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Journal Abstract Search

124 related items for PubMed ID: 16913720

  • 21. Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA.
    Jiang G, Xu Y, Fujiwara Y, Tsukahara T, Tsukahara R, Gajewiak J, Tigyi G, Prestwich GD.
    ChemMedChem; 2007 May; 2(5):679-90. PubMed ID: 17443831
    [Abstract] [Full Text] [Related]

  • 22. Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts.
    Qian Y, Hamilton M, Sidduri A, Gabriel S, Ren Y, Peng R, Kondru R, Narayanan A, Truitt T, Hamid R, Chen Y, Zhang L, Fretland AJ, Sanchez RA, Chang KC, Lucas M, Schoenfeld RC, Laine D, Fuentes ME, Stevenson CS, Budd DC.
    J Med Chem; 2012 Sep 13; 55(17):7920-39. PubMed ID: 22894757
    [Abstract] [Full Text] [Related]

  • 23. Alkoxymethylenephosphonate analogues of (Lyso) phosphatidic acid stimulate signaling networks coupled to the LPA2 receptor.
    Gajewiak J, Tsukahara R, Tsukahara T, Fujiwara Y, Yu S, Lu Y, Murph M, Mills GB, Tigyi G, Prestwich GD.
    ChemMedChem; 2007 Dec 13; 2(12):1789-98. PubMed ID: 17952880
    [Abstract] [Full Text] [Related]

  • 24. Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid.
    Gupte R, Siddam A, Lu Y, Li W, Fujiwara Y, Panupinthu N, Pham TC, Baker DL, Parrill AL, Gotoh M, Murakami-Murofushi K, Kobayashi S, Mills GB, Tigyi G, Miller DD.
    Bioorg Med Chem Lett; 2010 Dec 15; 20(24):7525-8. PubMed ID: 21051230
    [Abstract] [Full Text] [Related]

  • 25. [Cyclic phosphatidic acids and their analogues--unique lipid mediators].
    Grzelczyk A, Koziołkiewicz M.
    Postepy Biochem; 2012 Dec 15; 58(3):327-43. PubMed ID: 23373418
    [Abstract] [Full Text] [Related]

  • 26. Analysis of Edg-Like LPA Receptor-Ligand Interactions.
    Balogh B, Pazmany T, Matyus P.
    Curr Pharm Des; 2015 Dec 15; 21(24):3533-47. PubMed ID: 25686617
    [Abstract] [Full Text] [Related]

  • 27. Synthesis of monofluorinated analogues of lysophosphatidic acid.
    Xu Y, Qian L, Prestwich GD.
    J Org Chem; 2003 Jun 27; 68(13):5320-30. PubMed ID: 12816494
    [Abstract] [Full Text] [Related]

  • 28. Synthesis of alpha-fluorinated phosphonates from alpha-fluorovinylphosphonates: a new route to analogues of lysophosphatidic acid.
    Xu Y, Qian L, Prestwich GD.
    Org Lett; 2003 Jun 26; 5(13):2267-70. PubMed ID: 12816425
    [Abstract] [Full Text] [Related]

  • 29. Participation of analogues of lysophosphatidic acid (LPA): oleoyl-sn-glycero-3-phosphate (L-alpha-LPA) and 1-oleoyl-2-O-methyl-rac-glycerophosphothionate (OMPT) in uterine smooth muscle contractility of the pregnant pigs.
    Markiewicz W, Kamińska K, Bogacki M, Maślanka T, Jaroszewski J.
    Pol J Vet Sci; 2012 Jun 26; 15(4):635-43. PubMed ID: 23390752
    [Abstract] [Full Text] [Related]

  • 30. Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents.
    Beck HP, Kohn T, Rubenstein S, Hedberg C, Schwandner R, Hasslinger K, Dai K, Li C, Liang L, Wesche H, Frank B, An S, Wickramasinghe D, Jaen J, Medina J, Hungate R, Shen W.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):1037-41. PubMed ID: 18178086
    [Abstract] [Full Text] [Related]

  • 31. Dioleoyl phosphatidic acid induces morphological changes through an endogenous LPA receptor in C6 glioma cells.
    Chang YJ, Kim YL, Jo JY, Kyeok K, Kim HL, Im DS.
    Arch Pharm Res; 2008 May 01; 31(5):628-33. PubMed ID: 18481020
    [Abstract] [Full Text] [Related]

  • 32. TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
    Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG.
    J Lipid Res; 2011 Jul 01; 52(7):1307-18. PubMed ID: 21521824
    [Abstract] [Full Text] [Related]

  • 33. Efficient synthesis of 3-O-thia-cPA and preliminary analysis of its biological activity toward autotaxin.
    Tanaka R, Kato M, Suzuki T, Nakazaki A, Nozaki E, Gotoh M, Murakami-Murofushi K, Kobayashi S.
    Bioorg Med Chem Lett; 2011 Jul 15; 21(14):4180-2. PubMed ID: 21676615
    [Abstract] [Full Text] [Related]

  • 34. Protean agonism of the lysophosphatidic acid receptor-1 with Ki16425 reduces nerve growth factor-induced neurite outgrowth in pheochromocytoma 12 cells.
    Moughal NA, Waters CM, Valentine WJ, Connell M, Richardson JC, Tigyi G, Pyne S, Pyne NJ.
    J Neurochem; 2006 Sep 15; 98(6):1920-9. PubMed ID: 16945108
    [Abstract] [Full Text] [Related]

  • 35. Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid.
    Santos WL, Heasley BH, Jarosz R, Carter KM, Lynch KR, Macdonald TL.
    Bioorg Med Chem Lett; 2004 Jul 05; 14(13):3473-6. PubMed ID: 15177455
    [Abstract] [Full Text] [Related]

  • 36. Novel diastereomeric opioid tetrapeptides exhibit differing pharmacological activity profiles.
    Ioja E, Tourwé D, Kertész I, Tóth G, Borsodi A, Benyhe S.
    Brain Res Bull; 2007 Sep 14; 74(1-3):119-29. PubMed ID: 17683797
    [Abstract] [Full Text] [Related]

  • 37. Sphingosine 1-phosphate and lysophosphatidic acid receptors: agonist and antagonist binding and progress toward development of receptor-specific ligands.
    Parrill AL, Sardar VM, Yuan H.
    Semin Cell Dev Biol; 2004 Oct 14; 15(5):467-76. PubMed ID: 15271292
    [Abstract] [Full Text] [Related]

  • 38.
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  • 39. Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist.
    East JE, Carter KM, Kennedy PC, Schulte NA, Toews ML, Lynch KR, Macdonald TL.
    Medchemcomm; 2011 Mar 03; 2(4):325-330. PubMed ID: 22180836
    [Abstract] [Full Text] [Related]

  • 40. Synthesis of chiral (alpha,alpha-difluoroalkyl)phosphonate analogues of (lyso)phosphatidic acid via hydrolytic kinetic resolution.
    Xu Y, Prestwich GD.
    Org Lett; 2002 Nov 14; 4(23):4021-4. PubMed ID: 12423076
    [Abstract] [Full Text] [Related]

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