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68 related items for PubMed ID: 16955484

  • 1. The immunosuppressant rapamycin exacerbates neurotoxicity of Abeta peptide.
    Lafay-Chebassier C, Pérault-Pochat MC, Page G, Rioux Bilan A, Damjanac M, Pain S, Houeto JL, Gil R, Hugon J.
    J Neurosci Res; 2006 Nov 01; 84(6):1323-34. PubMed ID: 16955484
    [Abstract] [Full Text] [Related]

  • 2. mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease.
    Lafay-Chebassier C, Paccalin M, Page G, Barc-Pain S, Perault-Pochat MC, Gil R, Pradier L, Hugon J.
    J Neurochem; 2005 Jul 01; 94(1):215-25. PubMed ID: 15953364
    [Abstract] [Full Text] [Related]

  • 3. Amyloid-beta interrupts the PI3K-Akt-mTOR signaling pathway that could be involved in brain-derived neurotrophic factor-induced Arc expression in rat cortical neurons.
    Chen TJ, Wang DC, Chen SS.
    J Neurosci Res; 2009 Aug 01; 87(10):2297-307. PubMed ID: 19301428
    [Abstract] [Full Text] [Related]

  • 4. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
    Fang CX, Yang X, Sreejayan N, Ren J.
    Exp Neurol; 2007 Jan 01; 203(1):196-204. PubMed ID: 16962100
    [Abstract] [Full Text] [Related]

  • 5. Protective effects of S-nitrosoglutathione against amyloid beta-peptide neurotoxicity.
    Ju TC, Chen SD, Liu CC, Yang DI.
    Free Radic Biol Med; 2005 Apr 01; 38(7):938-49. PubMed ID: 15749390
    [Abstract] [Full Text] [Related]

  • 6. Alzheimer's amyloid beta-peptide (1-42) induces cell death in human neuroblastoma via bax/bcl-2 ratio increase: an intriguing role for methionine 35.
    Clementi ME, Pezzotti M, Orsini F, Sampaolese B, Mezzogori D, Grassi C, Giardina B, Misiti F.
    Biochem Biophys Res Commun; 2006 Mar 31; 342(1):206-13. PubMed ID: 16472763
    [Abstract] [Full Text] [Related]

  • 7. Octreotide and the mTOR inhibitor RAD001 (everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumour cell Line.
    Grozinsky-Glasberg S, Franchi G, Teng M, Leontiou CA, Ribeiro de Oliveira A, Dalino P, Salahuddin N, Korbonits M, Grossman AB.
    Neuroendocrinology; 2008 Mar 31; 87(3):168-81. PubMed ID: 18025810
    [Abstract] [Full Text] [Related]

  • 8. An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR.
    Hou G, Xue L, Lu Z, Fan T, Tian F, Xue Y.
    Cancer Lett; 2007 Aug 18; 253(2):236-48. PubMed ID: 17360108
    [Abstract] [Full Text] [Related]

  • 9. Activated alpha2macroglobulin increases beta-amyloid (25-35)-induced toxicity in LAN5 human neuroblastoma cells.
    Fabrizi C, Businaro R, Lauro GM, Starace G, Fumagalli L.
    Exp Neurol; 1999 Feb 18; 155(2):252-9. PubMed ID: 10072300
    [Abstract] [Full Text] [Related]

  • 10. Rapamycin is a neuroprotective treatment for traumatic brain injury.
    Erlich S, Alexandrovich A, Shohami E, Pinkas-Kramarski R.
    Neurobiol Dis; 2007 Apr 18; 26(1):86-93. PubMed ID: 17270455
    [Abstract] [Full Text] [Related]

  • 11. Memantine protects rat cortical cultured neurons against beta-amyloid-induced toxicity by attenuating tau phosphorylation.
    Song MS, Rauw G, Baker GB, Kar S.
    Eur J Neurosci; 2008 Nov 18; 28(10):1989-2002. PubMed ID: 19046381
    [Abstract] [Full Text] [Related]

  • 12. Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.
    Feng W, Brown RE, Trung CD, Li W, Wang L, Khoury T, Alrawi S, Yao J, Xia K, Tan D.
    Ann Clin Lab Sci; 2008 Nov 18; 38(3):195-209. PubMed ID: 18715846
    [Abstract] [Full Text] [Related]

  • 13. IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways.
    Bibollet-Bahena O, Almazan G.
    J Neurochem; 2009 Jun 18; 109(5):1440-51. PubMed ID: 19453943
    [Abstract] [Full Text] [Related]

  • 14. S100B protects LAN-5 neuroblastoma cells against Abeta amyloid-induced neurotoxicity via RAGE engagement at low doses but increases Abeta amyloid neurotoxicity at high doses.
    Businaro R, Leone S, Fabrizi C, Sorci G, Donato R, Lauro GM, Fumagalli L.
    J Neurosci Res; 2006 Apr 18; 83(5):897-906. PubMed ID: 16477616
    [Abstract] [Full Text] [Related]

  • 15. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways.
    Aoki H, Takada Y, Kondo S, Sawaya R, Aggarwal BB, Kondo Y.
    Mol Pharmacol; 2007 Jul 18; 72(1):29-39. PubMed ID: 17395690
    [Abstract] [Full Text] [Related]

  • 16. The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation.
    Follo MY, Mongiorgi S, Bosi C, Cappellini A, Finelli C, Chiarini F, Papa V, Libra M, Martinelli G, Cocco L, Martelli AM.
    Cancer Res; 2007 May 01; 67(9):4287-94. PubMed ID: 17483341
    [Abstract] [Full Text] [Related]

  • 17. Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling.
    Wang Y, Zhao Q, Ma S, Yang F, Gong Y, Ke C.
    IUBMB Life; 2007 Nov 01; 59(11):717-21. PubMed ID: 17968710
    [Abstract] [Full Text] [Related]

  • 18. Activation of the protein p7OS6K via ERK phosphorylation by cholinergic muscarinic receptors stimulation in human neuroblastoma cells and in mice brain.
    Deguil J, Perault-Pochat MC, Chavant F, Lafay-Chebassier C, Fauconneau B, Pain S.
    Toxicol Lett; 2008 Nov 10; 182(1-3):91-6. PubMed ID: 18809477
    [Abstract] [Full Text] [Related]

  • 19. Substitution of methionine 35 inhibits apoptotic effects of Abeta(31-35) and Abeta(25-35) fragments of amyloid-beta protein in PC12 cells.
    Clementi ME, Misiti F.
    Med Sci Monit; 2005 Nov 10; 11(11):BR381-5. PubMed ID: 16258386
    [Abstract] [Full Text] [Related]

  • 20. mTOR as a potential therapeutic target for treatment of keloids and excessive scars.
    Ong CT, Khoo YT, Mukhopadhyay A, Do DV, Lim IJ, Aalami O, Phan TT.
    Exp Dermatol; 2007 May 10; 16(5):394-404. PubMed ID: 17437482
    [Abstract] [Full Text] [Related]

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