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Journal Abstract Search

209 related items for PubMed ID: 16868077

  • 1. E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system.
    Flierman D, Coleman CS, Pickart CM, Rapoport TA, Chau V.
    Proc Natl Acad Sci U S A; 2006 Aug 01; 103(31):11589-94. PubMed ID: 16868077
    [Abstract] [Full Text] [Related]

  • 2. TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.
    van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA, Lehner PJ.
    Proc Natl Acad Sci U S A; 2014 Aug 05; 111(31):11425-30. PubMed ID: 25030448
    [Abstract] [Full Text] [Related]

  • 3. Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol.
    Shamu CE, Flierman D, Ploegh HL, Rapoport TA, Chau V.
    Mol Biol Cell; 2001 Aug 05; 12(8):2546-55. PubMed ID: 11514634
    [Abstract] [Full Text] [Related]

  • 4. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation.
    van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, Lebbink RJ.
    Nat Commun; 2014 May 08; 5():3832. PubMed ID: 24807418
    [Abstract] [Full Text] [Related]

  • 5. Identifying the ERAD ubiquitin E3 ligases for viral and cellular targeting of MHC class I.
    van den Boomen DJ, Lehner PJ.
    Mol Immunol; 2015 Dec 08; 68(2 Pt A):106-11. PubMed ID: 26210183
    [Abstract] [Full Text] [Related]

  • 6. Structure and function of ubiquitin conjugating enzyme E2-25K: the tail is a core-dependent activity element.
    Haldeman MT, Xia G, Kasperek EM, Pickart CM.
    Biochemistry; 1997 Aug 26; 36(34):10526-37. PubMed ID: 9265633
    [Abstract] [Full Text] [Related]

  • 7. A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate.
    Li W, Tu D, Brunger AT, Ye Y.
    Nature; 2007 Mar 15; 446(7133):333-7. PubMed ID: 17310145
    [Abstract] [Full Text] [Related]

  • 8. The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site.
    Chen B, Mariano J, Tsai YC, Chan AH, Cohen M, Weissman AM.
    Proc Natl Acad Sci U S A; 2006 Jan 10; 103(2):341-6. PubMed ID: 16407162
    [Abstract] [Full Text] [Related]

  • 9. Human cytomegalovirus-encoded US2 and US11 target unassembled MHC class I heavy chains for degradation.
    Barel MT, Hassink GC, van Voorden S, Wiertz EJ.
    Mol Immunol; 2006 Mar 10; 43(8):1258-66. PubMed ID: 16098592
    [Abstract] [Full Text] [Related]

  • 10. Ubiquitination of MHC class I heavy chains is essential for dislocation by human cytomegalovirus-encoded US2 but not US11.
    Hassink GC, Barel MT, Van Voorden SB, Kikkert M, Wiertz EJ.
    J Biol Chem; 2006 Oct 06; 281(40):30063-71. PubMed ID: 16877758
    [Abstract] [Full Text] [Related]

  • 11. The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate.
    Shamu CE, Story CM, Rapoport TA, Ploegh HL.
    J Cell Biol; 1999 Oct 04; 147(1):45-58. PubMed ID: 10508854
    [Abstract] [Full Text] [Related]

  • 12. Ubiquitination is essential for human cytomegalovirus US11-mediated dislocation of MHC class I molecules from the endoplasmic reticulum to the cytosol.
    Kikkert M, Hassink G, Barel M, Hirsch C, van der Wal FJ, Wiertz E.
    Biochem J; 2001 Sep 01; 358(Pt 2):369-77. PubMed ID: 11513735
    [Abstract] [Full Text] [Related]

  • 13. Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum.
    Furman MH, Loureiro J, Ploegh HL, Tortorella D.
    J Biol Chem; 2003 Sep 12; 278(37):34804-11. PubMed ID: 12832421
    [Abstract] [Full Text] [Related]

  • 14. TRAM1 participates in human cytomegalovirus US2- and US11-mediated dislocation of an endoplasmic reticulum membrane glycoprotein.
    Oresic K, Ng CL, Tortorella D.
    J Biol Chem; 2009 Feb 27; 284(9):5905-14. PubMed ID: 19121997
    [Abstract] [Full Text] [Related]

  • 15. Dislocation of an endoplasmic reticulum membrane glycoprotein involves the formation of partially dislocated ubiquitinated polypeptides.
    Baker BM, Tortorella D.
    J Biol Chem; 2007 Sep 14; 282(37):26845-26856. PubMed ID: 17650499
    [Abstract] [Full Text] [Related]

  • 16. Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein.
    Fiebiger E, Story C, Ploegh HL, Tortorella D.
    EMBO J; 2002 Mar 01; 21(5):1041-53. PubMed ID: 11867532
    [Abstract] [Full Text] [Related]

  • 17. Multiple E2 ubiquitin-conjugating enzymes regulate human cytomegalovirus US2-mediated immunoreceptor downregulation.
    van de Weijer ML, Schuren ABC, van den Boomen DJH, Mulder A, Claas FHJ, Lehner PJ, Lebbink RJ, Wiertz EJHJ.
    J Cell Sci; 2017 Sep 01; 130(17):2883-2892. PubMed ID: 28743740
    [Abstract] [Full Text] [Related]

  • 18. Forced interaction of cell surface proteins with Derlin-1 in the endoplasmic reticulum is sufficient to induce their dislocation into the cytosol for degradation.
    Cho S, Lee M, Jun Y.
    Biochem Biophys Res Commun; 2013 Jan 11; 430(2):787-92. PubMed ID: 23206703
    [Abstract] [Full Text] [Related]

  • 19. MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation.
    Burr ML, van den Boomen DJ, Bye H, Antrobus R, Wiertz EJ, Lehner PJ.
    Proc Natl Acad Sci U S A; 2013 Aug 27; 110(35):14290-5. PubMed ID: 23929775
    [Abstract] [Full Text] [Related]

  • 20. The HCMV gene products US2 and US11 target MHC class I molecules for degradation in the cytosol.
    van der Wal FJ, Kikkert M, Wiertz E.
    Curr Top Microbiol Immunol; 2002 Aug 27; 269():37-55. PubMed ID: 12224515
    [Abstract] [Full Text] [Related]

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