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211 related items for PubMed ID: 16873540

  • 1. Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/db mice.
    Liu Y, Yan C, Wang Y, Nakagawa Y, Nerio N, Anghel A, Lutfy K, Friedman TC.
    Endocrinology; 2006 Nov; 147(11):5061-8. PubMed ID: 16873540
    [Abstract] [Full Text] [Related]

  • 2. Increased glucocorticoid receptor and 11{beta}-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice.
    Liu Y, Nakagawa Y, Wang Y, Sakurai R, Tripathi PV, Lutfy K, Friedman TC.
    Diabetes; 2005 Jan; 54(1):32-40. PubMed ID: 15616008
    [Abstract] [Full Text] [Related]

  • 3. Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.
    Cao G, Liang Y, Broderick CL, Oldham BA, Beyer TP, Schmidt RJ, Zhang Y, Stayrook KR, Suen C, Otto KA, Miller AR, Dai J, Foxworthy P, Gao H, Ryan TP, Jiang XC, Burris TP, Eacho PI, Etgen GJ.
    J Biol Chem; 2003 Jan 10; 278(2):1131-6. PubMed ID: 12414791
    [Abstract] [Full Text] [Related]

  • 4. Fenofibrate ameliorates diabetic and dyslipidemic profiles in KKAy mice partly via down-regulation of 11beta-HSD1, PEPCK and DGAT2. Comparison of PPARalpha, PPARgamma, and liver x receptor agonists.
    Srivastava RA.
    Eur J Pharmacol; 2009 Apr 01; 607(1-3):258-63. PubMed ID: 19245804
    [Abstract] [Full Text] [Related]

  • 5. Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.
    Liu Y, Nakagawa Y, Wang Y, Liu L, Du H, Wang W, Ren X, Lutfy K, Friedman TC.
    J Mol Endocrinol; 2008 Aug 01; 41(2):53-64. PubMed ID: 18524870
    [Abstract] [Full Text] [Related]

  • 6. Activation of the Liver X Receptor by Agonist TO901317 Improves Hepatic Insulin Resistance via Suppressing Reactive Oxygen Species and JNK Pathway.
    Dong Y, Gao G, Fan H, Li S, Li X, Liu W.
    PLoS One; 2015 Aug 01; 10(4):e0124778. PubMed ID: 25909991
    [Abstract] [Full Text] [Related]

  • 7. Sodium meta-arsenite ameliorates hyperglycemia in obese diabetic db/db mice by inhibition of hepatic gluconeogenesis.
    Lee YS, Lee EK, Oh HH, Choi CS, Kim S, Jun HS.
    J Diabetes Res; 2014 Aug 01; 2014():961732. PubMed ID: 25610880
    [Abstract] [Full Text] [Related]

  • 8. A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced C-reactive protein gene expression by liver X receptor.
    Blaschke F, Takata Y, Caglayan E, Collins A, Tontonoz P, Hsueh WA, Tangirala RK.
    Circ Res; 2006 Dec 08; 99(12):e88-99. PubMed ID: 17110595
    [Abstract] [Full Text] [Related]

  • 9. Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.
    Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J, Ishibashi S, Yamada N.
    Mol Endocrinol; 2003 Jul 08; 17(7):1255-67. PubMed ID: 12730332
    [Abstract] [Full Text] [Related]

  • 10. [Activation of liver X receptor regulates fatty acid synthase expression in diabetic liver].
    Wang B, Cheng LJ, Gao ZN, Zhang XY, Huo M, Zhang DJ, Wu J, Wei MF.
    Zhonghua Yi Xue Za Zhi; 2008 Mar 25; 88(12):848-52. PubMed ID: 18756992
    [Abstract] [Full Text] [Related]

  • 11. The effect of T0901317 on ATP-binding cassette transporter A1 and Niemann-Pick type C1 in apoE-/- mice.
    Dai XY, Ou X, Hao XR, Cao DL, Tang YL, Hu YW, Li XX, Tang CK.
    J Cardiovasc Pharmacol; 2008 May 25; 51(5):467-75. PubMed ID: 18437096
    [Abstract] [Full Text] [Related]

  • 12. Regulation of bile acid, cholesterol, and fatty acid synthesis in chicken primary hepatocytes by different concentrations of T0901317, an agonist of liver X receptors.
    Sato K, Kamada T.
    Comp Biochem Physiol A Mol Integr Physiol; 2011 Feb 25; 158(2):201-6. PubMed ID: 21056113
    [Abstract] [Full Text] [Related]

  • 13. Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity.
    Xu J, Wagoner G, Douglas JC, Drew PD.
    J Leukoc Biol; 2009 Aug 25; 86(2):401-9. PubMed ID: 19406833
    [Abstract] [Full Text] [Related]

  • 14. Liver X receptor agonist downregulates hepatic apoM expression in vivo and in vitro.
    Zhang X, Zhu Z, Luo G, Zheng L, Nilsson-Ehle P, Xu N.
    Biochem Biophys Res Commun; 2008 Jun 20; 371(1):114-7. PubMed ID: 18413148
    [Abstract] [Full Text] [Related]

  • 15. Liver X receptor agonist T0901317 reduces atherosclerotic lesions in apoE-/- mice by up-regulating NPC1 expression.
    Ou X, Dai X, Long Z, Tang Y, Cao D, Hao X, Hu Y, Li X, Tang C.
    Sci China C Life Sci; 2008 May 20; 51(5):418-29. PubMed ID: 18785587
    [Abstract] [Full Text] [Related]

  • 16. The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse.
    Chisholm JW, Hong J, Mills SA, Lawn RM.
    J Lipid Res; 2003 Nov 20; 44(11):2039-48. PubMed ID: 12923232
    [Abstract] [Full Text] [Related]

  • 17. LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins.
    Basciano H, Miller A, Baker C, Naples M, Adeli K.
    Am J Physiol Gastrointest Liver Physiol; 2009 Aug 20; 297(2):G323-32. PubMed ID: 19497957
    [Abstract] [Full Text] [Related]

  • 18. Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition.
    Renga B, Mencarelli A, D'Amore C, Cipriani S, Baldelli F, Zampella A, Distrutti E, Fiorucci S.
    FASEB J; 2012 Jul 20; 26(7):3021-31. PubMed ID: 22447981
    [Abstract] [Full Text] [Related]

  • 19. Liver X receptor activator downregulates angiotensin II type 1 receptor expression through dephosphorylation of Sp1.
    Imayama I, Ichiki T, Patton D, Inanaga K, Miyazaki R, Ohtsubo H, Tian Q, Yano K, Sunagawa K.
    Hypertension; 2008 Jun 20; 51(6):1631-6. PubMed ID: 18443233
    [Abstract] [Full Text] [Related]

  • 20. Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.
    Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N.
    Mol Endocrinol; 2003 Jul 20; 17(7):1240-54. PubMed ID: 12730331
    [Abstract] [Full Text] [Related]

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