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254 related items for PubMed ID: 16970395
1. Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition. Oikonomakos NG, Tiraidis C, Leonidas DD, Zographos SE, Kristiansen M, Jessen CU, Nørskov-Lauritsen L, Agius L. J Med Chem; 2006 Sep 21; 49(19):5687-701. PubMed ID: 16970395 [Abstract] [Full Text] [Related]
2. Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states. Mitchell EP, Withers SG, Ermert P, Vasella AT, Garman EF, Oikonomakos NG, Johnson LN. Biochemistry; 1996 Jun 11; 35(23):7341-55. PubMed ID: 8652510 [Abstract] [Full Text] [Related]
3. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate. Oikonomakos NG, Tsitsanou KE, Zographos SE, Skamnaki VT, Goldmann S, Bischoff H. Protein Sci; 1999 Oct 11; 8(10):1930-45. PubMed ID: 10548038 [Abstract] [Full Text] [Related]
4. Binding of oxalyl derivatives of beta-d-glucopyranosylamine to muscle glycogen phosphorylase b. Hadjiloi T, Tiraidis C, Chrysina ED, Leonidas DD, Oikonomakos NG, Tsipos P, Gimisis T. Bioorg Med Chem; 2006 Jun 01; 14(11):3872-82. PubMed ID: 16464598 [Abstract] [Full Text] [Related]
5. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding. Alexacou KM, Hayes JM, Tiraidis C, Zographos SE, Leonidas DD, Chrysina ED, Archontis G, Oikonomakos NG, Paul JV, Varghese B, Loganathan D. Proteins; 2008 May 15; 71(3):1307-23. PubMed ID: 18041758 [Abstract] [Full Text] [Related]
10. 1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies. Tsirkone VG, Tsoukala E, Lamprakis C, Manta S, Hayes JM, Skamnaki VT, Drakou C, Zographos SE, Komiotis D, Leonidas DD. Bioorg Med Chem; 2010 May 15; 18(10):3413-25. PubMed ID: 20430629 [Abstract] [Full Text] [Related]
11. Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate. Leonidas DD, Oikonomakos NG, Papageorgiou AC, Acharya KR, Barford D, Johnson LN. Protein Sci; 1992 Sep 15; 1(9):1112-22. PubMed ID: 1304390 [Abstract] [Full Text] [Related]
14. Crystallographic studies on N-azidoacetyl-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine. Petsalakis EI, Chrysina ED, Tiraidis C, Hadjiloi T, Leonidas DD, Oikonomakos NG, Aich U, Varghese B, Loganathan D. Bioorg Med Chem; 2006 Aug 01; 14(15):5316-24. PubMed ID: 16616506 [Abstract] [Full Text] [Related]