G, Boos J.
    Cancer Chemother Pharmacol; 1999 Oct; 44(4):327-34. PubMed ID: 10447581
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of levo-alpha-Acetylmethadol (LAAM) by human liver cytochrome P450: involvement of CYP3A4 characterized by atypical kinetics with two binding sites.
    Oda Y, Kharasch ED.
    J Pharmacol Exp Ther; 2001 Apr; 297(1):410-22. PubMed ID: 11259570
    [Abstract] [Full Text] [Related]

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