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Journal Abstract Search


333 related items for PubMed ID: 16912073

  • 1. Validating Aurora B as an anti-cancer drug target.
    Girdler F, Gascoigne KE, Eyers PA, Hartmuth S, Crafter C, Foote KM, Keen NJ, Taylor SS.
    J Cell Sci; 2006 Sep 01; 119(Pt 17):3664-75. PubMed ID: 16912073
    [Abstract] [Full Text] [Related]

  • 2. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
    Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS.
    J Cell Biol; 2003 Apr 28; 161(2):267-80. PubMed ID: 12719470
    [Abstract] [Full Text] [Related]

  • 3. Trivalent dimethylarsenic compound induces histone H3 phosphorylation and abnormal localization of Aurora B kinase in HepG2 cells.
    Suzuki T, Miyazaki K, Kita K, Ochi T.
    Toxicol Appl Pharmacol; 2009 Dec 15; 241(3):275-82. PubMed ID: 19716834
    [Abstract] [Full Text] [Related]

  • 4. ZM447439, the Aurora kinase B inhibitor, suppresses the growth of cervical cancer SiHa cells and enhances the chemosensitivity to cisplatin.
    Zhang L, Zhang S.
    J Obstet Gynaecol Res; 2011 Jun 15; 37(6):591-600. PubMed ID: 21159048
    [Abstract] [Full Text] [Related]

  • 5. Development and biological evaluation of a novel aurora A kinase inhibitor.
    Sardon T, Cottin T, Xu J, Giannis A, Vernos I.
    Chembiochem; 2009 Feb 13; 10(3):464-78. PubMed ID: 19199284
    [Abstract] [Full Text] [Related]

  • 6. Small-molecule inhibition of Aurora kinases triggers spindle checkpoint-independent apoptosis in cancer cells.
    Sun L, Li D, Dong X, Yu H, Dong JT, Zhang C, Lu X, Zhou J.
    Biochem Pharmacol; 2008 Mar 01; 75(5):1027-34. PubMed ID: 18163976
    [Abstract] [Full Text] [Related]

  • 7. Antiproliferative effect of Aurora kinase targeting in mesothelioma.
    Crispi S, Fagliarone C, Biroccio A, D'Angelo C, Galati R, Sacchi A, Vincenzi B, Baldi A, Verdina A.
    Lung Cancer; 2010 Dec 01; 70(3):271-9. PubMed ID: 20371132
    [Abstract] [Full Text] [Related]

  • 8. Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity.
    LeRoy PJ, Hunter JJ, Hoar KM, Burke KE, Shinde V, Ruan J, Bowman D, Galvin K, Ecsedy JA.
    Cancer Res; 2007 Jun 01; 67(11):5362-70. PubMed ID: 17545617
    [Abstract] [Full Text] [Related]

  • 9. Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.
    Kaestner P, Stolz A, Bastians H.
    Mol Cancer Ther; 2009 Jul 01; 8(7):2046-56. PubMed ID: 19584233
    [Abstract] [Full Text] [Related]

  • 10. Aurora-A: the maker and breaker of spindle poles.
    Barr AR, Gergely F.
    J Cell Sci; 2007 Sep 01; 120(Pt 17):2987-96. PubMed ID: 17715155
    [Abstract] [Full Text] [Related]

  • 11. MLN8054, an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo.
    Huck JJ, Zhang M, McDonald A, Bowman D, Hoar KM, Stringer B, Ecsedy J, Manfredi MG, Hyer ML.
    Mol Cancer Res; 2010 Mar 01; 8(3):373-84. PubMed ID: 20197380
    [Abstract] [Full Text] [Related]

  • 12. Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase.
    Yang H, Burke T, Dempsey J, Diaz B, Collins E, Toth J, Beckmann R, Ye X.
    FEBS Lett; 2005 Jun 20; 579(16):3385-91. PubMed ID: 15922328
    [Abstract] [Full Text] [Related]

  • 13. Aurora kinases: new targets for cancer therapy.
    Carvajal RD, Tse A, Schwartz GK.
    Clin Cancer Res; 2006 Dec 01; 12(23):6869-75. PubMed ID: 17145803
    [Abstract] [Full Text] [Related]

  • 14. Aurora kinase inhibitors as anti-cancer therapy.
    Lok W, Klein RQ, Saif MW.
    Anticancer Drugs; 2010 Apr 01; 21(4):339-50. PubMed ID: 20016367
    [Abstract] [Full Text] [Related]

  • 15. Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays.
    Manfredi MG, Ecsedy JA, Chakravarty A, Silverman L, Zhang M, Hoar KM, Stroud SG, Chen W, Shinde V, Huck JJ, Wysong DR, Janowick DA, Hyer ML, Leroy PJ, Gershman RE, Silva MD, Germanos MS, Bolen JB, Claiborne CF, Sells TB.
    Clin Cancer Res; 2011 Dec 15; 17(24):7614-24. PubMed ID: 22016509
    [Abstract] [Full Text] [Related]

  • 16. ZM447439, a novel promising aurora kinase inhibitor, provokes antiproliferative and proapoptotic effects alone and in combination with bio- and chemotherapeutic agents in gastroenteropancreatic neuroendocrine tumor cell lines.
    Georgieva I, Koychev D, Wang Y, Holstein J, Hopfenmüller W, Zeitz M, Grabowski P.
    Neuroendocrinology; 2010 Dec 15; 91(2):121-30. PubMed ID: 19923785
    [Abstract] [Full Text] [Related]

  • 17. Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts.
    Gadea BB, Ruderman JV.
    Mol Biol Cell; 2005 Mar 15; 16(3):1305-18. PubMed ID: 15616188
    [Abstract] [Full Text] [Related]

  • 18. Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
    Li M, Jung A, Ganswindt U, Marini P, Friedl A, Daniel PT, Lauber K, Jendrossek V, Belka C.
    Biochem Pharmacol; 2010 Jan 15; 79(2):122-9. PubMed ID: 19686703
    [Abstract] [Full Text] [Related]

  • 19. Therapeutic potential of Aurora kinase inhibitors in cancer.
    Naruganahalli KS, Lakshmanan M, Dastidar SG, Ray A.
    Curr Opin Investig Drugs; 2006 Dec 15; 7(12):1044-51. PubMed ID: 17209521
    [Abstract] [Full Text] [Related]

  • 20. Mitotic drivers--inhibitors of the Aurora B Kinase.
    Keen N, Taylor S.
    Cancer Metastasis Rev; 2009 Jun 15; 28(1-2):185-95. PubMed ID: 19189202
    [Abstract] [Full Text] [Related]


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