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1293 related items for PubMed ID: 16885195

  • 1. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME, Kabler SL, Fleming MH, Ravoori S, Gupta RC, Doehmer J, Morrow CS, Townsend AJ.
    Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195
    [Abstract] [Full Text] [Related]

  • 2. Protective efficacy of hGSTM1-1 against B[a]P and (+)- or (-)-B[a]P-7,8-dihydrodiol cytotoxicity, mutagenicity, and macromolecular adducts in V79 cells coexpressing hCYP1A1.
    Kushman ME, Kabler SL, Ahmad S, Doehmer J, Morrow CS, Townsend AJ.
    Toxicol Sci; 2007 Sep; 99(1):51-7. PubMed ID: 17525473
    [Abstract] [Full Text] [Related]

  • 3. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase.
    Hu X, Herzog C, Zimniak P, Singh SV.
    Cancer Res; 1999 May 15; 59(10):2358-62. PubMed ID: 10344744
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  • 4. Cytotoxicity and mutagenicity of 5-methylchrysene and its 1,2-dihydrodiol in V79MZ cells modified to express human CYP1A1 or CYP1B1, in the presence or absence of human GSTP1 coexpression.
    Ahmad S, Kabler SL, Rudd L, Amin S, Doehmer J, Morrow CS, Townsend AJ.
    Toxicol Lett; 2008 Dec 15; 183(1-3):99-104. PubMed ID: 18992797
    [Abstract] [Full Text] [Related]

  • 5. Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1.
    Kabler SL, Seidel A, Jacob J, Doehmer J, Morrow CS, Townsend AJ.
    Chem Biol Interact; 2009 May 15; 179(2-3):240-6. PubMed ID: 19330882
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  • 6. Overexpression of stably transfected human glutathione S-transferase P1-1 protects against DNA damage by benzo[a]pyrene diol-epoxide in human T47D cells.
    Fields WR, Morrow CS, Doss AJ, Sundberg K, Jernström B, Townsend AJ.
    Mol Pharmacol; 1998 Aug 15; 54(2):298-304. PubMed ID: 9687571
    [Abstract] [Full Text] [Related]

  • 7. Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells.
    Akerman GS, Rosenzweig BA, Domon OE, McGarrity LJ, Blankenship LR, Tsai CA, Culp SJ, MacGregor JT, Sistare FD, Chen JJ, Morris SM.
    Mutat Res; 2004 May 18; 549(1-2):43-64. PubMed ID: 15120962
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  • 8. Mutagenic response of the endogenous hprt gene and lacI transgene in benzo[a]pyrene-treated Big Blue B6C3F1 mice.
    Skopek TR, Kort KL, Marino DR, Mittal LV, Umbenhauer DR, Laws GM, Adams SP.
    Environ Mol Mutagen; 1996 May 18; 28(4):376-84. PubMed ID: 8991066
    [Abstract] [Full Text] [Related]

  • 9. Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (+/-)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1.
    Kushman ME, Kabler SL, Ahmad S, Doehmer J, Morrow CS, Townsend AJ.
    Mutat Res; 2007 Nov 01; 624(1-2):80-7. PubMed ID: 17509623
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  • 11. Interspecies differences in the major DNA adducts formed from benzo(a)pyrene but not 7,12-dimethylbenz(a)anthracene in rat and human mammary cell cultures.
    Moore CJ, Pruess-Schwartz D, Mauthe RJ, Gould MN, Baird WM.
    Cancer Res; 1987 Aug 15; 47(16):4402-6. PubMed ID: 3111685
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  • 13. Formation of lysine 63-linked poly-ubiquitin chains protects human lung cells against benzo[a]pyrene-diol-epoxide-induced mutagenicity.
    Langie SA, Knaapen AM, Ramaekers CH, Theys J, Brun J, Godschalk RW, van Schooten FJ, Lambin P, Gray DA, Wouters BG, Chiu RK.
    DNA Repair (Amst); 2007 Jun 01; 6(6):852-62. PubMed ID: 17395554
    [Abstract] [Full Text] [Related]

  • 14. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Hu X, O'Donnell R, Srivastava SK, Xia H, Zimniak P, Nanduri B, Bleicher RJ, Awasthi S, Awasthi YC, Ji X, Singh SV.
    Biochem Biophys Res Commun; 1997 Jun 18; 235(2):424-8. PubMed ID: 9199210
    [Abstract] [Full Text] [Related]

  • 15. Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-nitrobenzo[a]pyrene trans-7,8- diol-anti-9,10-epoxide.
    Zhan DJ, Heflich RH, Fu PP.
    Environ Mol Mutagen; 1996 Jun 18; 27(1):19-29. PubMed ID: 8625944
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  • 19. Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells.
    Chiang HC, Tsou TC.
    Toxicol In Vitro; 2009 Aug 18; 23(5):897-905. PubMed ID: 19470404
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  • 20. Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53.
    Hockley SL, Arlt VM, Jahnke G, Hartwig A, Giddings I, Phillips DH.
    Carcinogenesis; 2008 Jan 18; 29(1):202-10. PubMed ID: 17942461
    [Abstract] [Full Text] [Related]

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