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Journal Abstract Search

329 related items for PubMed ID: 16889837

  • 1. Allosteric agonists of 7TM receptors: expanding the pharmacological toolbox.
    Langmead CJ, Christopoulos A.
    Trends Pharmacol Sci; 2006 Sep; 27(9):475-81. PubMed ID: 16889837
    [Abstract] [Full Text] [Related]

  • 2. Orthosteric/allosteric bitopic ligands: going hybrid at GPCRs.
    Valant C, Sexton PM, Christopoulos A.
    Mol Interv; 2009 Jun; 9(3):125-35. PubMed ID: 19592673
    [Abstract] [Full Text] [Related]

  • 3. Ligand detection in the allosteric world.
    Kenakin TP.
    J Biomol Screen; 2010 Feb; 15(2):119-30. PubMed ID: 20086210
    [Abstract] [Full Text] [Related]

  • 4. Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors.
    Kenakin T.
    Trends Pharmacol Sci; 2007 Aug; 28(8):407-15. PubMed ID: 17629960
    [Abstract] [Full Text] [Related]

  • 5. Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives.
    Urwyler S.
    Pharmacol Rev; 2011 Mar; 63(1):59-126. PubMed ID: 21228259
    [Abstract] [Full Text] [Related]

  • 6. When simple agonism is not enough: emerging modalities of GPCR ligands.
    Smith NJ, Bennett KA, Milligan G.
    Mol Cell Endocrinol; 2011 Jan 15; 331(2):241-7. PubMed ID: 20654693
    [Abstract] [Full Text] [Related]

  • 7. G-protein-coupled receptor allosterism: the promise and the problem(s).
    Christopoulos A, May LT, Avlani VA, Sexton PM.
    Biochem Soc Trans; 2004 Nov 15; 32(Pt 5):873-7. PubMed ID: 15494038
    [Abstract] [Full Text] [Related]

  • 8. Allosteric properties of G protein-coupled receptor oligomers.
    Springael JY, Urizar E, Costagliola S, Vassart G, Parmentier M.
    Pharmacol Ther; 2007 Sep 15; 115(3):410-8. PubMed ID: 17655934
    [Abstract] [Full Text] [Related]

  • 9. Allosteric modulation of G-protein coupled receptors.
    Jensen AA, Spalding TA.
    Eur J Pharm Sci; 2004 Mar 15; 21(4):407-20. PubMed ID: 14998571
    [Abstract] [Full Text] [Related]

  • 10. Identifying novel modulators of G protein-coupled receptors via interaction at allosteric sites.
    Presland J.
    Curr Opin Drug Discov Devel; 2005 Sep 15; 8(5):567-76. PubMed ID: 16159018
    [Abstract] [Full Text] [Related]

  • 11. '7TM receptor allostery: putting numbers to shapeshifting proteins.
    Kenakin TP.
    Trends Pharmacol Sci; 2009 Sep 15; 30(9):460-9. PubMed ID: 19729207
    [Abstract] [Full Text] [Related]

  • 12. G-protein-coupled receptors: from classical modes of modulation to allosteric mechanisms.
    Bridges TM, Lindsley CW.
    ACS Chem Biol; 2008 Sep 19; 3(9):530-41. PubMed ID: 18652471
    [Abstract] [Full Text] [Related]

  • 13. Allosteric modulation of G protein-coupled receptors: a pharmacological perspective.
    Keov P, Sexton PM, Christopoulos A.
    Neuropharmacology; 2011 Jan 19; 60(1):24-35. PubMed ID: 20637785
    [Abstract] [Full Text] [Related]

  • 14. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
    Burford NT, Watson J, Bertekap R, Alt A.
    Biochem Pharmacol; 2011 Mar 15; 81(6):691-702. PubMed ID: 21184747
    [Abstract] [Full Text] [Related]

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  • 18. Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development.
    Müller CE, Schiedel AC, Baqi Y.
    Pharmacol Ther; 2012 Sep 15; 135(3):292-315. PubMed ID: 22728155
    [Abstract] [Full Text] [Related]

  • 19. Allosteric modulation of G protein-coupled receptors.
    May LT, Leach K, Sexton PM, Christopoulos A.
    Annu Rev Pharmacol Toxicol; 2007 Sep 15; 47():1-51. PubMed ID: 17009927
    [Abstract] [Full Text] [Related]

  • 20. Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients.
    Wellendorph P, Johansen LD, Bräuner-Osborne H.
    Mol Pharmacol; 2009 Sep 15; 76(3):453-65. PubMed ID: 19487246
    [Abstract] [Full Text] [Related]

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