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162 related items for PubMed ID: 16869740

  • 1. Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors.
    Thomas RK, Greulich H, Yuza Y, Lee JC, Tengs T, Feng W, Chen TH, Nickerson E, Simons J, Egholm M, Rothberg JM, Sellers WR, Meyerson ML.
    Cold Spring Harb Symp Quant Biol; 2005; 70():73-81. PubMed ID: 16869740
    [Abstract] [Full Text] [Related]

  • 2. Effect of epidermal growth factor receptor tyrosine kinase domain mutations on the outcome of patients with non-small cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.
    Jänne PA, Johnson BE.
    Clin Cancer Res; 2006 Jul 15; 12(14 Pt 2):4416s-4420s. PubMed ID: 16857820
    [Abstract] [Full Text] [Related]

  • 3. Resistance to an irreversible epidermal growth factor receptor (EGFR) inhibitor in EGFR-mutant lung cancer reveals novel treatment strategies.
    Yu Z, Boggon TJ, Kobayashi S, Jin C, Ma PC, Dowlati A, Kern JA, Tenen DG, Halmos B.
    Cancer Res; 2007 Nov 01; 67(21):10417-27. PubMed ID: 17974985
    [Abstract] [Full Text] [Related]

  • 4. Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors.
    Balak MN, Gong Y, Riely GJ, Somwar R, Li AR, Zakowski MF, Chiang A, Yang G, Ouerfelli O, Kris MG, Ladanyi M, Miller VA, Pao W.
    Clin Cancer Res; 2006 Nov 01; 12(21):6494-501. PubMed ID: 17085664
    [Abstract] [Full Text] [Related]

  • 5. EGFR inhibitors: what have we learned from the treatment of lung cancer?
    Giaccone G, Rodriguez JA.
    Nat Clin Pract Oncol; 2005 Nov 01; 2(11):554-61. PubMed ID: 16270096
    [Abstract] [Full Text] [Related]

  • 6. EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients.
    Tang X, Shigematsu H, Bekele BN, Roth JA, Minna JD, Hong WK, Gazdar AF, Wistuba II.
    Cancer Res; 2005 Sep 01; 65(17):7568-72. PubMed ID: 16140919
    [Abstract] [Full Text] [Related]

  • 7. Searching for a magic bullet in NSCLC: the role of epidermal growth factor receptor mutations and tyrosine kinase inhibitors.
    Wong KK.
    Lung Cancer; 2008 Jun 01; 60 Suppl 2():S10-8. PubMed ID: 18513579
    [Abstract] [Full Text] [Related]

  • 8. Impact of EGFR mutation analysis in non-small cell lung cancer.
    Yamamoto H, Toyooka S, Mitsudomi T.
    Lung Cancer; 2009 Mar 01; 63(3):315-21. PubMed ID: 18760859
    [Abstract] [Full Text] [Related]

  • 9. Cytomorphological correlates of epidermal growth factor receptor mutations in lung carcinoma.
    Brachtel EF, Iafrate AJ, Mark EJ, Deshpande V.
    Diagn Cytopathol; 2007 May 01; 35(5):257-62. PubMed ID: 17427221
    [Abstract] [Full Text] [Related]

  • 10. Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications.
    Wu CC, Hsu HY, Liu HP, Chang JW, Chen YT, Hsieh WY, Hsieh JJ, Hsieh MS, Chen YR, Huang SF.
    Cancer; 2008 Dec 01; 113(11):3199-208. PubMed ID: 18932251
    [Abstract] [Full Text] [Related]

  • 11. Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients.
    Yung TK, Chan KC, Mok TS, Tong J, To KF, Lo YM.
    Clin Cancer Res; 2009 Mar 15; 15(6):2076-84. PubMed ID: 19276259
    [Abstract] [Full Text] [Related]

  • 12. A new mechanism for primary resistance to gefitinib in lung adenocarcinoma: the role of a novel G796A mutation in exon 20 of EGFR.
    Uramoto H, Uchiumi T, Izumi H, Kohno K, Oyama T, Sugio K, Yasumoto K.
    Anticancer Res; 2007 Mar 15; 27(4B):2297-303. PubMed ID: 17695517
    [Abstract] [Full Text] [Related]

  • 13. EGFR mutations and the terminal respiratory unit.
    Yatabe Y.
    Cancer Metastasis Rev; 2010 Mar 15; 29(1):23-36. PubMed ID: 20135199
    [Abstract] [Full Text] [Related]

  • 14. Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.
    Bell DW, Gore I, Okimoto RA, Godin-Heymann N, Sordella R, Mulloy R, Sharma SV, Brannigan BW, Mohapatra G, Settleman J, Haber DA.
    Nat Genet; 2005 Dec 15; 37(12):1315-6. PubMed ID: 16258541
    [Abstract] [Full Text] [Related]

  • 15. Clustered genomic alterations in chromosome 7p dictate outcomes and targeted treatment responses of lung adenocarcinoma with EGFR-activating mutations.
    Yuan S, Yu SL, Chen HY, Hsu YC, Su KY, Chen HW, Chen CY, Yu CJ, Shih JY, Chang YL, Cheng CL, Hsu CP, Hsia JY, Lin CY, Wu G, Liu CH, Wang CD, Yang KC, Chen YW, Lai YL, Hsu CC, Lin TC, Yang TY, Chen KC, Hsu KH, Chen JJ, Chang GC, Li KC, Yang PC.
    J Clin Oncol; 2011 Sep 01; 29(25):3435-42. PubMed ID: 21810691
    [Abstract] [Full Text] [Related]

  • 16. Functional analysis of epidermal growth factor receptor (EGFR) mutations and potential implications for EGFR targeted therapy.
    Kancha RK, von Bubnoff N, Peschel C, Duyster J.
    Clin Cancer Res; 2009 Jan 15; 15(2):460-7. PubMed ID: 19147750
    [Abstract] [Full Text] [Related]

  • 17. EGFR FISH versus mutation: different tests, different end-points.
    Cappuzzo F.
    Lung Cancer; 2008 May 15; 60(2):160-5. PubMed ID: 18367287
    [Abstract] [Full Text] [Related]

  • 18. Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor.
    Alvarez JV, Greulich H, Sellers WR, Meyerson M, Frank DA.
    Cancer Res; 2006 Mar 15; 66(6):3162-8. PubMed ID: 16540667
    [Abstract] [Full Text] [Related]

  • 19. Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors.
    John T, Liu G, Tsao MS.
    Oncogene; 2009 Aug 15; 28 Suppl 1():S14-23. PubMed ID: 19680292
    [Abstract] [Full Text] [Related]

  • 20. Relationship of EGFR mutations, expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the NCI60 cell lines.
    Liu W, Wu X, Zhang W, Montenegro RC, Fackenthal DL, Spitz JA, Huff LM, Innocenti F, Das S, Cook EH, Cox NJ, Bates SE, Ratain MJ.
    Clin Cancer Res; 2007 Nov 15; 13(22 Pt 1):6788-95. PubMed ID: 18006781
    [Abstract] [Full Text] [Related]

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