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Journal Abstract Search

327 related items for PubMed ID: 16861921

  • 1. Targeting the PAS-A domain of HIF-1alpha for development of small molecule inhibitors of HIF-1.
    Park EJ, Kong D, Fisher R, Cardellina J, Shoemaker RH, Melillo G.
    Cell Cycle; 2006 Aug; 5(16):1847-53. PubMed ID: 16861921
    [Abstract] [Full Text] [Related]

  • 2. Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B.
    Partch CL, Gardner KH.
    Proc Natl Acad Sci U S A; 2011 May 10; 108(19):7739-44. PubMed ID: 21512126
    [Abstract] [Full Text] [Related]

  • 3. The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells.
    Wood SM, Gleadle JM, Pugh CW, Hankinson O, Ratcliffe PJ.
    J Biol Chem; 1996 Jun 21; 271(25):15117-23. PubMed ID: 8662957
    [Abstract] [Full Text] [Related]

  • 4. Cloning, characterization, hypoxia and heat shock response of hypoxia inducible factor-1 (HIF-1) from the small abalone Haliotis diversicolor.
    Cai X, Huang Y, Zhang X, Wang S, Zou Z, Wang G, Wang Y, Zhang Z.
    Gene; 2014 Jan 25; 534(2):256-64. PubMed ID: 24211325
    [Abstract] [Full Text] [Related]

  • 5. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity.
    Kong D, Park EJ, Stephen AG, Calvani M, Cardellina JH, Monks A, Fisher RJ, Shoemaker RH, Melillo G.
    Cancer Res; 2005 Oct 01; 65(19):9047-55. PubMed ID: 16204079
    [Abstract] [Full Text] [Related]

  • 6. Structural integration in hypoxia-inducible factors.
    Wu D, Potluri N, Lu J, Kim Y, Rastinejad F.
    Nature; 2015 Aug 20; 524(7565):303-8. PubMed ID: 26245371
    [Abstract] [Full Text] [Related]

  • 7. Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor.
    Yang J, Zhang L, Erbel PJ, Gardner KH, Ding K, Garcia JA, Bruick RK.
    J Biol Chem; 2005 Oct 28; 280(43):36047-54. PubMed ID: 16129688
    [Abstract] [Full Text] [Related]

  • 8. NcoA2-Dependent Inhibition of HIF-1α Activation Is Regulated via AhR.
    Tsai CH, Li CH, Liao PL, Cheng YW, Lin CH, Huang SH, Kang JJ.
    Toxicol Sci; 2015 Dec 28; 148(2):517-30. PubMed ID: 26350169
    [Abstract] [Full Text] [Related]

  • 9. MgcRacGAP, a cytoskeleton regulator, inhibits HIF-1 transcriptional activity by blocking its dimerization.
    Lyberopoulou A, Mylonis I, Papachristos G, Sagris D, Kalousi A, Befani C, Liakos P, Simos G, Georgatsou E.
    Biochim Biophys Acta; 2013 Jun 28; 1833(6):1378-87. PubMed ID: 23458834
    [Abstract] [Full Text] [Related]

  • 10. Hypoxia-inducible factors Per/ARNT/Sim domains: structure and function.
    Scheuermann TH, Yang J, Zhang L, Gardner KH, Bruick RK.
    Methods Enzymol; 2007 Jun 28; 435():3-24. PubMed ID: 17998046
    [Abstract] [Full Text] [Related]

  • 11. A HIF-1α-driven feed-forward loop augments HIF signalling in Hep3B cells by upregulation of ARNT.
    Mandl M, Lieberum MK, Depping R.
    Cell Death Dis; 2016 Jun 30; 7(6):e2284. PubMed ID: 27362802
    [Abstract] [Full Text] [Related]

  • 12. Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor.
    Kallio PJ, Pongratz I, Gradin K, McGuire J, Poellinger L.
    Proc Natl Acad Sci U S A; 1997 May 27; 94(11):5667-72. PubMed ID: 9159130
    [Abstract] [Full Text] [Related]

  • 13. Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.
    Gradin K, McGuire J, Wenger RH, Kvietikova I, fhitelaw ML, Toftgård R, Tora L, Gassmann M, Poellinger L.
    Mol Cell Biol; 1996 Oct 27; 16(10):5221-31. PubMed ID: 8816435
    [Abstract] [Full Text] [Related]

  • 14. Molecular characteristics and induction profiles of hypoxia-inducible factor-1α and other basic helix-loop-helix and Per-Arnt-Sim domain-containing proteins identified in a carcinogenic liver fluke Clonorchis sinensis.
    Kim SH, Oh GS, Sohn WM, Lee K, Yang HJ, Bae YA.
    Parasitology; 2019 Feb 27; 146(2):176-186. PubMed ID: 30070186
    [Abstract] [Full Text] [Related]

  • 15. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors.
    Chau NM, Rogers P, Aherne W, Carroll V, Collins I, McDonald E, Workman P, Ashcroft M.
    Cancer Res; 2005 Jun 01; 65(11):4918-28. PubMed ID: 15930314
    [Abstract] [Full Text] [Related]

  • 16. Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interaction.
    Cardoso R, Love R, Nilsson CL, Bergqvist S, Nowlin D, Yan J, Liu KK, Zhu J, Chen P, Deng YL, Dyson HJ, Greig MJ, Brooun A.
    Protein Sci; 2012 Dec 01; 21(12):1885-96. PubMed ID: 23033253
    [Abstract] [Full Text] [Related]

  • 17. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
    Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH, Melillo G.
    Cancer Res; 2002 Aug 01; 62(15):4316-24. PubMed ID: 12154035
    [Abstract] [Full Text] [Related]

  • 18. Cloning and characterization of hypoxia-inducible factor-1 subunits from Ascaris suum - a parasitic nematode highly adapted to changes of oxygen conditions during its life cycle.
    Goto M, Amino H, Nakajima M, Tsuji N, Sakamoto K, Kita K.
    Gene; 2013 Mar 01; 516(1):39-47. PubMed ID: 23268347
    [Abstract] [Full Text] [Related]

  • 19. The Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT/HIF-1β) is influenced by hypoxia and hypoxia-mimetics.
    Wolff M, Jelkmann W, Dunst J, Depping R.
    Cell Physiol Biochem; 2013 Mar 01; 32(4):849-58. PubMed ID: 24081025
    [Abstract] [Full Text] [Related]

  • 20. A cell-penetrating peptide suppresses the hypoxia inducible factor-1 function by binding to the helix-loop-helix domain of the aryl hydrocarbon receptor nuclear translocator.
    Wang Y, Thompson JD, Chan WK.
    Chem Biol Interact; 2013 Apr 25; 203(2):401-11. PubMed ID: 23454269
    [Abstract] [Full Text] [Related]

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