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467 related items for PubMed ID: 16968653

  • 1. Designed ATRA analogue active against ATRA-resistant acute promyelocytic leukemia cells having a single nucleotide substitution in their retinoic acid receptor.
    Komura N, Ikeda Y, Masuda N, Umezawa Y, Ito K, Kizaki M, Umezawa K.
    Leuk Res; 2007 Mar; 31(3):301-13. PubMed ID: 16968653
    [Abstract] [Full Text] [Related]

  • 2. New chemical strategies for overcoming ATRA resistance in APL cells.
    Coradini D.
    Leuk Res; 2007 Mar; 31(3):291-2. PubMed ID: 16919330
    [No Abstract] [Full Text] [Related]

  • 3. Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization.
    Nason-Burchenal K, Maerz W, Albanell J, Allopenna J, Martin P, Moore MA, Dmitrovsky E.
    Differentiation; 1997 Aug; 61(5):321-31. PubMed ID: 9342843
    [Abstract] [Full Text] [Related]

  • 4. Alteration in the cellular response to retinoic acid of a human acute promyelocytic leukemia cell line, UF-1, carrying a patient-derived mutant PML-RARalpha chimeric gene.
    Sato A, Imaizumi M, Hoshi Y, Rikiishi T, Fujii K, Kizaki M, Kagechika H, Kakizuka A, Hayashi Y, Iinuma K.
    Leuk Res; 2004 Sep; 28(9):959-67. PubMed ID: 15234573
    [Abstract] [Full Text] [Related]

  • 5. Differential gene expression in retinoic acid-induced differentiation of acute promyelocytic leukemia cells, NB4 and HL-60 cells.
    Lee KH, Chang MY, Ahn JI, Yu DH, Jung SS, Choi JH, Noh YH, Lee YS, Ahn MJ.
    Biochem Biophys Res Commun; 2002 Sep 06; 296(5):1125-33. PubMed ID: 12207890
    [Abstract] [Full Text] [Related]

  • 6. PML/RARα-Regulated miR-181a/b Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia.
    Bräuer-Hartmann D, Hartmann JU, Wurm AA, Gerloff D, Katzerke C, Verga Falzacappa MV, Pelicci PG, Müller-Tidow C, Tenen DG, Niederwieser D, Behre G.
    Cancer Res; 2015 Aug 15; 75(16):3411-24. PubMed ID: 26041820
    [Abstract] [Full Text] [Related]

  • 7. Enhancement of caffeic acid phenethyl ester on all-trans retinoic acid-induced differentiation in human leukemia HL-60 cells.
    Kuo HC, Kuo WH, Lee YJ, Wang CJ, Tseng TH.
    Toxicol Appl Pharmacol; 2006 Oct 01; 216(1):80-8. PubMed ID: 16766008
    [Abstract] [Full Text] [Related]

  • 8. Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites.
    Idres N, Benoît G, Flexor MA, Lanotte M, Chabot GG.
    Cancer Res; 2001 Jan 15; 61(2):700-5. PubMed ID: 11212271
    [Abstract] [Full Text] [Related]

  • 9. Rosmarinic acid potentiates ATRA-induced macrophage differentiation in acute promyelocytic leukemia NB4 cells.
    Heo SK, Noh EK, Yoon DJ, Jo JC, Koh S, Baek JH, Park JH, Min YJ, Kim H.
    Eur J Pharmacol; 2015 Jan 15; 747():36-44. PubMed ID: 25481858
    [Abstract] [Full Text] [Related]

  • 10. Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis.
    Manikam SD, Stanslas J.
    J Pharm Pharmacol; 2009 Jan 15; 61(1):69-78. PubMed ID: 19126299
    [Abstract] [Full Text] [Related]

  • 11. WEB-2086 and WEB-2170 trigger apoptosis in both ATRA-sensitive and -resistant promyelocytic leukemia cells and greatly enhance ATRA differentiation potential.
    Laurenzana A, Cellai C, Vannucchi AM, Pancrazzi A, Romanelli MN, Paoletti F.
    Leukemia; 2005 Mar 15; 19(3):390-5. PubMed ID: 15674364
    [Abstract] [Full Text] [Related]

