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Journal Abstract Search

132 related items for PubMed ID: 1686232

  • 21. Stereoselective first-pass metabolism of verapamil in the small intestine and liver in rats.
    Hanada K, Ikemi Y, Kukita K, Mihara K, Ogata H.
    Drug Metab Dispos; 2008 Oct; 36(10):2037-42. PubMed ID: 18617604
    [Abstract] [Full Text] [Related]

  • 22. Stereoselective metabolism of cisapride and enantiomer-enantiomer interaction in human cytochrome P450 enzymes: major role of CYP3A.
    Desta Z, Soukhova N, Morocho AM, Flockhart DA.
    J Pharmacol Exp Ther; 2001 Aug; 298(2):508-20. PubMed ID: 11454912
    [Abstract] [Full Text] [Related]

  • 23. Species differences in the toxicity and cytochrome P450 IIIA-dependent metabolism of digitoxin.
    Eberhart DC, Gemzik B, Halvorson MR, Parkinson A.
    Mol Pharmacol; 1991 Nov; 40(5):859-67. PubMed ID: 1944247
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  • 24. Characteristics of warfarin hydroxylation catalyzed by human liver microsomes.
    Rettie AE, Eddy AC, Heimark LD, Gibaldi M, Trager WF.
    Drug Metab Dispos; 1989 Nov; 17(3):265-70. PubMed ID: 2568906
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  • 25. Prediction of species differences (rats, dogs, humans) in the in vivo metabolic clearance of YM796 by the liver from in vitro data.
    Iwatsubo T, Suzuki H, Sugiyama Y.
    J Pharmacol Exp Ther; 1997 Nov; 283(2):462-9. PubMed ID: 9353358
    [Abstract] [Full Text] [Related]

  • 26. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS, Hatch HL, Kosea F, Nguyen HT, Choo EF, McClure KF, Taylor TJ, Henne KR, Kuperman AV, Dombroski MA, Letavic MA.
    Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
    [Abstract] [Full Text] [Related]

  • 27. In vivo pharmacokinetics of felodipine predicted from in vitro studies in rat, dog and man.
    Bäärnhielm C, Dahlbäck H, Skånberg I.
    Acta Pharmacol Toxicol (Copenh); 1986 Aug; 59(2):113-22. PubMed ID: 3776550
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  • 28. Stereoselectivity in the metabolism of disopyramide enantiomers in rat and dog.
    Cook CS, Karim A, Sollman P.
    Drug Metab Dispos; 1982 Aug; 10(2):116-21. PubMed ID: 6124395
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  • 29. In vitro hepatic metabolism of ABT-418 in chimpanzee (Pan troglodytes). A unique pattern of microsomal flavin-containing monooxygenase-dependent stereoselective N'-oxidation.
    Rodrigues AD, Kukulka MJ, Ferrero JL, Cashman JR.
    Drug Metab Dispos; 1995 Oct; 23(10):1143-52. PubMed ID: 8654204
    [Abstract] [Full Text] [Related]

  • 30. Oxidation of (R)- and (S)-propranolol in human and dog liver microsomes. Species differences in stereoselectivity.
    von Bahr C, Hermansson J, Lind M.
    J Pharmacol Exp Ther; 1982 Aug; 222(2):458-62. PubMed ID: 7097564
    [Abstract] [Full Text] [Related]

  • 31. Pharmacokinetics and metabolism of vinyl fluoride in vivo and in vitro.
    Cantoreggi S, Keller DA.
    Toxicol Appl Pharmacol; 1997 Mar; 143(1):130-9. PubMed ID: 9073601
    [Abstract] [Full Text] [Related]

  • 32. Sex difference in the stereoselective metabolism of a new dihydropyridine calcium channel blocker, in rat studies in vivo and in vitro.
    Takayama F, Saito K, Ishii Y, Shiratori K, Ohtawa M.
    Xenobiotica; 1991 May; 21(5):557-68. PubMed ID: 1949888
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  • 33. Oxidation of nilvadipine, a new dihydropyridine calcium antagonist, to the corresponding pyridine by rat liver microsomes.
    Niwa T, Tokuma Y, Noguchi H.
    Xenobiotica; 1988 Feb; 18(2):217-24. PubMed ID: 3376493
    [Abstract] [Full Text] [Related]

  • 34. Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes.
    Wienkers LC, Allievi C, Hauer MJ, Wynalda MA.
    Drug Metab Dispos; 1999 Nov; 27(11):1334-40. PubMed ID: 10534319
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  • 35. The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance.
    Vickers AE, Connors S, Zollinger M, Biggi WA, Larrauri A, Vogelaar JP, Brendel K.
    Drug Metab Dispos; 1993 Nov; 21(3):454-9. PubMed ID: 8100501
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  • 36. Metabolism of lovastatin by rat and human liver microsomes in vitro.
    Greenspan MD, Yudkovitz JB, Alberts AW, Argenbright LS, Arison BH, Smith JL.
    Drug Metab Dispos; 1988 Nov; 16(5):678-82. PubMed ID: 2906589
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  • 37. Biotransformation of tolterodine, a new muscarinic receptor antagonist, in mice, rats, and dogs.
    Andersson SH, Lindgren A, Postlind H.
    Drug Metab Dispos; 1998 Jun; 26(6):528-35. PubMed ID: 9616187
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  • 38. Enantioselective CE analysis of hepatic ketamine metabolism in different species in vitro.
    Schmitz A, Thormann W, Moessner L, Theurillat R, Helmja K, Mevissen M.
    Electrophoresis; 2010 May; 31(9):1506-16. PubMed ID: 20358543
    [Abstract] [Full Text] [Related]

  • 39. Stereoselective oxidation and plasma protein binding of nilvadipine, a new dihydropyridine calcium antagonist, in man.
    Niwa T, Tokuma Y, Nakagawa K, Noguchi H, Yamazoe Y, Kato R.
    Res Commun Chem Pathol Pharmacol; 1988 May; 60(2):161-72. PubMed ID: 3393731
    [Abstract] [Full Text] [Related]

  • 40. Species differences for stereoselective metabolism of ethofumesate and its enantiomers in vitro.
    Zhu W, Dang Z, Qiu J, Liu Y, Lv C, Diao J, Zhou Z.
    Xenobiotica; 2009 Sep; 39(9):649-55. PubMed ID: 19552529
    [Abstract] [Full Text] [Related]

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