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Journal Abstract Search

215 related items for PubMed ID: 16928785

  • 1. Rifampin induces the in vitro oxidative metabolism, but not the in vivo clearance of diclofenac in rhesus monkeys.
    Prueksaritanont T, Li C, Tang C, Kuo Y, Strong-Basalyga K, Carr B.
    Drug Metab Dispos; 2006 Nov; 34(11):1806-10. PubMed ID: 16928785
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  • 2. In vitro and in vivo CYP3A64 induction and inhibition studies in rhesus monkeys: a preclinical approach for CYP3A-mediated drug interaction studies.
    Prueksaritanont T, Kuo Y, Tang C, Li C, Qiu Y, Lu B, Strong-Basalyga K, Richards K, Carr B, Lin JH.
    Drug Metab Dispos; 2006 Sep; 34(9):1546-55. PubMed ID: 16782766
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  • 3. Interaction of diclofenac and quinidine in monkeys: stimulation of diclofenac metabolism.
    Tang W, Stearns RA, Kwei GY, Iliff SA, Miller RR, Egan MA, Yu NX, Dean DC, Kumar S, Shou M, Lin JH, Baillie TA.
    J Pharmacol Exp Ther; 1999 Dec; 291(3):1068-74. PubMed ID: 10565826
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  • 4. Extrapolation of diclofenac clearance from in vitro microsomal metabolism data: role of acyl glucuronidation and sequential oxidative metabolism of the acyl glucuronide.
    Kumar S, Samuel K, Subramanian R, Braun MP, Stearns RA, Chiu SH, Evans DC, Baillie TA.
    J Pharmacol Exp Ther; 2002 Dec; 303(3):969-78. PubMed ID: 12438516
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  • 11. Altered AZT (3'-azido-3'-deoxythymidine) glucuronidation kinetics in liver microsomes as an explanation for underprediction of in vivo clearance: comparison to hepatocytes and effect of incubation environment.
    Engtrakul JJ, Foti RS, Strelevitz TJ, Fisher MB.
    Drug Metab Dispos; 2005 Nov; 33(11):1621-7. PubMed ID: 16049128
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  • 12. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS, Hatch HL, Kosea F, Nguyen HT, Choo EF, McClure KF, Taylor TJ, Henne KR, Kuperman AV, Dombroski MA, Letavic MA.
    Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
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  • 13. Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans.
    Dean BJ, Chang S, Silva Elipe MV, Xia YQ, Braun M, Soli E, Zhao Y, Franklin RB, Karanam B.
    Drug Metab Dispos; 2007 Feb; 35(2):283-92. PubMed ID: 17132765
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  • 15. Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes.
    Lam JL, Benet LZ.
    Drug Metab Dispos; 2004 Nov; 32(11):1311-6. PubMed ID: 15483198
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  • 20. Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey.
    Sharer JE, Shipley LA, Vandenbranden MR, Binkley SN, Wrighton SA.
    Drug Metab Dispos; 1995 Nov; 23(11):1231-41. PubMed ID: 8591724
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