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Journal Abstract Search


964 related items for PubMed ID: 16899113

  • 1. Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.
    Marampon F, Ciccarelli C, Zani BM.
    Mol Cancer; 2006 Aug 09; 5():31. PubMed ID: 16899113
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  • 3. Phosphorylation regulates Myc expression via prolonged activation of the mitogen-activated protein kinase pathway.
    Wang Z, Ge L, Wang M, Carr BI.
    J Cell Physiol; 2006 Jul 09; 208(1):133-40. PubMed ID: 16596619
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  • 4. Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.
    Gysin S, Lee SH, Dean NM, McMahon M.
    Cancer Res; 2005 Jun 01; 65(11):4870-80. PubMed ID: 15930308
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  • 5. MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.
    Marampon F, Bossi G, Ciccarelli C, Di Rocco A, Sacchi A, Pestell RG, Zani BM.
    Mol Cancer Ther; 2009 Mar 01; 8(3):543-51. PubMed ID: 19258428
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  • 6. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.
    J Pharmacol Exp Ther; 2009 Jun 01; 329(3):1063-70. PubMed ID: 19258520
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  • 7. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R, Piperdi S, Gorlick R.
    Clin Cancer Res; 2008 Oct 15; 14(20):6396-404. PubMed ID: 18927278
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  • 8. Differential sensitivity of chemoresistant neuroblastoma subtypes to MAPK-targeted treatment correlates with ERK, p53 expression, and signaling response to U0126.
    Eppstein AC, Sandoval JA, Klein PJ, Woodruff HA, Grosfeld JL, Hickey RJ, Malkas LH, Schmidt CM.
    J Pediatr Surg; 2006 Jan 15; 41(1):252-9. PubMed ID: 16410143
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  • 9. Magnolol elicits activation of the extracellular signal-regulated kinase pathway by inducing p27KIP1-mediated G2/M-phase cell cycle arrest in human urinary bladder cancer 5637 cells.
    Lee SJ, Cho YH, Park K, Kim EJ, Jung KH, Park SS, Kim WJ, Moon SK.
    Biochem Pharmacol; 2008 Jun 15; 75(12):2289-300. PubMed ID: 18468578
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  • 10. Significant anti-proliferation of human endometrial cancer cells by combined treatment with a selective COX-2 inhibitor NS398 and specific MEK inhibitor U0126.
    Gao J, Niwa K, Takemura M, Sun W, Onogi K, Wu Y, Seishima M, Mori H, Tamaya T.
    Int J Oncol; 2005 Mar 15; 26(3):737-44. PubMed ID: 15703831
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  • 15. XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer.
    Yu LF, Wang J, Zou B, Lin MC, Wu YL, Xia HH, Sun YW, Gu Q, He H, Lam SK, Kung HF, Wong BC.
    Cancer; 2007 May 15; 109(10):1996-2003. PubMed ID: 17385215
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  • 17. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.
    Liu L, Cao Y, Chen C, Zhang X, McNabola A, Wilkie D, Wilhelm S, Lynch M, Carter C.
    Cancer Res; 2006 Dec 15; 66(24):11851-8. PubMed ID: 17178882
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  • 18. Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and down-regulation of tumor suppressor p53 and p21WAF1/CIP1.
    Chen C, Chang YC, Liu CL, Chang KJ, Guo IC.
    Breast Cancer Res Treat; 2006 Jul 15; 98(2):121-32. PubMed ID: 16752079
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  • 19. c-Myc protein is stabilized by fibroblast growth factor 2 and destabilized by ACTH to control cell cycle in mouse Y1 adrenocortical cells.
    Lepique AP, Moraes MS, Rocha KM, Eichler CB, Hajj GN, Schwindt TT, Armelin HA.
    J Mol Endocrinol; 2004 Dec 15; 33(3):623-38. PubMed ID: 15591023
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  • 20. Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells.
    Lefevre G, Calipel A, Mouriaux F, Hecquet C, Malecaze F, Mascarelli F.
    Oncogene; 2003 Dec 04; 22(55):8813-22. PubMed ID: 14654778
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