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Journal Abstract Search


107 related items for PubMed ID: 16957420

  • 1. MEK1/2 inhibition promotes Taxotere lethality in mammary tumors in vivo.
    Yacoub A, Gilfor D, Hawkins W, Park MA, Hanna D, Hagan MP, Curiel DT, Fisher PB, Grant S, Dent P.
    Cancer Biol Ther; 2006 Oct; 5(10):1332-9. PubMed ID: 16957420
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  • 2. Transient exposure of mammary tumors to PD184352 and UCN-01 causes tumor cell death in vivo and prolonged suppression of tumor regrowth.
    Hawkins W, Mitchell C, McKinstry R, Gilfor D, Starkey J, Dai Y, Dawson K, Ramakrishnan V, Roberts JD, Yacoub A, Grant S, Dent P.
    Cancer Biol Ther; 2005 Nov; 4(11):1275-84. PubMed ID: 16319524
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  • 3. Sequence dependent exposure of mammary carcinoma cells to Taxotere and the MEK1/2 inhibitor U0126 causes enhanced cell killing in vitro.
    Yacoub A, Han SI, Caron R, Gilfor D, Mooberry S, Grant S, Dent P.
    Cancer Biol Ther; 2003 Nov; 2(6):670-6. PubMed ID: 14688474
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  • 6. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
    Menendez JA, Vellon L, Colomer R, Lupu R.
    Int J Cancer; 2005 May 20; 115(1):19-35. PubMed ID: 15657900
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  • 7. Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression.
    Menendez JA, Ropero S, Lupu R, Colomer R.
    Oncol Rep; 2004 Jun 20; 11(6):1241-52. PubMed ID: 15138562
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  • 8. Comparative in vitro cytotoxicity of taxol and Taxotere against cisplatin-sensitive and -resistant human ovarian carcinoma cell lines.
    Kelland LR, Abel G.
    Cancer Chemother Pharmacol; 1992 Jun 20; 30(6):444-50. PubMed ID: 1356649
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  • 9. 'Rings' of F-actin form around the nucleus in cultured human MCF7 adenocarcinoma cells upon exposure to both taxol and taxotere.
    Rosenblum MD, Shivers RR.
    Comp Biochem Physiol C Toxicol Pharmacol; 2000 Jan 20; 125(1):121-31. PubMed ID: 11790336
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  • 10. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
    Yu C, Krystal G, Varticovksi L, McKinstry R, Rahmani M, Dent P, Grant S.
    Cancer Res; 2002 Jan 01; 62(1):188-99. PubMed ID: 11782377
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  • 11. Enhancing CHK1 inhibitor lethality in glioblastoma.
    Tang Y, Dai Y, Grant S, Dent P.
    Cancer Biol Ther; 2012 Apr 01; 13(6):379-88. PubMed ID: 22313687
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  • 12. Inactivation of NF-kappaB by 3,3'-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells.
    Rahman KM, Ali S, Aboukameel A, Sarkar SH, Wang Z, Philip PA, Sakr WA, Raz A.
    Mol Cancer Ther; 2007 Oct 01; 6(10):2757-65. PubMed ID: 17913854
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  • 16. Targeted nanoassembly loaded with docetaxel improves intracellular drug delivery and efficacy in murine breast cancer model.
    Gao Y, Chen L, Gu W, Xi Y, Lin L, Li Y.
    Mol Pharm; 2008 Oct 01; 5(6):1044-54. PubMed ID: 19434922
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  • 17. Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-17.
    Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, Iwadare H, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu I, Nakayama A, Sasazawa Y, Tashiro E, Imoto M, Kurakata S.
    Anticancer Drugs; 2012 Jan 01; 23(1):119-30. PubMed ID: 22008853
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  • 18. In vitro comparative evaluation of trastuzumab (Herceptin) combined with paclitaxel (Taxol) or docetaxel (Taxotere) in HER2-expressing human breast cancer cell lines.
    Merlin JL, Barberi-Heyob M, Bachmann N.
    Ann Oncol; 2002 Nov 01; 13(11):1743-8. PubMed ID: 12419746
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  • 19. The farnesyl protein transferase inhibitor SCH66336 synergizes with taxanes in vitro and enhances their antitumor activity in vivo.
    Shi B, Yaremko B, Hajian G, Terracina G, Bishop WR, Liu M, Nielsen LL.
    Cancer Chemother Pharmacol; 2000 Nov 01; 46(5):387-93. PubMed ID: 11127943
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