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194 related items for PubMed ID: 16937423
1. Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups. Kurosaki H, Yamaguchi Y, Yasuzawa H, Jin W, Yamagata Y, Arakawa Y. ChemMedChem; 2006 Sep; 1(9):969-72. PubMed ID: 16937423 [No Abstract] [Full Text] [Related]
6. Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols. Liénard BM, Garau G, Horsfall L, Karsisiotis AI, Damblon C, Lassaux P, Papamicael C, Roberts GC, Galleni M, Dideberg O, Frère JM, Schofield CJ. Org Biomol Chem; 2008 Jul 07; 6(13):2282-94. PubMed ID: 18563261 [Abstract] [Full Text] [Related]
7. Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors. Liénard BM, Hüting R, Lassaux P, Galleni M, Frère JM, Schofield CJ. J Med Chem; 2008 Feb 14; 51(3):684-8. PubMed ID: 18205296 [Abstract] [Full Text] [Related]
8. Spirocyclopropyl beta-lactams as mechanism-based inhibitors of serine beta-lactamases. Synthesis by rhodium-catalyzed cyclopropanation of 6-diazopenicillanate sulfone. Sandanayaka VP, Prashad AS, Yang Y, Williamson RT, Lin YI, Mansour TS. J Med Chem; 2003 Jun 19; 46(13):2569-71. PubMed ID: 12801220 [Abstract] [Full Text] [Related]
9. O-aryloxycarbonyl hydroxamates: new beta-lactamase inhibitors that cross-link the active site. Wyrembak PN, Babaoglu K, Pelto RB, Shoichet BK, Pratt RF. J Am Chem Soc; 2007 Aug 08; 129(31):9548-9. PubMed ID: 17628063 [No Abstract] [Full Text] [Related]
11. Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates. Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR. J Med Chem; 2004 Dec 16; 47(26):6556-68. PubMed ID: 15588091 [Abstract] [Full Text] [Related]
12. Spectroscopic and biochemical characterization of metallo-β-lactamase IMP-1 with dicarboxylic, sulfonyl, and thiol inhibitors. Zhang H, Yang K, Cheng Z, Thomas C, Steinbrunner A, Pryor C, Vulcan M, Kemp C, Orea D, Paththamperuma C, Chen AY, Cohen SM, Page RC, Tierney DL, Crowder MW. Bioorg Med Chem; 2021 Jun 15; 40():116183. PubMed ID: 33965839 [Abstract] [Full Text] [Related]
13. Zinc-bound thiolate-disulfide exchange: a strategy for inhibiting metallo-beta-lactamases. Boerzel H, Koeckert M, Bu W, Spingler B, Lippard SJ. Inorg Chem; 2003 Mar 10; 42(5):1604-15. PubMed ID: 12611529 [Abstract] [Full Text] [Related]
14. Inhibitors of metallo-beta-lactamase generated from beta-lactam antibiotics. Badarau A, Llinás A, Laws AP, Damblon C, Page MI. Biochemistry; 2005 Jun 21; 44(24):8578-89. PubMed ID: 15952764 [Abstract] [Full Text] [Related]
15. Complexes of thiomandelate and captopril mercaptocarboxylate inhibitors to metallo-beta-lactamase by polarizable molecular mechanics. Validation on model binding sites by quantum chemistry. Antony J, Piquemal JP, Gresh N. J Comput Chem; 2005 Aug 21; 26(11):1131-47. PubMed ID: 15937993 [Abstract] [Full Text] [Related]
18. Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). Sun D, Wang Z, Di Y, Jaen JC, Labelle M, Ma J, Miao S, Sudom A, Tang L, Tomooka CS, Tu H, Ursu S, Walker N, Yan X, Ye Q, Powers JP. Bioorg Med Chem Lett; 2008 Jun 15; 18(12):3513-6. PubMed ID: 18511278 [Abstract] [Full Text] [Related]
19. Combined mass spectrometry and dynamic chemistry approach to identify metalloenzyme inhibitors. Liénard BM, Selevsek N, Oldham NJ, Schofield CJ. ChemMedChem; 2007 Feb 15; 2(2):175-9. PubMed ID: 17206734 [No Abstract] [Full Text] [Related]
20. Comparative study of the inhibition of metallo-beta-lactamases (IMP-1 and VIM-2) by thiol compounds that contain a hydrophobic group. Jin W, Arakawa Y, Yasuzawa H, Taki T, Hashiguchi R, Mitsutani K, Shoga A, Yamaguchi Y, Kurosaki H, Shibata N, Ohta M, Goto M. Biol Pharm Bull; 2004 Jun 15; 27(6):851-6. PubMed ID: 15187432 [Abstract] [Full Text] [Related] Page: [Next] [New Search]