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Journal Abstract Search
329 related items for PubMed ID: 16889837
21. [G-protein-coupled receptors targeting: the allosteric approach]. Sebag JA, Pantel J. Med Sci (Paris); 2012 Oct; 28(10):845-51. PubMed ID: 23067415 [Abstract] [Full Text] [Related]
22. Seven transmembrane receptors as nature's prototype allosteric protein: de-emphasizing the geography of binding. Kenakin TP. Mol Pharmacol; 2008 Sep; 74(3):541-3. PubMed ID: 18583453 [Abstract] [Full Text] [Related]
23. Allosteric approaches to the targeting of G-protein-coupled receptors for novel drug discovery: a critical assessment. Raddatz R, Schaffhauser H, Marino MJ. Biochem Pharmacol; 2007 Aug 01; 74(3):383-91. PubMed ID: 17572390 [Abstract] [Full Text] [Related]
24. Positive and negative allosteric modulation of metabotropic glutamate receptors: emerging therapeutic potential. Kew JN. Pharmacol Ther; 2004 Dec 01; 104(3):233-44. PubMed ID: 15556676 [Abstract] [Full Text] [Related]
25. New concepts in drug discovery: collateral efficacy and permissive antagonism. Kenakin T. Nat Rev Drug Discov; 2005 Nov 01; 4(11):919-27. PubMed ID: 16264435 [Abstract] [Full Text] [Related]
26. 7TM pharmacology measured by label-free: a holistic approach to cell signalling. Rocheville M, Jerman JC. Curr Opin Pharmacol; 2009 Oct 01; 9(5):643-9. PubMed ID: 19671497 [Abstract] [Full Text] [Related]
27. Bridging the gap: bitopic ligands of G-protein-coupled receptors. Lane JR, Sexton PM, Christopoulos A. Trends Pharmacol Sci; 2013 Jan 01; 34(1):59-66. PubMed ID: 23177916 [Abstract] [Full Text] [Related]
28. Allosteric modulators of G-protein-coupled receptors. May LT, Christopoulos A. Curr Opin Pharmacol; 2003 Oct 01; 3(5):551-6. PubMed ID: 14559102 [Abstract] [Full Text] [Related]
29. G-protein-coupled receptor-focused drug discovery using a target class platform approach. Heilker R, Wolff M, Tautermann CS, Bieler M. Drug Discov Today; 2009 Mar 01; 14(5-6):231-40. PubMed ID: 19121411 [Abstract] [Full Text] [Related]
30. Profiling of orthosteric and allosteric group-III metabotropic glutamate receptor ligands on various G protein-coupled receptors with Tag-lite® assays. Belhocine A, Veglianese P, Hounsou C, Dupuis E, Acher F, Durroux T, Goudet C, Pin JP. Neuropharmacology; 2018 Sep 15; 140():233-245. PubMed ID: 30099051 [Abstract] [Full Text] [Related]
31. Binding of orthosteric ligands to the allosteric site of the M(2) muscarinic cholinergic receptor. Redka DS, Pisterzi LF, Wells JW. Mol Pharmacol; 2008 Sep 15; 74(3):834-43. PubMed ID: 18552124 [Abstract] [Full Text] [Related]
32. The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors. Valant C, Robert Lane J, Sexton PM, Christopoulos A. Annu Rev Pharmacol Toxicol; 2012 Sep 15; 52():153-78. PubMed ID: 21910627 [Abstract] [Full Text] [Related]
34. Allosteric modulation of endogenous metabolites as an avenue for drug discovery. Wootten D, Savage EE, Valant C, May LT, Sloop KW, Ficorilli J, Showalter AD, Willard FS, Christopoulos A, Sexton PM. Mol Pharmacol; 2012 Aug 15; 82(2):281-90. PubMed ID: 22576254 [Abstract] [Full Text] [Related]
38. [GPCRs heterodimerization: a new way towards the discovery of function for the orphan receptors?]. Levoye A, Jockers R. Med Sci (Paris); 2007 Aug 15; 23(8-9):746-50. PubMed ID: 17875294 [Abstract] [Full Text] [Related]