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Journal Abstract Search

148 related items for PubMed ID: 16956907

  • 1. EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells.
    Moiseeva EP, Heukers R, Manson MM.
    Carcinogenesis; 2007 Feb; 28(2):435-45. PubMed ID: 16956907
    [Abstract] [Full Text] [Related]

  • 2. Indole-3-carbinol-induced modulation of NF-kappaB signalling is breast cancer cell-specific and does not correlate with cell death.
    Moiseeva EP, Heukers R.
    Breast Cancer Res Treat; 2008 Jun; 109(3):451-62. PubMed ID: 17653853
    [Abstract] [Full Text] [Related]

  • 3. Indole-3-carbinol-induced death in cancer cells involves EGFR downregulation and is exacerbated in a 3D environment.
    Moiseeva EP, Fox LH, Howells LM, Temple LA, Manson MM.
    Apoptosis; 2006 May; 11(5):799-812. PubMed ID: 16532375
    [Abstract] [Full Text] [Related]

  • 4. Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.
    Cover CM, Hsieh SJ, Tran SH, Hallden G, Kim GS, Bjeldanes LF, Firestone GL.
    J Biol Chem; 1998 Feb 13; 273(7):3838-47. PubMed ID: 9461564
    [Abstract] [Full Text] [Related]

  • 5. A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines.
    Brandi G, Paiardini M, Cervasi B, Fiorucci C, Filippone P, De Marco C, Zaffaroni N, Magnani M.
    Cancer Res; 2003 Jul 15; 63(14):4028-36. PubMed ID: 12874002
    [Abstract] [Full Text] [Related]

  • 6. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.
    Chinni SR, Li Y, Upadhyay S, Koppolu PK, Sarkar FH.
    Oncogene; 2001 May 24; 20(23):2927-36. PubMed ID: 11420705
    [Abstract] [Full Text] [Related]

  • 7. Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells.
    Caruso JA, Campana R, Wei C, Su CH, Hanks AM, Bornmann WG, Keyomarsi K.
    Cell Cycle; 2014 May 24; 13(16):2587-99. PubMed ID: 25486199
    [Abstract] [Full Text] [Related]

  • 8. Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells.
    Rahman KM, Aranha O, Glazyrin A, Chinni SR, Sarkar FH.
    Oncogene; 2000 Nov 23; 19(50):5764-71. PubMed ID: 11126363
    [Abstract] [Full Text] [Related]

  • 9. 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells.
    Nguyen HH, Lavrenov SN, Sundar SN, Nguyen DH, Tseng M, Marconett CN, Kung J, Staub RE, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.
    Chem Biol Interact; 2010 Aug 05; 186(3):255-66. PubMed ID: 20570586
    [Abstract] [Full Text] [Related]

  • 10. Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells.
    Biscardi JS, Belsches AP, Parsons SJ.
    Mol Carcinog; 1998 Apr 05; 21(4):261-72. PubMed ID: 9585256
    [Abstract] [Full Text] [Related]

  • 11. Down-regulation of c-Src/EGFR-mediated signaling activation is involved in the honokiol-induced cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells.
    Park EJ, Min HY, Chung HJ, Hong JY, Kang YJ, Hung TM, Youn UJ, Kim YS, Bae K, Kang SS, Lee SK.
    Cancer Lett; 2009 May 18; 277(2):133-40. PubMed ID: 19135778
    [Abstract] [Full Text] [Related]

  • 12. Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
    Aronchik I, Chen T, Durkin KA, Horwitz MS, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.
    Mol Carcinog; 2012 Nov 18; 51(11):881-94. PubMed ID: 22012859
    [Abstract] [Full Text] [Related]

  • 13. Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.
    Marconett CN, Sundar SN, Tseng M, Tin AS, Tran KQ, Mahuron KM, Bjeldanes LF, Firestone GL.
    Carcinogenesis; 2011 Sep 18; 32(9):1315-23. PubMed ID: 21693539
    [Abstract] [Full Text] [Related]

  • 14. EGFR-c-Src-Mediated HDAC3 Phosphorylation Exacerbates Invasion of Breast Cancer Cells.
    Kwak SM, Seo J, Hwang JT, Sung GJ, Song JH, Jeong JH, Lee SH, Yoon HG, Choi HK, Choi KC.
    Cells; 2019 Aug 19; 8(8):. PubMed ID: 31430896
    [Abstract] [Full Text] [Related]

  • 15. Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells.
    Cover CM, Hsieh SJ, Cram EJ, Hong C, Riby JE, Bjeldanes LF, Firestone GL.
    Cancer Res; 1999 Mar 15; 59(6):1244-51. PubMed ID: 10096555
    [Abstract] [Full Text] [Related]

  • 16. The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing.
    Nguyen HH, Aronchik I, Brar GA, Nguyen DH, Bjeldanes LF, Firestone GL.
    Proc Natl Acad Sci U S A; 2008 Dec 16; 105(50):19750-5. PubMed ID: 19064917
    [Abstract] [Full Text] [Related]

  • 17. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
    Brew CT, Aronchik I, Hsu JC, Sheen JH, Dickson RB, Bjeldanes LF, Firestone GL.
    Int J Cancer; 2006 Feb 15; 118(4):857-68. PubMed ID: 16152627
    [Abstract] [Full Text] [Related]

  • 18. Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells.
    Mueller KL, Hunter LA, Ethier SP, Boerner JL.
    Cancer Res; 2008 May 01; 68(9):3314-22. PubMed ID: 18451158
    [Abstract] [Full Text] [Related]

  • 19. Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK.
    Cuadrado A, Garcia-Fernandez LF, Gonzalez L, Suarez Y, Losada A, Alcaide V, Martinez T, Fernandez-Sousa JM, Sanchez-Puelles JM, Munoz A.
    J Biol Chem; 2003 Jan 03; 278(1):241-50. PubMed ID: 12414812
    [Abstract] [Full Text] [Related]

  • 20. N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells.
    Jump SM, Kung J, Staub R, Kinseth MA, Cram EJ, Yudina LN, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.
    Biochem Pharmacol; 2008 Feb 01; 75(3):713-24. PubMed ID: 18023427
    [Abstract] [Full Text] [Related]

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