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155 related items for PubMed ID: 1694703

  • 1. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysis.
    Whitehead VM, Rosenblatt DS, Vuchich MJ, Shuster JJ, Witte A, Beaulieu D.
    Blood; 1990 Jul 01; 76(1):44-9. PubMed ID: 1694703
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  • 2. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Vuchich MJ, Lauer SJ, Mahoney D, Carroll AJ, Shuster JJ, Esseltine DW, Payment C, Look AT, Akabutu J.
    Blood; 1992 Sep 01; 80(5):1316-23. PubMed ID: 1381244
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  • 3. Methotrexate polyglutamate synthesis in lymphoblasts from children with acute lymphoblastic leukemia.
    Whitehead VM, Rosenblatt DS, Vuchich MJ, Beaulieu D.
    Dev Pharmacol Ther; 1987 Sep 01; 10(6):443-8. PubMed ID: 2445535
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  • 6. Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study.
    Whitehead VM, Vuchich MJ, Cooley LD, Lauer SJ, Mahoney DH, Shuster JJ, Payment C, Koch PA, Akabutu JJ, Bowen T, Kamen BA, Ravindranath Y, Emami A, Look AT, Beardsley GP, Pullen DJ, Camitta B.
    Leuk Lymphoma; 1998 Nov 01; 31(5-6):507-19. PubMed ID: 9922041
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  • 7. Methotrexate polyglutamation may lack prognostic significance in children with B-cell precursor acute lymphoblastic leukemia treated with intensive oral methotrexate.
    Mantadakis E, Smith AK, Hynan L, Winick NJ, Kamen BA.
    J Pediatr Hematol Oncol; 2002 Nov 01; 24(8):636-42. PubMed ID: 12439035
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  • 8. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Shuster JJ, Vuchich MJ, Mahoney DH, Lauer SJ, Payment C, Koch PA, Cooley LD, Look AT, Pullen DJ, Camitta B.
    Leukemia; 2005 Apr 01; 19(4):533-6. PubMed ID: 15716987
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  • 10. Time course of methotrexate polyglutamate formation and degradation in the pre-B-leukaemia cell line Nalm6 and in lymphoblasts from children with leukaemia.
    Buchholz B, Frei E, Eisenbarth J, Weigand M, Ludwig R.
    Eur J Cancer; 1996 Nov 01; 32A(12):2101-7. PubMed ID: 9014752
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  • 11. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
    Masson E, Relling MV, Synold TW, Liu Q, Schuetz JD, Sandlund JT, Pui CH, Evans WE.
    J Clin Invest; 1996 Jan 01; 97(1):73-80. PubMed ID: 8550853
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  • 17. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
    Synold TW, Relling MV, Boyett JM, Rivera GK, Sandlund JT, Mahmoud H, Crist WM, Pui CH, Evans WE.
    J Clin Invest; 1994 Nov 01; 94(5):1996-2001. PubMed ID: 7525652
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  • 18. Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease.
    Göker E, Lin JT, Trippett T, Elisseyeff Y, Tong WP, Niedzwiecki D, Tan C, Steinherz P, Schweitzer BI, Bertino JR.
    Leukemia; 1993 Jul 01; 7(7):1000-4. PubMed ID: 7686600
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  • 19. Evidence for negative feedback of extracellular methotrexate on blasts of acute lymphoblastic leukemia in vitro.
    Hum MC, Smith AK, Lark RH, Winick NJ, Kamen BA.
    Pharmacotherapy; 1997 Jul 01; 17(6):1260-6. PubMed ID: 9399609
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  • 20. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.
    Galpin AJ, Schuetz JD, Masson E, Yanishevski Y, Synold TW, Barredo JC, Pui CH, Relling MV, Evans WE.
    Mol Pharmacol; 1997 Jul 01; 52(1):155-63. PubMed ID: 9224825
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