These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

610 related items for PubMed ID: 16945988

  • 1. Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype.
    Kiang TK, Ho PC, Anari MR, Tong V, Abbott FS, Chang TK.
    Toxicol Sci; 2006 Dec; 94(2):261-71. PubMed ID: 16945988
    [Abstract] [Full Text] [Related]

  • 2. Effect of Ginkgo biloba extract on oxidative metabolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype.
    Numa AM, Abbott FS, Chang TK.
    Can J Physiol Pharmacol; 2007 Sep; 85(9):848-55. PubMed ID: 18066130
    [Abstract] [Full Text] [Related]

  • 3. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H, White RB, Stevens JC.
    Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
    [Abstract] [Full Text] [Related]

  • 4. Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.
    Jacobson PA, Green K, Birnbaum A, Remmel RP.
    Cancer Chemother Pharmacol; 2002 Jun; 49(6):461-7. PubMed ID: 12107550
    [Abstract] [Full Text] [Related]

  • 5. The influence of cytochrome oxidase CYP2A6, CYP2B6, and CYP2C9 polymorphisms on the plasma concentrations of valproic acid in epileptic patients.
    Tan L, Yu JT, Sun YP, Ou JR, Song JH, Yu Y.
    Clin Neurol Neurosurg; 2010 May; 112(4):320-3. PubMed ID: 20089352
    [Abstract] [Full Text] [Related]

  • 6. Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes.
    Rifkind AB, Lee C, Chang TK, Waxman DJ.
    Arch Biochem Biophys; 1995 Jul 10; 320(2):380-9. PubMed ID: 7625847
    [Abstract] [Full Text] [Related]

  • 7. Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes.
    Ho PC, Abbott FS, Zanger UM, Chang TK.
    Pharmacogenomics J; 2003 Jul 10; 3(6):335-42. PubMed ID: 14597963
    [Abstract] [Full Text] [Related]

  • 8. Human CYP2C9 and CYP2A6 mediate formation of the hepatotoxin 4-ene-valproic acid.
    Sadeque AJ, Fisher MB, Korzekwa KR, Gonzalez FJ, Rettie AE.
    J Pharmacol Exp Ther; 1997 Nov 10; 283(2):698-703. PubMed ID: 9353388
    [Abstract] [Full Text] [Related]

  • 9. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X, Wang JS, Kivistö KT, Neuvonen PJ, Backman JT.
    Br J Clin Pharmacol; 2001 Nov 10; 52(5):547-53. PubMed ID: 11736863
    [Abstract] [Full Text] [Related]

  • 10. Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes.
    Bae SH, Kwon MJ, Choi EJ, Zheng YF, Yoon KD, Liu KH, Bae SK.
    Chem Biol Interact; 2013 Sep 05; 205(1):11-9. PubMed ID: 23777987
    [Abstract] [Full Text] [Related]

  • 11. Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes.
    Court MH, Duan SX, Hesse LM, Venkatakrishnan K, Greenblatt DJ.
    Anesthesiology; 2001 Jan 05; 94(1):110-9. PubMed ID: 11135730
    [Abstract] [Full Text] [Related]

  • 12. Effects of irsogladine on P450-isoform specific activities in human hepatic microsomes.
    Nakamura A, Tougou K, Kitazumi H, Yamada T, Honjou K, Nonaka K, Mukai H.
    Arzneimittelforschung; 2006 Jan 05; 56(7):547-52. PubMed ID: 16927538
    [Abstract] [Full Text] [Related]

  • 13. Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation.
    Code EL, Crespi CL, Penman BW, Gonzalez FJ, Chang TK, Waxman DJ.
    Drug Metab Dispos; 1997 Aug 05; 25(8):985-93. PubMed ID: 9280407
    [Abstract] [Full Text] [Related]

  • 14. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.
    Xenobiotica; 2000 Oct 05; 30(10):955-69. PubMed ID: 11315104
    [Abstract] [Full Text] [Related]

  • 15. Cyp2a6 is a principal enzyme involved in hydroxylation of 1,7-dimethylxanthine, a main caffeine metabolite, in humans.
    Kimura M, Yamazaki H, Fujieda M, Kiyotani K, Honda G, Saruwatari J, Nakagawa K, Ishizaki T, Kamataki T.
    Drug Metab Dispos; 2005 Sep 05; 33(9):1361-6. PubMed ID: 15980104
    [Abstract] [Full Text] [Related]

  • 16. CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with recombinant enzymes.
    Hidestrand M, Oscarson M, Salonen JS, Nyman L, Pelkonen O, Turpeinen M, Ingelman-Sundberg M.
    Drug Metab Dispos; 2001 Nov 05; 29(11):1480-4. PubMed ID: 11602525
    [Abstract] [Full Text] [Related]

  • 17. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
    Ramírez J, Innocenti F, Schuetz EG, Flockhart DA, Relling MV, Santucci R, Ratain MJ.
    Drug Metab Dispos; 2004 Sep 05; 32(9):930-6. PubMed ID: 15319333
    [Abstract] [Full Text] [Related]

  • 18. Metabolism of (-)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes.
    Miyazawa M, Gyoubu K.
    Xenobiotica; 2007 Feb 05; 37(2):194-204. PubMed ID: 17484521
    [Abstract] [Full Text] [Related]

  • 19. Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition.
    Sahi J, Black CB, Hamilton GA, Zheng X, Jolley S, Rose KA, Gilbert D, LeCluyse EL, Sinz MW.
    Drug Metab Dispos; 2003 Apr 05; 31(4):439-46. PubMed ID: 12642470
    [Abstract] [Full Text] [Related]

  • 20. Involvement of CYP2A6 in the formation of a novel metabolite, 3-hydroxypilocarpine, from pilocarpine in human liver microsomes.
    Endo T, Ban M, Hirata K, Yamamoto A, Hara Y, Momose Y.
    Drug Metab Dispos; 2007 Mar 05; 35(3):476-83. PubMed ID: 17178767
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 31.