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139 related items for PubMed ID: 16883550

  • 21. Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.
    Taub ME, Podila L, Ely D, Almeida I.
    Drug Metab Dispos; 2005 Nov; 33(11):1679-87. PubMed ID: 16093365
    [Abstract] [Full Text] [Related]

  • 22. Induction of multidrug resistance in MOLT-4 cells by anticancer agents is closely related to increased expression of functional P-glycoprotein and MDR1 mRNA.
    Liu ZL, Onda K, Tanaka S, Toma T, Hirano T, Oka K.
    Cancer Chemother Pharmacol; 2002 May; 49(5):391-7. PubMed ID: 11976833
    [Abstract] [Full Text] [Related]

  • 23. MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer.
    Fung KL, Pan J, Ohnuma S, Lund PE, Pixley JN, Kimchi-Sarfaty C, Ambudkar SV, Gottesman MM.
    Cancer Res; 2014 Jan 15; 74(2):598-608. PubMed ID: 24305879
    [Abstract] [Full Text] [Related]

  • 24. Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities.
    Morita N, Yasumori T, Nakayama K.
    Biochem Pharmacol; 2003 Jun 01; 65(11):1843-52. PubMed ID: 12781336
    [Abstract] [Full Text] [Related]

  • 25. A "silent" polymorphism in the MDR1 gene changes substrate specificity.
    Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, Gottesman MM.
    Science; 2007 Jan 26; 315(5811):525-8. PubMed ID: 17185560
    [Abstract] [Full Text] [Related]

  • 26. Risperidone and paliperidone inhibit p-glycoprotein activity in vitro.
    Zhu HJ, Wang JS, Markowitz JS, Donovan JL, Gibson BB, DeVane CL.
    Neuropsychopharmacology; 2007 Apr 26; 32(4):757-64. PubMed ID: 16936711
    [Abstract] [Full Text] [Related]

  • 27. Expression and functional activity of P-glycoprotein in passaged primary human nasal epithelial cell monolayers cultured by the air-liquid interface method for nasal drug transport study.
    Cho HJ, Choi MK, Lin H, Kim JS, Chung SJ, Shim CK, Kim DD.
    J Pharm Pharmacol; 2011 Mar 26; 63(3):385-91. PubMed ID: 21749386
    [Abstract] [Full Text] [Related]

  • 28. Inhibition of P-glycoprotein transport function and reversion of MDR1 multidrug resistance by cnidiadin.
    Barthomeuf C, Grassi J, Demeule M, Fournier C, Boivin D, Béliveau R.
    Cancer Chemother Pharmacol; 2005 Aug 26; 56(2):173-81. PubMed ID: 15824923
    [Abstract] [Full Text] [Related]

  • 29. Over-expression of MDR1 in amrubicinol-resistant lung cancer cells.
    Takakuwa O, Oguri T, Ozasa H, Uemura T, Kasai D, Miyazaki M, Maeno K, Sato S.
    Cancer Chemother Pharmacol; 2011 Sep 26; 68(3):669-76. PubMed ID: 21128075
    [Abstract] [Full Text] [Related]

  • 30. Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells.
    Troutman MD, Thakker DR.
    Pharm Res; 2003 Aug 26; 20(8):1192-9. PubMed ID: 12948017
    [Abstract] [Full Text] [Related]

  • 31. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine.
    Cvetkovic M, Leake B, Fromm MF, Wilkinson GR, Kim RB.
    Drug Metab Dispos; 1999 Aug 26; 27(8):866-71. PubMed ID: 10421612
    [Abstract] [Full Text] [Related]

  • 32. Different transport activity of human triallelic MDR1 893Ala/Ser/Thr variant and its association with herb extracts.
    Kim JH, Kim SR, Song IS, Shin HJ, Kim HS, Lee JH, Ko SG, Shin YC.
    Phytother Res; 2011 Aug 26; 25(8):1141-7. PubMed ID: 21287651
    [Abstract] [Full Text] [Related]

  • 33. Outward transfer of dopamine precursor L-3,4-dihydroxyphenylalanine (L-dopa) by native and human P-glycoprotein in LLC-PK(1) and LLC-GA5 col300 renal cells.
    Soares-Da-Silva P, Serrão MP.
    J Pharmacol Exp Ther; 2000 May 26; 293(2):697-704. PubMed ID: 10773046
    [Abstract] [Full Text] [Related]

  • 34. Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses.
    Kadioglu O, Saeed ME, Valoti M, Frosini M, Sgaragli G, Efferth T.
    Biochem Pharmacol; 2016 Mar 15; 104():42-51. PubMed ID: 26807479
    [Abstract] [Full Text] [Related]

  • 35. Effect of PCB-126 on intracellular accumulation and transepithelial transport of vinblastine in LLC-PK1 and its transformant cells expressing human P-glycoprotein.
    Sasawatari S, Toki M, Horie T, Nakano Y, Ikeda T, Ueda K, Fujise H.
    J Vet Med Sci; 2004 Sep 15; 66(9):1079-85. PubMed ID: 15472471
    [Abstract] [Full Text] [Related]

  • 36. Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models.
    Taur JS, Rodriguez-Proteau R.
    Xenobiotica; 2008 Dec 15; 38(12):1536-50. PubMed ID: 18951251
    [Abstract] [Full Text] [Related]

  • 37. Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
    Yasuda K, Lan LB, Sanglard D, Furuya K, Schuetz JD, Schuetz EG.
    J Pharmacol Exp Ther; 2002 Oct 15; 303(1):323-32. PubMed ID: 12235267
    [Abstract] [Full Text] [Related]

  • 38. HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.
    Lee CG, Gottesman MM, Cardarelli CO, Ramachandra M, Jeang KT, Ambudkar SV, Pastan I, Dey S.
    Biochemistry; 1998 Mar 17; 37(11):3594-601. PubMed ID: 9530286
    [Abstract] [Full Text] [Related]

  • 39. Inhibitors of mdr1-dependent transport activity delay accumulation of the mdr1 substrate rhodamine 123 in primary rat hepatocyte cultures.
    Hirsch-Ernst KI, Ziemann C, Rustenbeck I, Kahl GF.
    Toxicology; 2001 Oct 05; 167(1):47-57. PubMed ID: 11557129
    [Abstract] [Full Text] [Related]

  • 40. Effects of P-glycoprotein inhibitors on cadmium accumulation in cultured renal epithelial cells, LLC-PK1, and OK.
    Endo T, Kimura O, Sakata M.
    Toxicol Appl Pharmacol; 2002 Dec 15; 185(3):166-71. PubMed ID: 12498733
    [Abstract] [Full Text] [Related]

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