  • 12. Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia.
    Cai X, Shen YL, Zhu Q, Jia PM, Yu Y, Zhou L, Huang Y, Zhang JW, Xiong SM, Chen SJ, Wang ZY, Chen Z, Chen GQ.
    Leukemia; 2000 Feb 15; 14(2):262-70. PubMed ID: 10673743
    [Abstract] [Full Text] [Related]

  • 13. Mutations in the E-domain of RAR portion of the PML/RAR chimeric gene may confer clinical resistance to all-trans retinoic acid in acute promyelocytic leukemia.
    Imaizumi M, Suzuki H, Yoshinari M, Sato A, Saito T, Sugawara A, Tsuchiya S, Hatae Y, Fujimoto T, Kakizuka A, Konno T, Iinuma K.
    Blood; 1998 Jul 15; 92(2):374-82. PubMed ID: 9657734
    [Abstract] [Full Text] [Related]

  • 14. Restoration of CCAAT enhancer binding protein α P42 induces myeloid differentiation and overcomes all-trans retinoic acid resistance in human acute promyelocytic leukemia NB4-R1 cells.
    Wang L, Xiao H, Zhang X, Liao W, Fu S, Huang H.
    Int J Oncol; 2015 Nov 15; 47(5):1685-95. PubMed ID: 26397153
    [Abstract] [Full Text] [Related]

  • 15. Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression.
    Xu K, Guidez F, Glasow A, Chung D, Petrie K, Stegmaier K, Wang KK, Zhang J, Jing Y, Zelent A, Waxman S.
    Cancer Res; 2005 Sep 01; 65(17):7856-65. PubMed ID: 16140955
    [Abstract] [Full Text] [Related]

  • 16. Src family kinase inhibitor PP2 enhances differentiation of acute promyelocytic leukemia cell line induced by combination of all-trans-retinoic acid and arsenic trioxide.
    Jung YS, Cheong HJ, Kim SJ, Kim KH, Lee N, Park HS, Won JH.
    Leuk Res; 2014 Aug 01; 38(8):977-82. PubMed ID: 24953245
    [Abstract] [Full Text] [Related]

  • 17. Tyrosine kinase inhibitor STI571 potentiates the pharmacologic activity of retinoic acid in acute promyelocytic leukemia cells: effects on the degradation of RARalpha and PML-RARalpha.
    Gianni' M, Kalaç Y, Ponzanelli I, Rambaldi A, Terao M, Garattini E.
    Blood; 2001 May 15; 97(10):3234-43. PubMed ID: 11342454
    [Abstract] [Full Text] [Related]

  • 18. Apoptosis inducing and differentiation enhancement effect of oridonin on the all-trans-retinoic acid-sensitive and -resistant acute promyelocytic leukemia cells.
    Gao F, Tang Q, Yang P, Fang Y, Li W, Wu Y.
    Int J Lab Hematol; 2010 Feb 15; 32(1 Pt 1):e114-22. PubMed ID: 19302235
    [Abstract] [Full Text] [Related]

  • 19. Benzodithiophenes induce differentiation and apoptosis in human leukemia cells.
    Jing Y, Hellinger N, Xia L, Monks A, Sausville EA, Zelent A, Waxman S.
    Cancer Res; 2005 Sep 01; 65(17):7847-55. PubMed ID: 16140954
    [Abstract] [Full Text] [Related]

  • 20. all-trans-Retinoic acid-induced expression and regulation of retinoic acid 4-hydroxylase (CYP26) in human promyelocytic leukemia.
    Ozpolat B, Mehta K, Tari AM, Lopez-Berestein G.
    Am J Hematol; 2002 May 01; 70(1):39-47. PubMed ID: 11994980
    [Abstract] [Full Text] [Related]

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