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Journal Abstract Search

200 related items for PubMed ID: 16890251

  • 1. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
    Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M.
    Neuropharmacology; 2006 Sep; 51(4):933-46. PubMed ID: 16890251
    [Abstract] [Full Text] [Related]

  • 2. Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
    Sobol E, Bialer M, Yagen B.
    J Med Chem; 2004 Aug 12; 47(17):4316-26. PubMed ID: 15294003
    [Abstract] [Full Text] [Related]

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  • 4. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
    Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M.
    Epilepsia; 2010 Mar 12; 51(3):323-32. PubMed ID: 19674061
    [Abstract] [Full Text] [Related]

  • 5. Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.
    Okada A, Noyori H, Yagen B, Shimshoni JA, Bialer M, Fujiwara M.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Oct 12; 86(5):394-401. PubMed ID: 19830722
    [Abstract] [Full Text] [Related]

  • 6. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
    Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsia; 2008 Jul 12; 49(7):1202-12. PubMed ID: 18435754
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues.
    Kaufmann D, Bialer M, Shimshoni JA, Devor M, Yagen B.
    J Med Chem; 2009 Nov 26; 52(22):7236-48. PubMed ID: 19877649
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.
    Shekh-Ahmad T, Bialer M, Yavin E.
    Epilepsy Res; 2012 Feb 26; 98(2-3):238-46. PubMed ID: 22057163
    [Abstract] [Full Text] [Related]

  • 9. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
    Shimshoni JA, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2007 Dec 13; 50(25):6419-27. PubMed ID: 17994680
    [Abstract] [Full Text] [Related]

  • 10. Tetramethylcyclopropyl analogue of the leading antiepileptic drug, valproic acid: evaluation of the teratogenic effects of its amide derivatives in NMRI mice.
    Okada A, Onishi Y, Yagen B, Shimshoni JA, Kaufmann D, Bialer M, Fujiwara M.
    Birth Defects Res A Clin Mol Teratol; 2008 Sep 13; 82(9):610-21. PubMed ID: 18671279
    [Abstract] [Full Text] [Related]

  • 11. Preliminary evaluation of the anticonvulsant activity of a valproic acid analog: N-(2-propylpentanoyl) urea.
    Tantisira B, Tantisira MH, Patarapanich C, Sooksawate T, Chunngam T.
    Res Commun Mol Pathol Pharmacol; 1997 Aug 13; 97(2):151-64. PubMed ID: 9344228
    [Abstract] [Full Text] [Related]

  • 12. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
    Pessah N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2009 Apr 23; 52(8):2233-42. PubMed ID: 19296679
    [Abstract] [Full Text] [Related]

  • 13. Efficacy of antiepileptic tetramethylcyclopropyl analogues of valproic acid amides in a rat model of neuropathic pain.
    Winkler I, Sobol E, Yagen B, Steinman A, Devor M, Bialer M.
    Neuropharmacology; 2005 Dec 23; 49(8):1110-20. PubMed ID: 16055160
    [Abstract] [Full Text] [Related]

  • 14. Treatment with valproate after status epilepticus: effect on neuronal damage, epileptogenesis, and behavioral alterations in rats.
    Brandt C, Gastens AM, Sun Mz, Hausknecht M, Löscher W.
    Neuropharmacology; 2006 Sep 23; 51(4):789-804. PubMed ID: 16806297
    [Abstract] [Full Text] [Related]

  • 15. Anticonvulsant activity of BmK AS, a sodium channel site 4-specific modulator.
    Zhao R, Weng CC, Feng Q, Chen L, Zhang XY, Zhu HY, Wang Y, Ji YH.
    Epilepsy Behav; 2011 Feb 23; 20(2):267-76. PubMed ID: 21239233
    [Abstract] [Full Text] [Related]

  • 16. Preclinical profiling and safety studies of ABT-769: a compound with potential for broad-spectrum antiepileptic activity.
    Giardina WJ, Dart MJ, Harris RR, Bitner RS, Radek RJ, Fox GB, Chemburkar SR, Marsh KC, Waring JF, Hui JY, Chen J, Curzon P, Grayson GK, Komater VA, Ku Y, Lockwood M, Miner HM, Nikkel AL, Pan JB, Pu YM, Wang L, Bennani Y, Durmuller N, Jolly R, Roux S, Sullivan JP, Decker MW.
    Epilepsia; 2005 Sep 23; 46(9):1349-61. PubMed ID: 16146429
    [Abstract] [Full Text] [Related]

  • 17. Pharmacokinetics and metabolism of a new potent antiepileptic drug, 2,2,3,3-tetramethycyclopropanecarbonylurea, in rats.
    Sobol E, Yagen B, Winkler I, Britzi M, Gibson D, Bialer M.
    Drug Metab Dispos; 2005 Oct 23; 33(10):1538-46. PubMed ID: 16037415
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives.
    Shimshoni JA, Bialer M, Yagen B.
    Bioorg Med Chem; 2008 Jun 01; 16(11):6297-305. PubMed ID: 18472270
    [Abstract] [Full Text] [Related]

  • 19. Teratology study of derivatives of tetramethylcyclopropyl amide analogues of valproic acid in mice.
    Okada A, Onishi Y, Aoki Y, Yagen B, Sobol E, Bialer M, Fujiwara M.
    Birth Defects Res B Dev Reprod Toxicol; 2006 Jun 01; 77(3):227-33. PubMed ID: 16767757
    [Abstract] [Full Text] [Related]

  • 20. Pharmacodynamic and pharmacokinetic interactions of perampanel and other antiepileptic drugs in a rat amygdala kindling model.
    Wu T, Nagaya Y, Hanada T.
    Seizure; 2014 Oct 01; 23(9):732-9. PubMed ID: 24997072
    [Abstract] [Full Text] [Related]

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