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Journal Abstract Search


132 related items for PubMed ID: 1686246

  • 1. Metabolism of 3-methylindole in human tissues.
    Ruangyuttikarn W, Appleton ML, Yost GS.
    Drug Metab Dispos; 1991; 19(5):977-84. PubMed ID: 1686246
    [Abstract] [Full Text] [Related]

  • 2. Production and characterization of specific antibodies: utilization to predict organ- and species-selective pneumotoxicity of 3-methylindole.
    Kaster JK, Yost GS.
    Toxicol Appl Pharmacol; 1997 Apr; 143(2):324-37. PubMed ID: 9144449
    [Abstract] [Full Text] [Related]

  • 3. Glutathione adduct formation with microsomally activated metabolites of the pulmonary alkylating and cytotoxic agent, 3-methylindole.
    Nocerini MR, Carlson JR, Yost GS.
    Toxicol Appl Pharmacol; 1985 Oct; 81(1):75-84. PubMed ID: 4049423
    [Abstract] [Full Text] [Related]

  • 4. Adducts of 3-methylindole and glutathione: species differences in organ-selective bioactivation.
    Nocerini MR, Carlson JR, Yost GS.
    Toxicol Lett; 1985 Nov; 28(2-3):79-87. PubMed ID: 4071564
    [Abstract] [Full Text] [Related]

  • 5. Electrophilic metabolites of 3-methylindole as toxic intermediates in pulmonary oedema.
    Nocerini MR, Carlson JR, Yost GS.
    Xenobiotica; 1984 Jul; 14(7):561-4. PubMed ID: 6506769
    [Abstract] [Full Text] [Related]

  • 6. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ, Webb CD, Yao M, Weedon AC, Bend JR.
    Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258
    [Abstract] [Full Text] [Related]

  • 7. Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations.
    Madan A, Parkinson A.
    Drug Metab Dispos; 1996 Dec; 24(12):1307-13. PubMed ID: 8971135
    [Abstract] [Full Text] [Related]

  • 8. Cytochrome P-450-dependent bioactivation of 1,1-dichloroethylene to a reactive epoxide in human lung and liver microsomes.
    Dowsley TF, Reid K, Petsikas D, Ulreich JB, Fisher RL, Forkert PG.
    J Pharmacol Exp Ther; 1999 May; 289(2):641-8. PubMed ID: 10215634
    [Abstract] [Full Text] [Related]

  • 9. Metabolism and bioactivation of 3-methylindole by Clara cells, alveolar macrophages, and subcellular fractions from rabbit lungs.
    Thornton-Manning JR, Nichols WK, Manning BW, Skiles GL, Yost GS.
    Toxicol Appl Pharmacol; 1993 Oct; 122(2):182-90. PubMed ID: 8212000
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of 3-methylindole bioactivation by the cytochrome P-450 suicide substrates 1-aminobenzotriazole and alpha-methylbenzylaminobenzotriazole.
    Huijzer JC, Adams JD, Jaw JY, Yost GS.
    Drug Metab Dispos; 1989 Oct; 17(1):37-42. PubMed ID: 2566467
    [Abstract] [Full Text] [Related]

  • 11. Evidence for metabolism of 3-methylindole by prostaglandin H synthase and mixed-function oxidases in goat lung and liver microsomes.
    Formosa PJ, Bray TM.
    Biochem Pharmacol; 1988 Nov 15; 37(22):4359-66. PubMed ID: 3143368
    [Abstract] [Full Text] [Related]

  • 12. Metabolism and bioactivation of 3-methylindole by human liver microsomes.
    Yan Z, Easterwood LM, Maher N, Torres R, Huebert N, Yost GS.
    Chem Res Toxicol; 2007 Jan 15; 20(1):140-8. PubMed ID: 17226936
    [Abstract] [Full Text] [Related]

  • 13. In vitro covalent binding of 3-[14C]methylindole metabolites in goat tissues.
    Bray TM, Carlson JR, Nocerini MR.
    Proc Soc Exp Biol Med; 1984 May 15; 176(1):48-53. PubMed ID: 6709651
    [Abstract] [Full Text] [Related]

  • 14. The effect of 3-methylindole on superoxide and hydrogen peroxide production and NADPH oxidation by goat lung microsomes.
    Laegreid WW, Breeze RG.
    Res Commun Chem Pathol Pharmacol; 1985 Mar 15; 47(3):387-97. PubMed ID: 2986255
    [Abstract] [Full Text] [Related]

  • 15. Metabolism-dependent covalent binding of (S)-[5-3H]nicotine to liver and lung microsomal macromolecules.
    Shigenaga MK, Trevor AJ, Castagnoli N.
    Drug Metab Dispos; 1988 Mar 15; 16(3):397-402. PubMed ID: 2900731
    [Abstract] [Full Text] [Related]

  • 16. Hepatic and pulmonary microsomal metabolism of naphthalene to glutathione adducts: factors affecting the relative rates of conjugate formation.
    Buckpitt AR, Bahnson LS, Franklin RB.
    J Pharmacol Exp Ther; 1984 Nov 15; 231(2):291-300. PubMed ID: 6491983
    [Abstract] [Full Text] [Related]

  • 17. Identification of phase I metabolites of 3-methylindole produced by pig liver microsomes.
    Diaz GJ, Skordos KW, Yost GS, Squires EJ.
    Drug Metab Dispos; 1999 Oct 15; 27(10):1150-6. PubMed ID: 10497141
    [Abstract] [Full Text] [Related]

  • 18. Mechanistic studies on the cytochrome P450-catalyzed dehydrogenation of 3-methylindole.
    Skiles GL, Yost GS.
    Chem Res Toxicol; 1996 Oct 15; 9(1):291-7. PubMed ID: 8924606
    [Abstract] [Full Text] [Related]

  • 19. Comparative studies of the in vitro metabolism and covalent binding of 14C-benzene by liver slices and microsomal fraction of mouse, rat, and human.
    Brodfuehrer JI, Chapman DE, Wilke TJ, Powis G.
    Drug Metab Dispos; 1990 Oct 15; 18(1):20-7. PubMed ID: 1970773
    [Abstract] [Full Text] [Related]

  • 20. Cloning and expression of CYP2F3, a cytochrome P450 that bioactivates the selective pneumotoxins 3-methylindole and naphthalene.
    Wang H, Lanza DL, Yost GS.
    Arch Biochem Biophys; 1998 Jan 15; 349(2):329-40. PubMed ID: 9448722
    [Abstract] [Full Text] [Related]


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