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1150 related items for PubMed ID: 16962653

  • 1. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
    Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B.
    Cell; 2006 Oct 06; 127(1):125-37. PubMed ID: 16962653
    [Abstract] [Full Text] [Related]

  • 2. Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes.
    Kudchodkar SB, Yu Y, Maguire TG, Alwine JC.
    Proc Natl Acad Sci U S A; 2006 Sep 19; 103(38):14182-7. PubMed ID: 16959881
    [Abstract] [Full Text] [Related]

  • 3. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY, Kim DH, Jun CB, Kim YM, Haar EV, Lee SI, Hegg JW, Bandhakavi S, Griffin TJ, Kim DH.
    J Biol Chem; 2007 Aug 31; 282(35):25604-12. PubMed ID: 17599906
    [Abstract] [Full Text] [Related]

  • 4. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
    Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM.
    Dev Cell; 2006 Dec 31; 11(6):859-71. PubMed ID: 17141160
    [Abstract] [Full Text] [Related]

  • 5. Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.
    Yang Q, Inoki K, Ikenoue T, Guan KL.
    Genes Dev; 2006 Oct 15; 20(20):2820-32. PubMed ID: 17043309
    [Abstract] [Full Text] [Related]

  • 6. Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy.
    Léger B, Cartoni R, Praz M, Lamon S, Dériaz O, Crettenand A, Gobelet C, Rohmer P, Konzelmann M, Luthi F, Russell AP.
    J Physiol; 2006 Nov 01; 576(Pt 3):923-33. PubMed ID: 16916907
    [Abstract] [Full Text] [Related]

  • 7. mTOR-rictor is the Ser473 kinase for AKT1 in mouse one-cell stage embryos.
    Zhang Z, Zhang G, Xu X, Su W, Yu B.
    Mol Cell Biochem; 2012 Feb 01; 361(1-2):249-57. PubMed ID: 22057724
    [Abstract] [Full Text] [Related]

  • 8. Rictor, an mTORC2 Protein, Regulates Murine Lymphatic Valve Formation Through the AKT-FOXO1 Signaling.
    Banerjee R, Knauer LA, Iyer D, Barlow SE, Shalaby H, Dehghan R, Scallan JP, Yang Y.
    Arterioscler Thromb Vasc Biol; 2024 Sep 01; 44(9):2004-2023. PubMed ID: 39087350
    [Abstract] [Full Text] [Related]

  • 9. Rapamycin regulates the phosphorylation of rictor.
    Akcakanat A, Singh G, Hung MC, Meric-Bernstam F.
    Biochem Biophys Res Commun; 2007 Oct 19; 362(2):330-3. PubMed ID: 17707343
    [Abstract] [Full Text] [Related]

  • 10. SIN1, a critical component of the mTOR-Rictor complex, is overexpressed and associated with AKT activation in medullary and aggressive papillary thyroid carcinomas.
    Moraitis D, Karanikou M, Liakou C, Dimas K, Tzimas G, Tseleni-Balafouta S, Patsouris E, Rassidakis GZ, Kouvaraki MA.
    Surgery; 2014 Dec 19; 156(6):1542-8; discussion 1548-9. PubMed ID: 25456951
    [Abstract] [Full Text] [Related]

  • 11. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
    Sarbassov DD, Guertin DA, Ali SM, Sabatini DM.
    Science; 2005 Feb 18; 307(5712):1098-101. PubMed ID: 15718470
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W.
    Jeon YH, Park YH, Kwon JH, Lee JH, Kim IY.
    Biochim Biophys Acta; 2013 Oct 18; 1833(10):2135-42. PubMed ID: 23680186
    [Abstract] [Full Text] [Related]

  • 13. Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2.
    Li W, Petrimpol M, Molle KD, Hall MN, Battegay EJ, Humar R.
    Circ Res; 2007 Jan 05; 100(1):79-87. PubMed ID: 17110594
    [Abstract] [Full Text] [Related]

  • 14. Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40.
    Vander Haar E, Lee SI, Bandhakavi S, Griffin TJ, Kim DH.
    Nat Cell Biol; 2007 Mar 05; 9(3):316-23. PubMed ID: 17277771
    [Abstract] [Full Text] [Related]

  • 15. Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival.
    Riaz A, Zeller KS, Johansson S.
    PLoS One; 2012 Mar 05; 7(2):e32081. PubMed ID: 22384145
    [Abstract] [Full Text] [Related]

  • 16. Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.
    Rosner M, Hengstschläger M.
    Hum Mol Genet; 2008 Oct 01; 17(19):2934-48. PubMed ID: 18614546
    [Abstract] [Full Text] [Related]

  • 17. Identification of rictor as a novel substrate of Polo-like kinase 1.
    Shao T, Liu X.
    Cell Cycle; 2015 Oct 01; 14(5):755-60. PubMed ID: 25714006
    [Abstract] [Full Text] [Related]

  • 18. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
    Wang S, Amato KR, Song W, Youngblood V, Lee K, Boothby M, Brantley-Sieders DM, Chen J.
    Mol Cell Biol; 2015 Apr 01; 35(7):1299-313. PubMed ID: 25582201
    [Abstract] [Full Text] [Related]

  • 19. Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation.
    Wang X, Yue P, Kim YA, Fu H, Khuri FR, Sun SY.
    Cancer Res; 2008 Sep 15; 68(18):7409-18. PubMed ID: 18794129
    [Abstract] [Full Text] [Related]

  • 20. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM, Alessi DR.
    Biochem J; 2008 Dec 15; 416(3):375-85. PubMed ID: 18925875
    [Abstract] [Full Text] [Related]

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