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144 related items for PubMed ID: 16952134

  • 1. Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists.
    Jurk M, Kritzler A, Debelak H, Vollmer J, Krieg AM, Uhlmann E.
    ChemMedChem; 2006 Sep; 1(9):1007-14. PubMed ID: 16952134
    [Abstract] [Full Text] [Related]

  • 2. Agonists of Toll-like receptor 9 containing synthetic dinucleotide motifs.
    Yu D, Putta MR, Bhagat L, Li Y, Zhu F, Wang D, Tang JX, Kandimalla ER, Agrawal S.
    J Med Chem; 2007 Dec 13; 50(25):6411-8. PubMed ID: 17988082
    [Abstract] [Full Text] [Related]

  • 3. Novel oligodeoxynucleotide agonists of TLR9 containing N3-Me-dC or N1-Me-dG modifications.
    Putta MR, Zhu F, Li Y, Bhagat L, Cong Y, Kandimalla ER, Agrawal S.
    Nucleic Acids Res; 2006 Dec 13; 34(11):3231-8. PubMed ID: 16798912
    [Abstract] [Full Text] [Related]

  • 4. Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.
    Vollmer J, Weeratna RD, Jurk M, Davis HL, Schetter C, Wüllner M, Wader T, Liu M, Kritzler A, Krieg AM.
    J Leukoc Biol; 2004 Sep 13; 76(3):585-93. PubMed ID: 15218053
    [Abstract] [Full Text] [Related]

  • 5. Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.
    Kandimalla ER, Bhagat L, Li Y, Yu D, Wang D, Cong YP, Song SS, Tang JX, Sullivan T, Agrawal S.
    Proc Natl Acad Sci U S A; 2005 May 10; 102(19):6925-30. PubMed ID: 15860583
    [Abstract] [Full Text] [Related]

  • 6. Recent advances in the development of immunostimulatory oligonucleotides.
    Uhlmann E, Vollmer J.
    Curr Opin Drug Discov Devel; 2003 Mar 10; 6(2):204-17. PubMed ID: 12669456
    [Abstract] [Full Text] [Related]

  • 7. Impact of nature and length of linker incorporated in agonists on toll-like receptor 9-mediated immune responses.
    Putta MR, Yu D, Bhagat L, Wang D, Zhu FG, Kandimalla ER.
    J Med Chem; 2010 May 13; 53(9):3730-8. PubMed ID: 20361743
    [Abstract] [Full Text] [Related]

  • 8. Modifications incorporated in CpG motifs of oligodeoxynucleotides lead to antagonist activity of toll-like receptors 7 and 9.
    Yu D, Wang D, Zhu FG, Bhagat L, Dai M, Kandimalla ER, Agrawal S.
    J Med Chem; 2009 Aug 27; 52(16):5108-14. PubMed ID: 19650625
    [Abstract] [Full Text] [Related]

  • 9. TLR9 agonists as adjuvants for prophylactic and therapeutic vaccines.
    Daubenberger CA.
    Curr Opin Mol Ther; 2007 Feb 27; 9(1):45-52. PubMed ID: 17330401
    [Abstract] [Full Text] [Related]

  • 10. Synthetic methylated CpG ODNs are potent in vivo adjuvants when delivered in liposomal nanoparticles.
    Chikh G, de Jong SD, Sekirov L, Raney SG, Kazem M, Wilson KD, Cullis PR, Dutz JP, Tam YK.
    Int Immunol; 2009 Jul 27; 21(7):757-67. PubMed ID: 19502586
    [Abstract] [Full Text] [Related]

  • 11. Oligodeoxyribonucleotide-based antagonists for Toll-like receptors 7 and 9.
    Wang D, Bhagat L, Yu D, Zhu FG, Tang JX, Kandimalla ER, Agrawal S.
    J Med Chem; 2009 Jan 22; 52(2):551-8. PubMed ID: 19102653
    [Abstract] [Full Text] [Related]

  • 12. Toll-like receptors involved in the response to microbial pathogens: development of agonists for toll-like receptor 9.
    Schetter C, Vollmer J.
    Curr Opin Drug Discov Devel; 2004 Mar 22; 7(2):204-10. PubMed ID: 15603254
    [Abstract] [Full Text] [Related]

  • 13. The critical DNA flanking sequences of a CpG oligodeoxynucleotide, but not the 6 base CpG motif, can be replaced with RNA without quantitative or qualitative changes in Toll-like receptor 9-mediated activity.
    Sen G, Flora M, Chattopadhyay G, Klinman DM, Lees A, Mond JJ, Snapper CM.
    Cell Immunol; 2004 Mar 22; 232(1-2):64-74. PubMed ID: 15922717
    [Abstract] [Full Text] [Related]

  • 14. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition.
    Bauer S, Kirschning CJ, Häcker H, Redecke V, Hausmann S, Akira S, Wagner H, Lipford GB.
    Proc Natl Acad Sci U S A; 2001 Jul 31; 98(16):9237-42. PubMed ID: 11470918
    [Abstract] [Full Text] [Related]

  • 15. Immunostimulatory CpG oligonucleotides form defined three-dimensional structures: results from an NMR study.
    He G, Patra A, Siegmund K, Peter M, Heeg K, Dalpke A, Richert C.
    ChemMedChem; 2007 Apr 31; 2(4):549-60. PubMed ID: 17366653
    [Abstract] [Full Text] [Related]

  • 16. Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity.
    Merrell MA, Ilvesaro JM, Lehtonen N, Sorsa T, Gehrs B, Rosenthal E, Chen D, Shackley B, Harris KW, Selander KS.
    Mol Cancer Res; 2006 Jul 31; 4(7):437-47. PubMed ID: 16849519
    [Abstract] [Full Text] [Related]

  • 17. Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides.
    Brownlie R, Zhu J, Allan B, Mutwiri GK, Babiuk LA, Potter A, Griebel P.
    Mol Immunol; 2009 Sep 31; 46(15):3163-70. PubMed ID: 19573927
    [Abstract] [Full Text] [Related]

  • 18. The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation.
    Haas T, Metzger J, Schmitz F, Heit A, Müller T, Latz E, Wagner H.
    Immunity; 2008 Mar 31; 28(3):315-23. PubMed ID: 18342006
    [Abstract] [Full Text] [Related]

  • 19. Cross-talk between toll-like receptors 5 and 9 on activation of human immune responses.
    Merlo A, Calcaterra C, Mènard S, Balsari A.
    J Leukoc Biol; 2007 Sep 31; 82(3):509-18. PubMed ID: 17586660
    [Abstract] [Full Text] [Related]

  • 20. Toll-like receptor 9 mediates CpG oligonucleotide-induced cellular invasion.
    Ilvesaro JM, Merrell MA, Li L, Wakchoure S, Graves D, Brooks S, Rahko E, Jukkola-Vuorinen A, Vuopala KS, Harris KW, Selander KS.
    Mol Cancer Res; 2008 Oct 31; 6(10):1534-43. PubMed ID: 18922969
    [Abstract] [Full Text] [Related]

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