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3. The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain. Lam PY, Sublett JE, Hollenbach AD, Roussel MF. Mol Cell Biol; 1999 Jan; 19(1):594-601. PubMed ID: 9858583 [Abstract] [Full Text] [Related]
4. PAX3/forkhead homolog in rhabdomyosarcoma oncoprotein activates glucose transporter 4 gene expression in vivo and in vitro. Armoni M, Quon MJ, Maor G, Avigad S, Shapiro DN, Harel C, Esposito D, Goshen Y, Yaniv I, Karnieli E. J Clin Endocrinol Metab; 2002 Nov; 87(11):5312-24. PubMed ID: 12414908 [Abstract] [Full Text] [Related]
7. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene. Khan J, Bittner ML, Saal LH, Teichmann U, Azorsa DO, Gooden GC, Pavan WJ, Trent JM, Meltzer PS. Proc Natl Acad Sci U S A; 1999 Nov 09; 96(23):13264-9. PubMed ID: 10557309 [Abstract] [Full Text] [Related]
8. Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor. Epstein JA, Song B, Lakkis M, Wang C. Mol Cell Biol; 1998 Jul 09; 18(7):4118-30. PubMed ID: 9632796 [Abstract] [Full Text] [Related]
9. Wild type PAX3 protein and the PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains. Bennicelli JL, Fredericks WJ, Wilson RB, Rauscher FJ, Barr FG. Oncogene; 1995 Jul 06; 11(1):119-30. PubMed ID: 7624119 [Abstract] [Full Text] [Related]
10. The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3. Fredericks WJ, Galili N, Mukhopadhyay S, Rovera G, Bennicelli J, Barr FG, Rauscher FJ. Mol Cell Biol; 1995 Mar 06; 15(3):1522-35. PubMed ID: 7862145 [Abstract] [Full Text] [Related]
11. Transgenic mice expressing PAX3-FKHR have multiple defects in muscle development, including ectopic skeletal myogenesis in the developing neural tube. Finckenstein FG, Davicioni E, Osborn KG, Cavenee WK, Arden KC, Anderson MJ. Transgenic Res; 2006 Oct 06; 15(5):595-614. PubMed ID: 16952014 [Abstract] [Full Text] [Related]
12. Analysis of genetic events that modulate the oncogenic and growth suppressive activities of the PAX3-FKHR fusion oncoprotein. Xia SJ, Rajput P, Strzelecki DM, Barr FG. Lab Invest; 2007 Apr 06; 87(4):318-25. PubMed ID: 17297479 [Abstract] [Full Text] [Related]
13. The alveolar rhabdomyosarcoma PAX3/FKHR fusion protein is a transcriptional activator. Sublett JE, Jeon IS, Shapiro DN. Oncogene; 1995 Aug 03; 11(3):545-52. PubMed ID: 7630639 [Abstract] [Full Text] [Related]
14. Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma. Barr FG. Oncogene; 2001 Sep 10; 20(40):5736-46. PubMed ID: 11607823 [Abstract] [Full Text] [Related]
15. Co-expression of alternatively spliced forms of PAX3, PAX7, PAX3-FKHR and PAX7-FKHR with distinct DNA binding and transactivation properties in rhabdomyosarcoma. Du S, Lawrence EJ, Strzelecki D, Rajput P, Xia SJ, Gottesman DM, Barr FG. Int J Cancer; 2005 May 20; 115(1):85-92. PubMed ID: 15688409 [Abstract] [Full Text] [Related]
16. Analysis of the transforming and growth suppressive activities of the PAX3-FKHR oncoprotein. Xia SJ, Barr FG. Oncogene; 2004 Sep 09; 23(41):6864-71. PubMed ID: 15286710 [Abstract] [Full Text] [Related]
17. An engineered PAX3-KRAB transcriptional repressor inhibits the malignant phenotype of alveolar rhabdomyosarcoma cells harboring the endogenous PAX3-FKHR oncogene. Fredericks WJ, Ayyanathan K, Herlyn M, Friedman JR, Rauscher FJ. Mol Cell Biol; 2000 Jul 09; 20(14):5019-31. PubMed ID: 10866659 [Abstract] [Full Text] [Related]
18. The PAX3-FKHR fusion gene of rhabdomyosarcoma cooperates with loss of p16INK4A to promote bypass of cellular senescence. Linardic CM, Naini S, Herndon JE, Kesserwan C, Qualman SJ, Counter CM. Cancer Res; 2007 Jul 15; 67(14):6691-9. PubMed ID: 17638879 [Abstract] [Full Text] [Related]
19. PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma. Bennicelli JL, Advani S, Schäfer BW, Barr FG. Oncogene; 1999 Jul 29; 18(30):4348-56. PubMed ID: 10439042 [Abstract] [Full Text] [Related]
20. Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma. Taulli R, Scuoppo C, Bersani F, Accornero P, Forni PE, Miretti S, Grinza A, Allegra P, Schmitt-Ney M, Crepaldi T, Ponzetto C. Cancer Res; 2006 May 01; 66(9):4742-9. PubMed ID: 16651427 [Abstract] [Full Text] [Related] Page: [Next] [New Search]