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357 related items for PubMed ID: 16887103
1. Cytochrome P450 reductase dependent inhibition of cytochrome P450 2B1 activity: Implications for gene directed enzyme prodrug therapy. Lengler J, Omann M, Düvier D, Holzmüller H, Gregor W, Salmons B, Günzburg WH, Renner M. Biochem Pharmacol; 2006 Sep 28; 72(7):893-901. PubMed ID: 16887103 [Abstract] [Full Text] [Related]
2. Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene. Chen L, Waxman DJ, Chen D, Kufe DW. Cancer Res; 1996 Mar 15; 56(6):1331-40. PubMed ID: 8640822 [Abstract] [Full Text] [Related]
3. Potentiation of cytochrome P450/cyclophosphamide-based cancer gene therapy by coexpression of the P450 reductase gene. Chen L, Yu LJ, Waxman DJ. Cancer Res; 1997 Nov 01; 57(21):4830-7. PubMed ID: 9354446 [Abstract] [Full Text] [Related]
4. Necrotic, rather than apoptotic, cell death caused by cytochrome P450-activated ifosfamide. Karle P, Renner M, Salmons B, Günzburg WH. Cancer Gene Ther; 2001 Mar 01; 8(3):220-30. PubMed ID: 11332993 [Abstract] [Full Text] [Related]
5. Effects of hypoxia and limited diffusion in tumor cell microenvironment on bystander effect of P450 prodrug therapy. Günther M, Waxman DJ, Wagner E, Ogris M. Cancer Gene Ther; 2006 Aug 01; 13(8):771-9. PubMed ID: 16543915 [Abstract] [Full Text] [Related]
6. Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene therapy strategy. Chen L, Waxman DJ. Cancer Res; 1995 Feb 01; 55(3):581-9. PubMed ID: 7834628 [Abstract] [Full Text] [Related]
7. Activation of oxazaphosphorines by cytochrome P450: application to gene-directed enzyme prodrug therapy for cancer. Roy P, Waxman DJ. Toxicol In Vitro; 2006 Mar 01; 20(2):176-86. PubMed ID: 16293390 [Abstract] [Full Text] [Related]
8. Diffusible cytotoxic metabolites contribute to the in vitro bystander effect associated with the cyclophosphamide/cytochrome P450 2B1 cancer gene therapy paradigm. Wei MX, Tamiya T, Rhee RJ, Breakefield XO, Chiocca EA. Clin Cancer Res; 1995 Oct 01; 1(10):1171-7. PubMed ID: 9815909 [Abstract] [Full Text] [Related]
9. Enantioselective metabolism and cytotoxicity of R-ifosfamide and S-ifosfamide by tumor cell-expressed cytochromes P450. Chen CS, Jounaidi Y, Waxman DJ. Drug Metab Dispos; 2005 Sep 01; 33(9):1261-7. PubMed ID: 15919850 [Abstract] [Full Text] [Related]
10. Targeted chemotherapy by intratumour injection of encapsulated cells engineered to produce CYP2B1, an ifosfamide activating cytochrome P450. Löhr M, Müller P, Karle P, Stange J, Mitzner S, Jesnowski R, Nizze H, Nebe B, Liebe S, Salmons B, Günzburg WH. Gene Ther; 1998 Aug 01; 5(8):1070-8. PubMed ID: 10326030 [Abstract] [Full Text] [Related]
11. Peritoneal cancer treatment with CYP2B1 transfected, microencapsulated cells and ifosfamide. Samel S, Keese M, Lux A, Jesnowski R, Prosst R, Saller R, Hafner M, Sturm J, Post S, Löhr M. Cancer Gene Ther; 2006 Jan 01; 13(1):65-73. PubMed ID: 16096652 [Abstract] [Full Text] [Related]