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485 related items for PubMed ID: 16973695

  • 1. Cell physiology of cAMP sensor Epac.
    Holz GG, Kang G, Harbeck M, Roe MW, Chepurny OG.
    J Physiol; 2006 Nov 15; 577(Pt 1):5-15. PubMed ID: 16973695
    [Abstract] [Full Text] [Related]

  • 2. Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.
    Holz GG, Chepurny OG, Schwede F.
    Cell Signal; 2008 Jan 15; 20(1):10-20. PubMed ID: 17716863
    [Abstract] [Full Text] [Related]

  • 3. cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.
    Kang G, Chepurny OG, Malester B, Rindler MJ, Rehmann H, Bos JL, Schwede F, Coetzee WA, Holz GG.
    J Physiol; 2006 Jun 15; 573(Pt 3):595-609. PubMed ID: 16613879
    [Abstract] [Full Text] [Related]

  • 4. Epac: effectors and biological functions.
    Roscioni SS, Elzinga CR, Schmidt M.
    Naunyn Schmiedebergs Arch Pharmacol; 2008 Jun 15; 377(4-6):345-57. PubMed ID: 18176800
    [Abstract] [Full Text] [Related]

  • 5. Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells.
    Kang G, Leech CA, Chepurny OG, Coetzee WA, Holz GG.
    J Physiol; 2008 Mar 01; 586(5):1307-19. PubMed ID: 18202100
    [Abstract] [Full Text] [Related]

  • 6. Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes.
    Pereira L, Rehmann H, Lao DH, Erickson JR, Bossuyt J, Chen J, Bers DM.
    Proc Natl Acad Sci U S A; 2015 Mar 31; 112(13):3991-6. PubMed ID: 25829540
    [Abstract] [Full Text] [Related]

  • 7. cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of Epac.
    Qin Y, Stokman G, Yan K, Ramaiahgari S, Verbeek F, de Graauw M, van de Water B, Price LS.
    Br J Pharmacol; 2012 Feb 31; 165(4b):1137-50. PubMed ID: 21745194
    [Abstract] [Full Text] [Related]

  • 8. PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
    Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG.
    Am J Physiol Endocrinol Metab; 2010 Mar 31; 298(3):E622-33. PubMed ID: 20009023
    [Abstract] [Full Text] [Related]

  • 9. PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells.
    Roscioni SS, Kistemaker LE, Menzen MH, Elzinga CR, Gosens R, Halayko AJ, Meurs H, Schmidt M.
    Respir Res; 2009 Sep 29; 10(1):88. PubMed ID: 19788733
    [Abstract] [Full Text] [Related]

  • 10. Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell.
    Holz GG.
    Diabetes; 2004 Jan 29; 53(1):5-13. PubMed ID: 14693691
    [Abstract] [Full Text] [Related]

  • 11. A novel cyclic AMP-dependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation.
    Shi GX, Rehmann H, Andres DA.
    Mol Cell Biol; 2006 Dec 29; 26(23):9136-47. PubMed ID: 17000774
    [Abstract] [Full Text] [Related]

  • 12. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.
    Rangarajan S, Enserink JM, Kuiperij HB, de Rooij J, Price LS, Schwede F, Bos JL.
    J Cell Biol; 2003 Feb 17; 160(4):487-93. PubMed ID: 12578910
    [Abstract] [Full Text] [Related]

  • 13. Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.
    Kang G, Joseph JW, Chepurny OG, Monaco M, Wheeler MB, Bos JL, Schwede F, Genieser HG, Holz GG.
    J Biol Chem; 2003 Mar 07; 278(10):8279-85. PubMed ID: 12496249
    [Abstract] [Full Text] [Related]

  • 14. Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.
    Chepurny OG, Leech CA, Kelley GG, Dzhura I, Dzhura E, Li X, Rindler MJ, Schwede F, Genieser HG, Holz GG.
    J Biol Chem; 2009 Apr 17; 284(16):10728-36. PubMed ID: 19244230
    [Abstract] [Full Text] [Related]

  • 15. Calcium-induced acrosomal exocytosis requires cAMP acting through a protein kinase A-independent, Epac-mediated pathway.
    Branham MT, Mayorga LS, Tomes CN.
    J Biol Chem; 2006 Mar 31; 281(13):8656-66. PubMed ID: 16407249
    [Abstract] [Full Text] [Related]

  • 16. Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets.
    Herfindal L, Nygaard G, Kopperud R, Krakstad C, Døskeland SO, Selheim F.
    Biochem Biophys Res Commun; 2013 Aug 09; 437(4):603-8. PubMed ID: 23850619
    [Abstract] [Full Text] [Related]

  • 17. Protein kinase A inhibition induces EPAC-dependent acrosomal exocytosis in human sperm.
    Itzhakov D, Nitzan Y, Breitbart H.
    Asian J Androl; 2019 Aug 09; 21(4):337-344. PubMed ID: 30632486
    [Abstract] [Full Text] [Related]

  • 18. ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways.
    Liu H, Enyeart JA, Enyeart JJ.
    J Gen Physiol; 2008 Aug 09; 132(2):279-94. PubMed ID: 18663135
    [Abstract] [Full Text] [Related]

  • 19. Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.
    Dremier S, Milenkovic M, Blancquaert S, Dumont JE, Døskeland SO, Maenhaut C, Roger PP.
    Endocrinology; 2007 Oct 09; 148(10):4612-22. PubMed ID: 17584967
    [Abstract] [Full Text] [Related]

  • 20. Epac-mediated Ca(2+) mobilization and exocytosis in inner medullary collecting duct.
    Yip KP.
    Am J Physiol Renal Physiol; 2006 Oct 09; 291(4):F882-90. PubMed ID: 16684923
    [Abstract] [Full Text] [Related]

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