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Journal Abstract Search

323 related items for PubMed ID: 16936720

  • 1. Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy.
    Putt KS, Chen GW, Pearson JM, Sandhorst JS, Hoagland MS, Kwon JT, Hwang SK, Jin H, Churchwell MI, Cho MH, Doerge DR, Helferich WG, Hergenrother PJ.
    Nat Chem Biol; 2006 Oct; 2(10):543-50. PubMed ID: 16936720
    [Abstract] [Full Text] [Related]

  • 2. Flipping the safety catch of procaspase-3.
    Porter AG.
    Nat Chem Biol; 2006 Oct; 2(10):509-10. PubMed ID: 16983381
    [No Abstract] [Full Text] [Related]

  • 3. Procaspase-activating compound 1 induces a caspase-3-dependent cell death in cerebellar granule neurons.
    Aziz G, Akselsen ØW, Hansen TV, Paulsen RE.
    Toxicol Appl Pharmacol; 2010 Sep 15; 247(3):238-42. PubMed ID: 20638399
    [Abstract] [Full Text] [Related]

  • 4. Cell death induced by novel procaspase-3 activators can be reduced by growth factors.
    Boldingh Debernard KA, Aziz G, Gjesvik AT, Paulsen RE.
    Biochem Biophys Res Commun; 2011 Sep 23; 413(2):364-9. PubMed ID: 21893038
    [Abstract] [Full Text] [Related]

  • 5. Targeting procaspase-3 with WF-208, a novel PAC-1 derivative, causes selective cancer cell apoptosis.
    Wang F, Liu Y, Wang L, Yang J, Zhao Y, Wang N, Cao Q, Gong P, Wu C.
    J Cell Mol Med; 2015 Aug 23; 19(8):1916-28. PubMed ID: 25754465
    [Abstract] [Full Text] [Related]

  • 6. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
    Hoch U, Lynch J, Sato Y, Kashimoto S, Kajikawa F, Furutani Y, Silverman JA.
    Cancer Chemother Pharmacol; 2009 Jun 23; 64(1):53-65. PubMed ID: 18931998
    [Abstract] [Full Text] [Related]

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  • 8. Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3.
    Peterson QP, Hsu DC, Goode DR, Novotny CJ, Totten RK, Hergenrother PJ.
    J Med Chem; 2009 Sep 24; 52(18):5721-31. PubMed ID: 19708658
    [Abstract] [Full Text] [Related]

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  • 10. Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.
    Hamaï A, Richon C, Meslin F, Faure F, Kauffmann A, Lecluse Y, Jalil A, Larue L, Avril MF, Chouaib S, Mehrpour M.
    Oncogene; 2006 Dec 07; 25(58):7618-34. PubMed ID: 16983347
    [Abstract] [Full Text] [Related]

  • 11. Caspase-1 as a radio- and chemo-sensitiser in vitro and in vivo.
    Martín-Duque P, Quintanilla M, McNeish I, Lopes R, Romero J, Romero D, Lemoine NR, Ramón y Cajal S, Vassaux G.
    Int J Mol Med; 2006 May 07; 17(5):841-7. PubMed ID: 16596269
    [Abstract] [Full Text] [Related]

  • 12. Targeting executioner procaspase-3 with the procaspase-activating compound B-PAC-1 induces apoptosis in multiple myeloma cells.
    Zaman S, Wang R, Gandhi V.
    Exp Hematol; 2015 Nov 07; 43(11):951-962.e3. PubMed ID: 26257207
    [Abstract] [Full Text] [Related]

  • 13. Human urine extract CDA-2 induces apoptosis of myelodysplastic syndrome-derived MUTZ-1 cells through the PI3K/Akt signaling pathway in a caspase-3-dependent manner.
    Huang J, Yang M, Liu H, Jin J.
    Acta Pharmacol Sin; 2008 Aug 07; 29(8):951-64. PubMed ID: 18664328
    [Abstract] [Full Text] [Related]

  • 14. Pharmacokinetics and derivation of an anticancer dosing regimen for PAC-1, a preferential small molecule activator of procaspase-3, in healthy dogs.
    Lucas PW, Schmit JM, Peterson QP, West DC, Hsu DC, Novotny CJ, Dirikolu L, Churchwell MI, Doerge DR, Garrett LD, Hergenrother PJ, Fan TM.
    Invest New Drugs; 2011 Oct 07; 29(5):901-11. PubMed ID: 20499133
    [Abstract] [Full Text] [Related]

  • 15. Dual small-molecule targeting of procaspase-3 dramatically enhances zymogen activation and anticancer activity.
    Botham RC, Fan TM, Im I, Borst LB, Dirikolu L, Hergenrother PJ.
    J Am Chem Soc; 2014 Jan 29; 136(4):1312-9. PubMed ID: 24383395
    [Abstract] [Full Text] [Related]

  • 16. Antitumor activity of 3,5,4'-trimethoxystilbene in COLO 205 cells and xenografts in SCID mice.
    Pan MH, Gao JH, Lai CS, Wang YJ, Chen WM, Lo CY, Wang M, Dushenkov S, Ho CT.
    Mol Carcinog; 2008 Mar 29; 47(3):184-96. PubMed ID: 18085528
    [Abstract] [Full Text] [Related]

  • 17. Mitochondria-mediated and p53-associated apoptosis induced in human cancer cells by a novel selenophene derivative, D-501036.
    Shiah HS, Lee WS, Juang SH, Hong PC, Lung CC, Chang CJ, Chou KM, Chang JY.
    Biochem Pharmacol; 2007 Mar 01; 73(5):610-9. PubMed ID: 17150195
    [Abstract] [Full Text] [Related]

  • 18. Induction of apoptosis by pectenotoxin-2 is mediated with the induction of DR4/DR5, Egr-1 and NAG-1, activation of caspases and modulation of the Bcl-2 family in p53-deficient Hep3B hepatocellular carcinoma cells.
    Shin DY, Kim GY, Kim ND, Jung JH, Kim SK, Kang HS, Choi YH.
    Oncol Rep; 2008 Feb 01; 19(2):517-26. PubMed ID: 18202802
    [Abstract] [Full Text] [Related]

  • 19. Molecular evidence of Zn chelation of the procaspase activating compound B-PAC-1 in B cell lymphoma.
    Sarkar A, Balakrishnan K, Chen J, Patel V, Neelapu SS, McMurray JS, Gandhi V.
    Oncotarget; 2016 Jan 19; 7(3):3461-76. PubMed ID: 26658105
    [Abstract] [Full Text] [Related]

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