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Journal Abstract Search


175 related items for PubMed ID: 16939683

  • 1. Site-dependent contributions of P-glycoprotein and CYP3A to cyclosporin A absorption, and effect of dexamethasone in small intestine of mice.
    Jin M, Shimada T, Yokogawa K, Nomura M, Ishizaki J, Piao Y, Kato Y, Tsuji A, Miyamoto K.
    Biochem Pharmacol; 2006 Oct 16; 72(8):1042-50. PubMed ID: 16939683
    [Abstract] [Full Text] [Related]

  • 2. Contributions of intestinal P-glycoprotein and CYP3A to oral bioavailability of cyclosporin A in mice treated with or without dexamethasone.
    Jin M, Shimada T, Yokogawa K, Nomura M, Kato Y, Tsuji A, Miyamoto K.
    Int J Pharm; 2006 Feb 17; 309(1-2):81-6. PubMed ID: 16384676
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  • 3. Brain cyclosporin A levels are determined by ontogenic regulation of mdr1a expression.
    Goralski KB, Acott PD, Fraser AD, Worth D, Sinal CJ.
    Drug Metab Dispos; 2006 Feb 17; 34(2):288-95. PubMed ID: 16303871
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  • 4. Modulation of mdr1a and CYP3A gene expression in the intestine and liver as possible cause of changes in the cyclosporin A disposition kinetics by dexamethasone.
    Yokogawa K, Shimada T, Higashi Y, Itoh Y, Masue T, Ishizaki J, Asahi M, Miyamoto K.
    Biochem Pharmacol; 2002 Feb 15; 63(4):777-83. PubMed ID: 11992648
    [Abstract] [Full Text] [Related]

  • 5. Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug.
    Jonker JW, Wagenaar E, van Deemter L, Gottschlich R, Bender HM, Dasenbrock J, Schinkel AH.
    Br J Pharmacol; 1999 May 15; 127(1):43-50. PubMed ID: 10369454
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  • 6. P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387.
    Durmus S, Xu N, Sparidans RW, Wagenaar E, Beijnen JH, Schinkel AH.
    Pharmacol Res; 2013 Oct 15; 76():9-16. PubMed ID: 23827160
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  • 9. Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily mRNAS in small intestine.
    Takara K, Ohnishi N, Horibe S, Yokoyama T.
    Drug Metab Dispos; 2003 Oct 15; 31(10):1235-9. PubMed ID: 12975332
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  • 10. Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra.
    Cao J, Chen X, Liang J, Yu XQ, Xu AL, Chan E, Wei D, Huang M, Wen JY, Yu XY, Li XT, Sheu FS, Zhou SF.
    Drug Metab Dispos; 2007 Apr 15; 35(4):539-53. PubMed ID: 17220245
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  • 14. Minor compensatory changes in SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats do not detract from their utility in the study of transporter-mediated pharmacokinetics.
    Zamek-Gliszczynski MJ, Goldstein KM, Paulman A, Baker TK, Ryan TP.
    Drug Metab Dispos; 2013 Jun 15; 41(6):1174-8. PubMed ID: 23569176
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  • 15. Effect of organophosphate pesticide diazinon on expression and activity of intestinal P-glycoprotein.
    Lecoeur S, Videmann B, Mazallon M.
    Toxicol Lett; 2006 Mar 01; 161(3):200-9. PubMed ID: 16221533
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  • 17. Impact of P-glycoprotein and breast cancer resistance protein on the brain distribution of antiepileptic drugs in knockout mouse models.
    Nakanishi H, Yonezawa A, Matsubara K, Yano I.
    Eur J Pharmacol; 2013 Jun 15; 710(1-3):20-8. PubMed ID: 23588114
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  • 19. Disposition of the cholesterol absorption inhibitor ezetimibe in mdr1a/b (-/-) mice.
    Oswald S, Koll C, Siegmund W.
    J Pharm Sci; 2007 Dec 15; 96(12):3478-84. PubMed ID: 17828742
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  • 20. The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice.
    Zhou L, Schmidt K, Nelson FR, Zelesky V, Troutman MD, Feng B.
    Drug Metab Dispos; 2009 May 15; 37(5):946-55. PubMed ID: 19225039
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